World's Best Scientists 2026 revealed!
Masahito Ikawa

Masahito Ikawa

Award Badge
Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Molecular Biology

D-Index
101
Citations
36246
World Ranking
511
National Ranking
36

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Masahito Ikawa is affiliated with Osaka University in Japan and has contributed extensively to research in the fields of biochemistry, genetics, and molecular biology, with a particular focus on reproductive medicine. Their work spans various subfields including molecular biology, reproductive medicine, public health, environmental and occupational health, genetics, and immunology.

The scientist's research topics emphasize reproductive biology and fertility, sperm and testicular function, genetic and clinical aspects of sex determination and chromosomal abnormalities, CRISPR and genetic engineering, the reproductive system and pregnancy, epigenetics and DNA methylation, as well as animal genetics and reproduction.

Masahito Ikawa has published papers frequently in several scientific venues, indicating active engagement with the broader research community. These publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Biology of Reproduction
  • Andrology
  • Journal of Reproductive Immunology

Collaborations have been a significant aspect of their work, with frequent co-authors such as:

  • Haruhiko Miyata
  • Martin M. Matzuk
  • Keisuke Shimada
  • Taichi Noda
  • Yonggang Lu

Selected recent papers from Masahito Ikawa's research include:

  • "Structural insights into tetraspanin CD9 function," 2020, Nature Communications
  • "Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility," 2020, The American Journal of Human Genetics
  • "Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm−oocyte fusion in mice," 2020, Proceedings of the National Academy of Sciences
  • "NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility," 2020, Science
  • "Astrocytic cAMP modulates memory via synaptic plasticity," 2021, Proceedings of the National Academy of Sciences

Best Publications

  • Green mice' as a source of ubiquitous green cells

    Masaru Okabe;Masahito Ikawa;Katsuya Kominami;Tomoko Nakanishi

  • Engineered CRISPR-Cas9 nuclease with expanded targeting space

    Hiroshi Nishimasu;Xi Shi;Xi Shi;Soh Ishiguro;Soh Ishiguro;Linyi Gao;Linyi Gao

  • DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

    Satomi Kuramochi-Miyagawa;Toshiaki Watanabe;Kengo Gotoh;Yasushi Totoki

  • The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs

    Naokazu Inoue;Masahito Ikawa;Ayako Isotani;Masaru Okabe

  • Mili, a mammalian member of piwi family gene, is essential for spermatogenesis.

    Satomi Kuramochi-Miyagawa;Tohru Kimura;Takashi W. Ijiri;Taku Isobe

  • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA

    Gustavo Tiscornia;Oded Singer;Masahito Ikawa;Inder M. Verma

  • Innate versus learned odour processing in the mouse olfactory bulb

    Ko Kobayakawa;Reiko Kobayakawa;Hideyuki Matsumoto;Yuichiro Oka

  • Transgenesis by lentiviral vectors: Lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos

    Alexander Pfeifer;Masahito Ikawa;Yelena Dayn;Inder M. Verma

  • PGC7/Stella protects against DNA demethylation in early embryogenesis.

    Toshinobu Nakamura;Yoshikazu Arai;Hiroki Umehara;Masaaki Masuhara

  • Generating green fluorescent mice by germline transmission of green fluorescent ES cells

    Anna Katerina Hadjantonakis;Marina Gertsenstein;Masahito Ikawa;Masaru Okabe

  • Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA.

    Daisuke Mashiko;Yoshitaka Fujihara;Yuhkoh Satouh;Haruhiko Miyata

  • Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model

    Keiichi Kumasawa;Masahito Ikawa;Hiroyasu Kidoya;Hidetoshi Hasuwa

  • Fertilization: a sperm’s journey to and interaction with the oocyte

    Masahito Ikawa;Naokazu Inoue;Adam M. Benham;Masaru Okabe

  • Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality

    Yoshio Hamada;Yuzo Kadokawa;Masaru Okabe;Masahito Ikawa

  • Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.

    Tomohiko Murakami;Atsushi Saito;Shin Ichiro Hino;Shinichi Kondo

  • Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)

    Masato Matsuki;Fumiyoshi Yamashita;Akemi Ishida-Yamamoto;Keiko Yamada

  • The class IV semaphorin CD100 plays nonredundant roles in the immune system : defective B and T cell activation in CD100-deficient mice

    Wei Shi;Atsushi Kumanogoh;Chie Watanabe;Junji Uchida

  • The Putative Chaperone Calmegin is Required for Sperm Fertility

    M. Ikawa;I. Wada;K. Kominami;D. Watanabe

  • Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development

    Masahito Tarutani;Satoshi Itami;Masaru Okabe;Masahito Ikawa

  • Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation.

    Mariko Hara-Chikuma;Eisei Sohara;Tatemitsu Rai;Masahito Ikawa

Frequent Co-Authors

Masaru Okabe
Masaru Okabe Osaka University
Martin M. Matzuk
Martin M. Matzuk Baylor College of Medicine
Yoshitake Nishimune
Yoshitake Nishimune Osaka University
Tadashi Baba
Tadashi Baba University of Tsukuba
Inder M. Verma
Inder M. Verma Salk Institute for Biological Studies
Toru Nakano
Toru Nakano Osaka University
Vinay Tergaonkar
Vinay Tergaonkar Agency for Science, Technology and Research
Taroh Kinoshita
Taroh Kinoshita Osaka University
Atsuo Ogura
Atsuo Ogura University of Tsukuba
Hiroshi Nojima
Hiroshi Nojima Osaka University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Molecular Biology in the USA can open doors to a diverse range of careers, both within and beyond the laboratory environment. Many students wonder about alternative or complementary pathways in the sciences and allied fields, especially those available through flexible online study.

If you are interested in understanding human behavior and the workings of the mind, you may want to explore what can i do with a forensic psychology degree. This field blends biology, psychology, and legal studies for roles in law enforcement, criminal justice, and mental health support.

Those passionate about supporting young people can consider child psychology masters programs online. These programs emphasize developmental biology, mental health, and counseling skills targeted at children and adolescents.

For students looking for broader therapeutic roles, there are affordable options for online masters degrees in counseling. Such programs enable graduates to guide individuals and families through personal and psychological challenges, utilizing valuable insights from biological and behavioral sciences.

Lastly, aspiring clinicians and researchers may be drawn to clinical psychology programs online. These options prepare graduates for direct patient care, diagnostic work, and integrating biological research into mental health practices.

Best Scientists Citing Masahito Ikawa

Trending Scientists

Recently Published Articles