Christine E. Holt

Research.com Recognitions

• 2020 - Member of the National Academy of Sciences
• 2009 - Fellow of the Royal Society, United Kingdom

Overview

Best Publications

• A critical window for cooperation and competition among developing retinotectal synapses

  Li I. Zhang;Huizhong W. Tao;Christine E. Holt;William A. Harris

  1144
  Citations

• Chemotropic Responses of Retinal Growth Cones Mediated by Rapid Local Protein Synthesis and Degradation

  Douglas Simon Campbell;Christine E. Holt

  935
  Citations

• ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function

  Tetsuro Murakami;Seema Qamar;Julie Qiaojin Lin;Gabriele S Kaminski Schierle

  924
  Citations

• FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

  Seema Qamar;Guo Zhen Wang;Suzanne J. Randle;Francesco Simone Ruggeri

  906
  Citations

• Cellular determination in the xenopus retina is independent of lineage and birth date

  Christine E. Holt;Thomas W. Bertsch;Hilary M. Ellis;William A. Harris

  783
  Citations

• cAMP-Dependent Growth Cone Guidance by Netrin-1

  Guo Li Ming;Hong Jun Song;Benedikt Berninger;Christine E. Holt

  748
  Citations

• Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1

  Veit H. Höpker;Derryck Shewan;Marc Tessier-Lavigne;Mu-ming Poo

  711
  Citations

• Mechanosensing is critical for axon growth in the developing brain

  David E Koser;Amelia J Thompson;Sarah K Foster;Asha Dwivedy

  668
  Citations

• Local translation in neurons: visualization and function.

  Christine E Holt;Kelsey C Martin;Erin M Schuman

  583
  Citations

• The Central Dogma Decentralized: New Perspectives on RNA Function and Local Translation in Neurons

  Christine E. Holt;Erin M. Schuman

  579
  Citations

• Asymmetrical β-actin mRNA translation in growth cones mediates attractive turning to netrin-1

  Kin-Mei Leung;Francisca P G van Horck;Andrew C Lin;Rachel Allison

  567
  Citations

• Subcellular mRNA Localization in Animal Cells and Why It Matters

  Christine E. Holt;Simon L. Bullock

  564
  Citations

• Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair

  Hosung Jung;Byung C. Yoon;Christine E. Holt

  556
  Citations

• Axonal Protein Synthesis and Degradation Are Necessary for Efficient Growth Cone Regeneration

  Poonam Verma;Sabrina Chierzi;Amanda M. Codd;Douglas Simon Campbell

  497
  Citations

• Dynamic Axonal Translation in Developing and Mature Visual Circuits

  Toshiaki Shigeoka;Hosung Jung;Jane Jung;Benita Turner-Bridger

  461
  Citations

• Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization.

  Laura F. Gumy;Giles S.H. Yeo;Yi-Chun Loraine Tung;Krishna H. Zivraj

  426
  Citations

• Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons.

  Jean-Michel Cioni;Julie Qiaojin Lin;Anne V. Holtermann;Max Koppers

  425
  Citations

• Apoptotic Pathway and MAPKs Differentially Regulate Chemotropic Responses of Retinal Growth Cones

  Douglas Simon Campbell;Christine E. Holt

  408
  Citations

• Ephrin-B2 and EphB1 Mediate Retinal Axon Divergence at the Optic Chiasm

  Scott E. Williams;Fanny Mann;Lynda Erskine;Lynda Erskine;Takeshi Sakurai

  399
  Citations

• Lipofection of cDNAs in the embryonic vertebrate central nervous system

  Christine E. Holt;Nigel Garlick;Elsa Cornel

  389
  Citations

• Signaling Mechanisms Underlying Slit2-Induced Collapse of Xenopus Retinal Growth Cones

  Michael Piper;Richard Anderson;Asha Dwivedy;Christine Weinl

  381
  Citations