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Angel Cedazo-Minguez

Angel Cedazo-Minguez

D-Index & Metrics

Neuroscience

D-Index
45
Citations
9570
World Ranking
6862
National Ranking
141

Overview

Angel Cedazo-Minguez is affiliated with the Karolinska Institute in Sweden. Their research primarily focuses on the interface of medicine, neuroscience, and molecular biology, addressing complex questions related to cholesterol metabolism, neurodegeneration, and cognitive function.

They have published extensively in several fields of study, including Medicine (37 publications), Neuroscience (21 publications), and Biochemistry, Genetics and Molecular Biology (19 publications). Their subfields of expertise are Molecular Biology (14 publications), Neurology (14 publications), Physiology (10 publications), Surgery (8 publications), and Cellular and Molecular Neuroscience (6 publications).

The main topics covered in their work include:

  • Cholesterol and Lipid Metabolism
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Receptor Mechanisms and Signaling
  • Neuroscience and Neuropharmacology Research
  • Tryptophan and brain disorders
  • S100 Proteins and Annexins

Angel Cedazo-Minguez's recent papers demonstrate a focus on cholesterol's role in brain function and neurodegeneration. Key publications include:

  • "27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial" (2021) published in Alzheimer's Research & Therapy
  • "High levels of 27-hydroxycholesterol results in synaptic plasticity alterations in the hippocampus" (2021) published in Scientific Reports
  • "Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration" (2021) published in Molecular Neurobiology
  • "Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice" (2020) published in Aging
  • "CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice" (2024) published in Science Advances

Their collaborative network includes frequent co-authors such as Silvia Maioli, María Latorre-Leal, Patricia Rodriguez-Rodriguez, Anna Matton, and Francesca Eroli, reflecting ongoing partnerships in multidisciplinary studies.

Angel Cedazo-Minguez has contributed regularly to key publication venues, including bioRxiv (Cold Spring Harbor Laboratory) with 6 publications, Alzheimer's & Dementia (3 publications), Alzheimer's Research & Therapy (2 publications), Aging (2 publications), and Science Advances (1 publication).

Best Publications

  • Defeating Alzheimer's disease and other dementias: a priority for European science and society

    Bengt Winblad;Bengt Winblad;Philippe Amouyel;Sandrine Andrieu;Clive Ballard

  • DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy

    Kelly Jean Thomas;Melissa K. McCoy;Jeff Blackinton;Alexandra Beilina

  • Apolipoprotein E epsilon 4 magnifies lifestyle risks for dementia: a population-based study

    Miia Kivipelto;Miia Kivipelto;Suvi Rovio;Tiia Ngandu;Ingemar Kåreholt;Ingemar Kåreholt

  • Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?

    Torbjörn Persson;Bogdan O. Popescu;Angel Cedazo-Minguez

  • Oxysterols and neurodegenerative diseases

    Ingemar Björkhem;Angel Cedazo-Minguez;Valerio Leoni;Steve Meaney

  • Involvement of glutaredoxin-1 and thioredoxin-1 in beta-amyloid toxicity and Alzheimer's disease.

    S. Akterin;R. F. Cowburn;Antonio Miranda-Vizuete;Antonio Miranda-Vizuete;Alberto Jiménez;Alberto Jiménez

  • Pathways to Alzheimer's disease

    J. Hardy;N. Bogdanovic;B. Winblad;E. Portelius

  • Mitochondrial Alterations in PINK1 Deficient Cells Are Influenced by Calcineurin-Dependent Dephosphorylation of Dynamin-Related Protein 1

    Anna Sandebring;Anna Sandebring;Kelly Jean Thomas;Alexandra Beilina;Marcel van der Brug

  • Successful therapies for Alzheimer’s disease: why so many in animal models and none in humans?

    Rafael Franco;Rafael Franco;Angel Cedazo-Minguez

  • Toward a Predictive Model of Alzheimer’s Disease Progression Using Capillary Electrophoresis–Mass Spectrometry Metabolomics

    Clara Ibáñez;Carolina Simó;Pedro J. Martín-Álvarez;Miia Kivipelto

  • Apolipoprotein E and Alzheimer's disease: molecular mechanisms and therapeutic opportunities

    Angel Cedazo-Mínguez

  • Biomarkers for Alzheimer's disease and other forms of dementia: clinical needs, limitations and future aspects.

    Angel Cedazo-Minguez;Bengt Winblad

  • Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.

    Erika Bereczki;Paul T. Francis;David R. Howlett;Joana B. Pereira

  • Apolipoprotein E: a major piece in the Alzheimer's disease puzzle.

    A. Cedazo-Mínguez;R. F. Cowburn

  • Apolipoprotein E and beta-amyloid (1-42) regulation of glycogen synthase kinase-3beta.

    Cedazo-Mínguez A;Popescu Bo;Blanco-Millán Jm;Akterin S

  • Decreased levels of guanosine 3', 5'-monophosphate (cGMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in Alzheimer's disease.

    Ana Ugarte;Francisco Gil-Bea;Carolina García-Barroso;Ángel Cedazo-Minguez

  • Current and emerging avenues for Alzheimer's disease drug targets.

    R. Loera-Valencia;A. Cedazo-Minguez;P.A. Kenigsberg;G. Page

  • A new metabolomic workflow for early detection of Alzheimer's disease.

    Clara Ibáñez;Carolina Simó;Dinesh K. Barupal;Oliver Fiehn

  • Upregulation of Brain Renin Angiotensin System by 27-Hydroxycholesterol in Alzheimer's Disease

    Laura Mateos;Muhammad Al Mustafa Ismail;Francisco Javier Gil-Bea;Valerio Leoni

  • Tau hyperphosphorylation induces oligomeric insulin accumulation and insulin resistance in neurons

    Patricia Rodriguez-Rodriguez;Anna Sandebring-Matton;Paula Merino-Serrais;Cristina Parrado-Fernandez

  • Activity‐Regulated Cytoskeleton‐Associated Protein in Rodent Brain is Down‐Regulated by High Fat Diet in vivo and by 27‐Hydroxycholesterol in vitro

    Laura Mateos;Susanne Akterin;Francisco-Javier Gil-Bea;Stefan Spulber

Frequent Co-Authors

Miia Kivipelto
Miia Kivipelto University of Eastern Finland
Dag Aarsland
Dag Aarsland King's College London
Kina Höglund
Kina Höglund Sahlgrenska University Hospital
Mark R. Cookson
Mark R. Cookson National Institutes of Health
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Kaj Blennow
Kaj Blennow University of Gothenburg
Roberto Rimondini
Roberto Rimondini University of Bologna
Nenad Bogdanovic
Nenad Bogdanovic Karolinska Institute
Jan Marcusson
Jan Marcusson Linköping University
Paul T. Francis
Paul T. Francis University of Exeter

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