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Neuroscience
Germany
2026
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Biology and Biochemistry
Germany
2023

D-Index & Metrics

Neuroscience

D-Index
155
Citations
93943
World Ranking
132
National Ranking
4

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Germany Leader Award
  • 2025 - Research.com Neuroscience in Germany Leader Award
  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2022 - Research.com Biology and Biochemistry in Germany Leader Award
  • 2018 - The Brain Prize, Lundbeck Foundation For their groundbreaking research on the genetic and molecular basis of Alzheimer’s disease, with far-reaching implications for the development of new therapeutic interventions as well as for the understanding of other neurodegenerative diseases of the brain'
  • 2015 - Metlife Foundation Award for Medical Research in Alzheimer's Disease
  • 2003 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Agricultural and Nutritional Sciences
  • 2002 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology
  • 2002 - Sedgwick Memorial Medal, American Public Health Association
  • 2000 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Christian Haass is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research primarily spans the fields of Medicine and Neuroscience, with a strong focus on specific subfields including Neurology, Physiology, Immunology, Molecular Biology, and Psychiatry and Mental Health.

The main topics that Haass has contributed to throughout their career include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Neurological Disease Mechanisms and Treatments
  • Inflammation biomarkers and pathways
  • Dementia and Cognitive Impairment Research
  • Parkinson's Disease Mechanisms and Treatments
  • Amyotrophic Lateral Sclerosis Research

Haass has published extensively, with significant contributions in several key scientific journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer s & Dementia
  • Molecular Neurodegeneration
  • Nuklearmedizin - NuclearMedicine
  • EMBO Molecular Medicine

Among their recent papers are:

  • "Microglia states and nomenclature: A field at its crossroads," 2022, Neuron
  • "Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease," 2023, Nature
  • "Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region," 2020, EMBO Molecular Medicine
  • "Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition," 2021, eLife
  • "Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases," 2021, Science Translational Medicine

Collaborative work is a notable feature of their career. Frequent coauthors of Haass include:

  • Matthias Brendel
  • Johannes Levin
  • Kai Schlepckow
  • Leonie Beyer
  • Carla Palleis

Christian Haass has received several awards during their career, such as:

  • The Brain Prize, Lundbeck Foundation (2018), for groundbreaking research on the genetic and molecular basis of Alzheimer's disease with implications for therapeutic development and understanding other neurodegenerative diseases of the brain
  • Metlife Foundation Award for Medical Research in Alzheimer's Disease (2015)
  • German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften (2003), Agricultural and Nutritional Sciences
  • Sedgwick Memorial Medal, American Public Health Association (2002)
  • Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology (2002)
  • Member of Academia Europaea (2000)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide.

    Christian Haass;Dennis J. Selkoe

  • The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

    Susanne Krasemann;Susanne Krasemann;Charlotte Madore;Ron Cialic;Caroline Baufeld

  • Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

    Martin Citron;Tilman Oltersdorf;Christian Haass;Lisa McConlogue

  • Microglia states and nomenclature: A field at its crossroads

    Unknown

  • Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

    Sven Lammich;Elzbieta Kojro;Rolf Postina;Sandra Gilbert

  • Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts

    Robert Ehehalt;Patrick Keller;Christian Haass;Christoph Thiele

  • Trafficking and Proteolytic Processing of APP

    Christian Haass;Christoph Kaether;Gopal Thinakaran;Sangram Sisodia

  • Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease.

    Marc Aurel Busche;Gerhard Eichhoff;Gerhard Eichhoff;Helmuth Adelsberger;Helmuth Adelsberger;Dorothee Abramowski

  • Aβ42‐driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

    Rebecca Radde;Tristan Bolmont;Stephan A Kaeser;Janaky Coomaraswamy

  • Control of peripheral nerve myelination by the beta-secretase BACE1.

    Michael Willem;Alistair N. Garratt;Bozidar Novak;Martin Citron

  • TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis.

    Gernot Kleinberger;Yoshinori Yamanishi;Marc Suárez-Calvet;Eva Czirr

  • Subcellular Localization of Wild-Type and Parkinson's Disease-Associated Mutant α-Synuclein in Human and Transgenic Mouse Brain

    Philipp J. Kahle;Manuela Neumann;Laurence Ozmen;Veronika Müller

  • The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway.

    Christian Haass;Cynthia A. Lemere;Anja Capell;Anja Capell;Martin Citron

  • Take five—BACE and the γ-secretase quartet conduct Alzheimer's amyloid β-peptide generation

    Christian Haass

  • Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

    Nicole Exner;Anne Kathrin Lutz;Christian Haass;Konstanze F Winklhofer

  • Constitutive Phosphorylation of the Parkinson's Disease Associated α-Synuclein *

    Masayasu Okochi;Jochen Walter;Akihiko Koyama;Shigeo Nakajo

  • Presenilin-dependent γ-secretase processing of β-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

    Magdalena Sastre;Harald Steiner;Klaus Fuchs;Anja Capell

  • Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease

    Martin Fuhrmann;Tobias Bittner;Christian K E Jung;Steffen Burgold

  • A γ-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish

    Andrea Geling;Harald Steiner;Michael Willem;Laure Bally‐Cuif

  • Loss-of-Function of Human PINK1 Results in Mitochondrial Pathology and Can Be Rescued by Parkin

    Nicole Exner;Bettina Treske;Dominik Paquet;Kira Holmström

  • The presenilins in Alzheimer's disease--proteolysis holds the key.

    Christian Haass;Bart De Strooper

  • Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins

    Kohji Mori;Thomas Arzberger;Thomas Arzberger;Friedrich A. Grässer;Ilse Gijselinck

  • The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue

    Taisuke Tomita;Kei Maruyama;Takaomi C. Saido;Hideaki Kume

Frequent Co-Authors

Matthias Brendel
Matthias Brendel Ludwig-Maximilians-Universität München
Michael Ewers
Michael Ewers Ludwig-Maximilians-Universität München
Martin Dichgans
Martin Dichgans Ludwig-Maximilians-Universität München
Elisabeth Kremmer
Elisabeth Kremmer Max Planck Society
Robert Perneczky
Robert Perneczky Ludwig-Maximilians-Universität München
Christine Van Broeckhoven
Christine Van Broeckhoven University of Antwerp
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania
Matthias Staufenbiel
Matthias Staufenbiel University of Tübingen
Paul Cumming
Paul Cumming Queensland University of Technology

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