World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
26205
World Ranking
3303
National Ranking
91

Overview

Keqiang Ye is affiliated with the Shenzhen Institutes of Advanced Technology in China. Their research spans multiple disciplines primarily focused on medicine, neuroscience, and biochemistry, genetics and molecular biology.

The scientist's work covers various subfields including physiology, cellular and molecular neuroscience, neurology, molecular biology, and oncology. Their research topics prominently feature Alzheimer's disease research and treatments, Parkinson's disease mechanisms and treatments, nuclear receptors and signaling, peptidase inhibition and analysis, neuroinflammation and neurodegeneration mechanisms, nerve injury and regeneration, and neurogenesis and neuroplasticity mechanisms.

Frequent collaborators include Xia Liu, Seong Su Kang, Zhentao Zhang, Eun Hee Ahn, and Yiyuan Xia, indicating a network of coauthors contributing significantly to their body of work.

Keqiang Ye has published extensively in several scientific venues. The most frequent publication platforms include:

  • Molecular Psychiatry
  • Progress in Neurobiology
  • Advanced Science
  • Nature Communications
  • eLife

Some of the recent papers authored under their name include:

  • Gut microbiota regulate Alzheimer's disease pathologies and cognitive disorders via PUFA-associated neuroinflammation, 2022, Gut
  • FSH blockade improves cognition in mice with Alzheimer's disease, 2022, Nature
  • Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer's disease mouse model, 2020, Science Advances
  • Development of an α-synuclein positron emission tomography tracer for imaging synucleinopathies, 2023, Cell
  • Gut inflammation triggers C/EBPβ/δ-secretase-dependent gut-to-brain propagation of Aβ and Tau fibrils in Alzheimer's disease, 2021, The EMBO Journal

Best Publications

  • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

    Bin Zhao;Xiaomu Wei;Weiquan Li;Ryan S. Udan;Ryan S. Udan

  • A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

    Sung-Wuk Jang;Xia Liu;Manuel Yepes;Kennie R. Shepherd

  • Dexras1: A G Protein Specifically Coupled to Neuronal Nitric Oxide Synthase via CAPON

    Ming Fang;Samie R. Jaffrey;Akira Sawa;Keqiang Ye

  • Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer’s disease

    Zhentao Zhang;Mingke Song;Xia Liu;Seong Su Kang

  • Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo

    Xianhe Bai;Francesca Cerimele;Masuko Ushio-Fukai;Muhammad Waqas

  • Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth.

    Taro Hitosugi;Lu Zhou;Shannon Elf;Jun Fan

  • Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells

    Keqiang Ye;Yong Ke;Nagalakshmi Keshava;John Shanks

  • PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

    Rong Rong;Jee Yin Ahn;Honglian Huang;Eiichiro Nagata

  • 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling

    Ruiting Lin;Shannon Elf;Changliang Shan;Hee Bum Kang

  • Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease

    Zhentao Zhang;Zhentao Zhang;Mingke Song;Xia Liu;Seong Su Kang

  • Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome

    Christina Gross;Mika Nakamoto;Xiaodi Yao;Chi Bun Chan

  • Effect of 7,8-Dihydroxyflavone, a Small-Molecule TrkB Agonist, on Emotional Learning

    Raul Andero;Scott A. Heldt;Keqiang Ye;Xia Liu

  • SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination

    Hong-Bin Luo;Yi-Yuan Xia;Xi-Ji Shu;Zan-Chao Liu

  • 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease.

    Zhentao Zhang;Xia Liu;Jason P. Schroeder;Chi Bun Chan

  • Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions.

    Hongbo R Luo;Yi Elaine Huang;Jianmeng C Chen;Adolfo Saiardi

  • N-acetylserotonin activates TrkB receptor in a circadian rhythm

    Sung-Wuk Jang;Xia Liu;Sompol Pradoldej;Gianluca Tosini

  • NT3-chitosan elicits robust endogenous neurogenesis to enable functional recovery after spinal cord injury.

    Zhaoyang Yang;Zhaoyang Yang;Aifeng Zhang;Hongmei Duan;Sa Zhang

  • A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect.

    Xia Liu;Chi Bun Chan;Sung Wuk Jang;Sompol Pradoldej

  • Reactive oxygen species-induced actin glutathionylation controls actin dynamics in neutrophils.

    Jiro Sakai;Jingyu Li;Jingyu Li;Kulandayan Kulandayan K Subramanian;Subhanjan Mondal

  • Pike. A nuclear GTPase that enhances PI3kinase activity and is regulated by protein 4.1N

    Keqiang Ye;K.Joseph Hurt;Frederick Y Wu;Ming Fang

Frequent Co-Authors

Jian-Zhi Wang
Jian-Zhi Wang Huazhong University of Science and Technology
Hongbo R. Luo
Hongbo R. Luo Boston Children's Hospital
Kina Höglund
Kina Höglund Sahlgrenska University Hospital
Haian Fu
Haian Fu Emory University
Junmin Peng
Junmin Peng St. Jude Children's Research Hospital
P. Michael Iuvone
P. Michael Iuvone Emory University
Kaj Blennow
Kaj Blennow University of Gothenburg
Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Daniel J. Brat
Daniel J. Brat Northwestern University
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg

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