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Neuroscience

D-Index
35
Citations
5643
World Ranking
9161
National Ranking
172

Overview

Kina Höglund is affiliated with Sahlgrenska University Hospital in Sweden. Their research primarily spans the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology. They have contributed significantly to subfields including Physiology, Psychiatry and Mental Health, Neurology, Molecular Biology, and Cellular and Molecular Neuroscience.

Their scholarly work extensively covers topics such as Alzheimer's disease research and treatments, dementia and cognitive impairment research, functional brain connectivity studies, neuroinflammation and neurodegeneration mechanisms, neuroscience and neuropharmacology research, S100 proteins and annexins, as well as acute ischemic stroke management.

Kina Höglund has authored and co-authored several papers published in respected venues. Notable recent publications include:

  • Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts (2020, The Lancet Neurology)
  • An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders (2020, Nature Reviews Neurology)
  • Dissection of synaptic pathways through the CSF biomarkers for predicting Alzheimer disease (2020, Neurology)
  • Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics (2021, Scientific Reports)
  • Plasma phospho-tau217 for Alzheimer's disease diagnosis in primary and secondary care using a fully automated platform (2025, Nature Medicine)

Their frequent co-authors include Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas K. Karikari, and Andréa Lessa Benedet.

Publishing mainly in Alzheimer's & Dementia, Nature Medicine, Journal of Alzheimer's Disease, The Lancet Neurology, and Nature Reviews Neurology, Kina Höglund's research focuses on elucidating underlying biological mechanisms connected to neurodegenerative conditions and improving biomarkers for diagnosis and prognosis.

Best Publications

  • Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts.

    Thomas K. Karikari;Tharick A. Pascoal;Tharick A. Pascoal;Nicholas J. Ashton;Shorena Janelidze

  • Association of Cerebrospinal Fluid Neurofilament Light Protein Levels With Cognition in Patients With Dementia, Motor Neuron Disease, and Movement Disorders

    Bob Olsson;Bob Olsson;Erik Portelius;Erik Portelius;Nicholas C. Cullen;Nicholas C. Cullen;Åsa Sandelius

  • Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology

    Erik Portelius;Erik Portelius;Bob Olsson;Bob Olsson;Kina Höglund;Kina Höglund;Nicholas C. Cullen

  • Synaptic proteins predict cognitive decline in Alzheimer's disease and Lewy body dementia.

    Erika Bereczki;Paul T. Francis;David R. Howlett;Joana B. Pereira

  • Marked increase of β-amyloid (1–42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury

    Annika Olsson;Ludvig Csajbok;Martin Öst;Kina Höglund

  • Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration

    Nicholas J. Ashton;Antoine Leuzy;Yau Mun Lim;Yau Mun Lim;Claire Troakes;Claire Troakes

  • Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients.

    Annika Olsson;Kina Höglund;Magnus Sjögren;Niels Andreasen

  • A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation

    Lorenzo Gaetani;Kina Höglund;Kina Höglund;Lucilla Parnetti;Fani Pujol-Calderon

  • An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders

    Nicholas J. Ashton;Abdul Hye;Abdul Hye;Anto P. Rajkumar;Anto P. Rajkumar;Anto P. Rajkumar;Antoine Leuzy

  • Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.

    Claudia Cicognola;Gunnar Brinkmalm;Jessica Wahlgren;Erik Portelius;Erik Portelius

  • Microglial Markers are Elevated in the Prodromal Phase of Alzheimer's Disease and Vascular Dementia

    Bob Olsson;Joakim Hertze;Ronald Lautner;Henrik Zetterberg

  • Plasma Levels of β-Amyloid(1-40), β-Amyloid(1-42), and Total β-Amyloid Remain Unaffected in Adult Patients With Hypercholesterolemia After Treatment With Statins

    Kina Höglund;Olov Wiklund;Hugo Vanderstichele;Oliver Eikenberg

  • Prevalence of preclinical Alzheimer disease: Comparison of current classification systems.

    Silke Kern;Henrik Zetterberg;Jürgen Kern;Anna Zettergren

  • Neurochemical Aftermath of Repetitive Mild Traumatic Brain Injury.

    Pashtun Shahim;Yelverton Tegner;Bengt Gustafsson;Magnus Gren

  • The Effect of Simvastatin Treatment on the Amyloid Precursor Protein and Brain Cholesterol Metabolism in Patients with Alzheimer’s Disease

    K. Höglund;K.M. Thelen;S. Syversen;M. Sjögren

  • Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology

    Kaj Blennow;Kaj Blennow;Chun Chen;Claudia Cicognola;Kristin R Wildsmith

  • Characterization of Tau in Cerebrospinal Fluid Using Mass Spectrometry

    Erik Portelius;Sara F. Hansson;Ai Jun Tran;Henrik Zetterberg

  • Effect of HMG-CoA reductase inhibitors on beta-amyloid peptide levels: implications for Alzheimer's disease.

    Kina Höglund;Kaj Blennow

  • Dissection of synaptic pathways through the CSF biomarkers for predicting Alzheimer disease.

    Marion Tible;Åsa Sandelius;Åsa Sandelius;Kina Höglund;Kina Höglund;Ann Brinkmalm;Ann Brinkmalm

  • Preclinical amyloid pathology biomarker positivity: effects on tau pathology and neurodegeneration.

    K Höglund;S Kern;S Kern;A Zettergren;A Zettergren;A Börjesson-Hansson;A Börjesson-Hansson

  • The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease

    Hlin Kvartsberg;Tammaryn Lashley;Christina E. Murray;Gunnar Brinkmalm

  • Commentary: Global, regional, and national burden of neurological disorders during 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

    Thomas K. Karikari;Augustina Charway-Felli;Kina Höglund;Kaj Blennow;Kaj Blennow

Frequent Co-Authors

Kaj Blennow
Kaj Blennow University of Gothenburg
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Erik Portelius
Erik Portelius Sahlgrenska University Hospital
Dag Aarsland
Dag Aarsland King's College London
Michael Schöll
Michael Schöll University of Gothenburg
Ulf Andreasson
Ulf Andreasson University of Gothenburg
Angel Cedazo-Minguez
Angel Cedazo-Minguez Karolinska Institute
Hugo Vanderstichele
Hugo Vanderstichele Fujirebio (Belgium)
Vesna Jelic
Vesna Jelic Karolinska University Hospital

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