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Alain Prochiantz

Alain Prochiantz

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Biology and Biochemistry
France
2023

D-Index & Metrics

Neuroscience

D-Index
83
Citations
30481
World Ranking
1427
National Ranking
44

Biology and Biochemistry

D-Index
84
Citations
30502
World Ranking
3270
National Ranking
77

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award
  • 2011 - Grand prix de l'Inserm - Institut national de la santé et de la recherche médicale

Overview

Alain Prochiantz is affiliated with the Collège de France in France, with a research focus spanning biochemistry, genetics, molecular biology, and neuroscience. Their work covers several subfields within neuroscience, including molecular biology, cellular and molecular neuroscience, developmental neuroscience, neurology, and endocrine and autonomic systems.

The scientist's research interests center on key topics such as:

  • Neurogenesis and neuroplasticity mechanisms
  • Epigenetics and DNA methylation
  • Retinal development and disorders
  • Neuroscience and neuropharmacology research
  • Nerve injury and regeneration
  • Neuroscience of respiration and sleep
  • Photoreceptor and optogenetics research

Selected recent publications include:

  • Diurnal changes in perineuronal nets and parvalbumin neurons in the rat medial prefrontal cortex, 2021, Brain Structure and Function
  • Non-cell-autonomous OTX2 transcription factor regulates anxiety-related behavior in the mouse, 2021, Molecular Psychiatry
  • Homeoprotein transduction in neurodevelopment and physiopathology, 2020, Science Advances
  • H2O2 and Engrailed 2 paracrine activity synergize to shape the zebrafish optic tectum, 2020, Communications Biology
  • Perturbed DNA methylation by Gadd45b induces chromatin disorganization, DNA strand breaks and dopaminergic neuron death, 2021, iScience

Work is frequently published in venues including bioRxiv (Cold Spring Harbor Laboratory), Molecular Psychiatry, eNeuro, L'annuaire du Collège de France, and Brain Structure and Function.

Prochiantz collaborates regularly with several researchers, with frequent co-authors including Ariel A. Di Nardo, Kenneth L. Moya, David Benacom, C. Vincent, and C. Bernard.

In 2011, Alain Prochiantz was awarded the Grand prix de l'Inserm by the Institut national de la santé et de la recherche médicale.

Best Publications

  • Magnesium gates glutamate-activated channels in mouse central neurones

    L. Nowak;P. Bregestovski;P. Ascher;A. Herbet

  • The third helix of the Antennapedia homeodomain translocates through biological membranes

    D Derossi;A H Joliot;G Chassaing;A Prochiantz

  • Cell Internalization of the Third Helix of the Antennapedia Homeodomain Is Receptor-independent

    Daniele Derossi;Sophie Calvet;Alain Trembleau;Alié Brunissen

  • Trojan peptides: the penetratin system for intracellular delivery

    Daniele Derossi;Gerard Chassaing;Alain Prochiantz

  • Antennapedia homeobox peptide regulates neural morphogenesis

    A Joliot;C Pernelle;H Deagostini-Bazin;A Prochiantz

  • Transduction peptides: from technology to physiology

    Alain Joliot;Alain Prochiantz

  • Experience-dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity

    Sayaka Sugiyama;Ariel A. Di Nardo;Shinichi Aizawa;Isao Matsuo

  • The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment

    Abhishekh Hulegar Ashok;Tiago Andre Reis Marques;Sameer Jauhar;Matthew Nour;Matthew Nour

  • Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone

    Isabelle Caillé;Bernadette Allinquant;Edmond Dupont;Colette Bouillot

  • Otx2 binding to perineuronal nets persistently regulates plasticity in the mature visual cortex.

    Marine Beurdeley;Julien Spatazza;Henry H. C. Lee;Sayaka Sugiyama

  • Messenger proteins: homeoproteins, TAT and others.

    Alain Prochiantz

  • Glial heterogeneity may define the three-dimensional shape of mouse mesencephalic dopaminergic neurones.

    S Denis-Donini;S Denis-Donini;J Glowinski;A Prochiantz

  • Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway

    CM Troy;D Derossi;A Prochiantz;LA Greene

  • Downregulation of Amyloid Precursor Protein Inhibits Neurite Outgrowth In Vitro

    B Allinquant;P Hantraye;P Mailleux;K Moya

  • Brain macrophages synthesize interleukin-1 and interleukin-1 mRNAs in vitro.

    E. Hetier;J. Ayala;P. Denèfle;A. Bousseau

  • The transcription factor Engrailed-2 guides retinal axons

    Isabelle Brunet;Christine Weinl;Michael Piper;Alain Trembleau

  • J1/tenascin in substrate-bound and soluble form displays contrary effects on neurite outgrowth.

    A Lochter;L Vaughan;A Kaplony;A Prochiantz

  • In vitro maturation of mesencephalic dopaminergic neurons from mouse embryos is enhanced in presence of their striatal target cells

    A Prochiantz;U di Porzio;A Kato;B Berger

  • Getting hydrophilic compounds into cells: lessons from homeopeptides

    Alain Prochiantz

  • Effect of striatal cells on in vitro maturation of mesencephalic dopaminergic neurones grown in serum-free conditions

    Umberto di Porzio;Marie-Christine Daguet;Jacques Glowinski;Alain Prochiantz

  • Lipopolysaccharide-stimulated rat brain macrophages release NGF in vitro.

    M. Mallat;R. Houlgatte;P. Brachet;A. Prochiantz

Frequent Co-Authors

Jacques Glowinski
Jacques Glowinski Collège de France
Takao K. Hensch
Takao K. Hensch Harvard University
Gérard Chassaing
Gérard Chassaing Université Paris Cité
Wolfgang Wurst
Wolfgang Wurst German Center for Neurodegenerative Diseases
Marie-Odile Krebs
Marie-Odile Krebs Université Paris Cité
Alain Berthoz
Alain Berthoz Collège de France
Ole Isacson
Ole Isacson Harvard University
Anders Björklund
Anders Björklund Lund University
Antoine Triller
Antoine Triller École Normale Supérieure

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