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D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
14250
World Ranking
9700
National Ranking
741

Overview

Adolfo Saiardi is affiliated with University College London in the United Kingdom. Their research spans fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Agricultural and Biological Sciences. The scientist focuses on several subfields such as Plant Science, Molecular Biology, Nutrition and Dietetics, Genetics, and Surgery.

Their research topics cover a broad range of biological and biochemical processes with particular attention to:

  • Phytase and its Applications
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Iron Metabolism and Disorders
  • Pancreatic function and diabetes
  • Trace Elements in Health
  • Plant nutrient uptake and metabolism
  • Cellular transport and secretion

Saiardi has contributed to publications in several venues, with frequent appearances in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Advances in Biological Regulation
  • Methods in molecular biology
  • Nature Communications
  • Molecular Plant

Recent papers by Saiardi include:

  • Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry, 2020, Nature Communications
  • ITPK1 is an InsP6/ADP phosphotransferase that controls phosphate signaling in Arabidopsis, 2021, Molecular Plant
  • A stable immature lattice packages IP 6 for HIV capsid maturation, 2021, Science Advances
  • Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis, 2020, Journal of Biological Chemistry
  • Polyphosphate degradation by Nudt3-Zn2+ mediates oxidative stress response, 2021, Cell Reports

The scientist frequently collaborates with other researchers, most notably with:

  • Henning J. Jessen
  • Danye Qiu
  • Dorothea Fiedler
  • Gabriel Schaaf
  • Miranda Wilson

Best Publications

  • Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors.

    Ja Hyun Baik;Roberto Picetti;Adolfo Saiardi;Graziella Thiriet

  • Control of eukaryotic phosphate homeostasis by inositol polyphosphate sensor domains.

    Rebekka Wild;Ruta Gerasimaite;Ji-Yul Jung;Vincent Truffault

  • Absence of opiate rewarding effects in mice lacking dopamine D2 receptors

    Rafael Maldonado;Adolfo Saiardi;Olga Valverde;Tarek A. Samad

  • Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases.

    Adolfo Saiardi;Hediye Erdjument-Bromage;Adele M. Snowman;Paul Tempst

  • Abnormal Synaptic Plasticity in the Striatum of Mice Lacking Dopamine D2 Receptors

    Paolo Calabresi;Adolfo Saiardi;Antonio Pisani;Ja Hyun Baik

  • Phosphorylation of Proteins by Inositol Pyrophosphates

    Adolfo Saiardi;Rashna Bhandari;Adam C. Resnick;Adele M. Snowman

  • Role of Dopamine D2-like Receptors in Cocaine Self-Administration: Studies with D2 Receptor Mutant Mice and Novel D2 Receptor Antagonists

    S. Barak Caine;S. Stevens Negus;Nancy K. Mello;Smita Patel

  • Inositol pyrophosphates: between signalling and metabolism

    Miranda S. C. Wilson;Thomas M. Livermore;Adolfo Saiardi

  • Loss of autoreceptor function in dopaminergic neurons from dopamine D2 receptor deficient mice

    Nb Mercuri;A Saiardi;A Bonci;R Picetti

  • Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event.

    Rashna Bhandari;Adolfo Saiardi;Yousef Ahmadibeni;Adele M. Snowman

  • Identification of an evolutionarily conserved family of inorganic polyphosphate endopolyphosphatases.

    Annalisa Lonetti;Zsolt Szijgyarto;Daniel Bosch;Omar Loss

  • Influence of Inositol Pyrophosphates on Cellular Energy Dynamics

    Zsolt Szijgyarto;Assegid Garedew;Cristina Azevedo;Adolfo Saiardi

  • Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic β cells

    Christopher Illies;Jesper Gromada;Roberta Fiume;Barbara Leibiger

  • ANTIPROLIFERATIVE ROLE OF DOPAMINE : LOSS OF D2 RECEPTORS CAUSES HORMONAL DYSFUNCTION AND PITUITARY HYPERPLASIA

    Adolfo Saiardi;Yuri Bozzi;Ja Hyun Baik;Emiliana Borrelli

  • Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions.

    Hongbo R Luo;Yi Elaine Huang;Jianmeng C Chen;Adolfo Saiardi

  • An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons

    Catia Andreassi;Carola Zimmermann;Richard Mitter;Salvatore Fusco

  • The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis.

    Adolfo Saiardi;James J. Caffrey;Solomon H. Snyder;Stephen B. Shears

  • Inositol pyrophosphates regulate endocytic trafficking

    Adolfo Saiardi;Catherine Sciambi;J. Michael McCaffery;Beverly Wendland

  • Inositol pyrophosphates: metabolism and signaling

    M. Bennett;S. M. N. Onnebo;C. Azevedo;A Saiardi

  • Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases

    Adolfo Saiardi;Adam C. Resnick;Adele M. Snowman;Beverly Wendland

Frequent Co-Authors

Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
Tania C. Sorrell
Tania C. Sorrell University of Sydney
Stephen B. Shears
Stephen B. Shears National Institutes of Health
Hongbo R. Luo
Hongbo R. Luo Boston Children's Hospital
Roberto Docampo
Roberto Docampo University of Georgia
Leo C. James
Leo C. James MRC Laboratory of Molecular Biology
Nathalie Boddaert
Nathalie Boddaert Université Paris Cité
Lydie Burglen
Lydie Burglen Hôpital Armand-Trousseau
Giuseppe Passarino
Giuseppe Passarino University of Calabria
Joseph G. Gleeson
Joseph G. Gleeson University of California, San Diego

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