World's Best Scientists 2026 revealed!
Takashi Shinohara

Takashi Shinohara

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
16086
World Ranking
11219
National Ranking
771

Overview

Takashi Shinohara is affiliated with Kyoto University in Japan and has contributed extensively to research in both Medicine and Engineering, with a notable focus on Biomedical Engineering, Public Health, Environmental and Occupational Health, Reproductive Medicine, Molecular Biology, and Genetics. Their scholarly work spans a range of topics including Reproductive Biology and Fertility, Sperm and Testicular Function, Soft Robotics and Applications, Prosthetics and Rehabilitation Robotics, Renal and related cancers, Animal Genetics and Reproduction, and Hydraulic and Pneumatic Systems.

Several recent papers authored or co-authored by Takashi Shinohara demonstrate their involvement in reproductive biology and related fields. These include:

  • Functional primordial germ cell-like cells from pluripotent stem cells in rats, 2022, published in Science
  • Phytochemical Composition and Antioxidant Activity of Passiflora spp. Germplasm Grown in Ecuador, 2022, published in Plants
  • CD2 is a surface marker for mouse and rat spermatogonial stem cells, 2020, published in Journal of Reproduction and Development
  • Autologous transplantation of spermatogonial stem cells restores fertility in congenitally infertile mice, 2020, published in Proceedings of the National Academy of Sciences
  • An interplay of NOX1-derived ROS and oxygen determines the spermatogonial stem cell self-renewal efficiency under hypoxia, 2021, published in Genes & Development

Takashi Shinohara frequently collaborates with several researchers in their field. Key co-authors include Shujiro Dohta, Tetsuya Akagi, Mito Kanatsu-Shinohara, So Shimooka, and Hiroko Morimoto. These collaborations suggest active engagement in interdisciplinary and team-based research environments.

Their research has appeared in multiple peer-reviewed journals and publication venues, with the most frequent ones being:

  • JFPS International Journal of Fluid Power System
  • Stem Cell Reports
  • Journal of Reproduction and Development
  • Journal of Robotics and Mechatronics
  • International Journal of Automotive and Mechanical Engineering

Throughout their academic career, Takashi Shinohara has produced a substantial body of work that integrates science and engineering principles applied to medical and biological challenges. Their interdisciplinary expertise bridges reproductive medicine and engineering fields, contributing to advances in both reproductive biology and technological applications such as robotics and fluid power systems.

Best Publications

  • Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells

    Mito Kanatsu-Shinohara;Narumi Ogonuki;Kimiko Inoue;Hiromi Miki

  • Generation of Pluripotent Stem Cells from Neonatal Mouse Testis

    Mito Kanatsu-Shinohara;Kimiko Inoue;Jiyoung Lee;Momoko Yoshimoto

  • β1- and α6-integrin are surface markers on mouse spermatogonial stem cells

    Takashi Shinohara;Mary R. Avarbock;Ralph L. Brinster

  • Structure and Chromosomal Localization of the Human Stromal Cell-Derived Factor 1 (SDF1) Gene

    Michio Shirozu;Toru Nakano;Johji Inazawa;Kei Tashiro

  • Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells.

    Takashi Shinohara;Kyle E. Orwig;Mary R. Avarbock;Ralph L. Brinster

  • Long-Term Culture of Mouse Male Germline Stem Cells Under Serum-or Feeder-Free Conditions

    Mito Kanatsu-Shinohara;Hiromi Miki;Kimiko Inoue;Narumi Ogonuki

  • Structure and chromosomal localization of the human PD-1 gene (PDCD1)

    Takashi Shinohara;Masafumi Taniwaki;Yasumasa Ishida;Masashi Kawaichi

  • CD9 Is a Surface Marker on Mouse and Rat Male Germline Stem Cells

    Mito Kanatsu-Shinohara;Shinya Toyokuni;Takashi Shinohara

  • Birth of offspring following transplantation of cryopreserved immature testicular pieces and in-vitro microinsemination

    T. Shinohara;K. Inoue;N. Ogonuki;M. Kanatsu-Shinohara

  • Spermatogonial Stem Cell Self-Renewal and Development

    Mito Kanatsu-Shinohara;Takashi Shinohara

  • Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility

    Takashi Shinohara;Kyle E. Orwig;Mary R. Avarbock;Ralph L. Brinster

  • Genetic and epigenetic properties of mouse male germline stem cells during long-term culture

    Mito Kanatsu-Shinohara;Narumi Ogonuki;Tomohiko Iwano;Jiyoung Lee;Jiyoung Lee

  • Akt mediates self-renewal division of mouse spermatogonial stem cells.

    Jiyoung Lee;Mito Kanatsu-Shinohara;Kimiko Inoue;Narumi Ogonuki

  • ROS Are Required for Mouse Spermatogonial Stem Cell Self-Renewal

    Hiroko Morimoto;Kazumi Iwata;Narumi Ogonuki;Kimiko Inoue

  • Functional analysis of spermatogonial stem cells in Steel and cryptorchid infertile mouse models.

    Takashi Shinohara;Mary R. Avarbock;Ralph L. Brinster

  • Homing of Mouse Spermatogonial Stem Cells to Germline Niche Depends on β1-Integrin

    Mito Kanatsu-Shinohara;Masanori Takehashi;Seiji Takashima;Jiyoung Lee

  • FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation

    Kei Ishii;Mito Kanatsu-Shinohara;Shinya Toyokuni;Takashi Shinohara

  • Long-Term Culture of Male Germline Stem Cells From Hamster Testes

    Mito Kanatsu-Shinohara;Tomomi Muneto;Jiyoung Lee;Manami Takenaka

  • Production of knockout mice by random or targeted mutagenesis in spermatogonial stem cells.

    Mito Kanatsu-Shinohara;Masahito Ikawa;Masanori Takehashi;Narumi Ogonuki

  • Restoration of fertility in infertile mice by transplantation of cryopreserved male germline stem cells

    M. Kanatsu‐Shinohara;N. Ogonuki;K. Inoue;A. Ogura

Frequent Co-Authors

Mito Kanatsu-Shinohara
Mito Kanatsu-Shinohara Kyoto University
Atsuo Ogura
Atsuo Ogura University of Tsukuba
Narumi Ogonuki
Narumi Ogonuki National Institutes of Health
Shinya Toyokuni
Shinya Toyokuni Nagoya University
Kimiko Inoue
Kimiko Inoue University of Tsukuba
Tasuku Honjo
Tasuku Honjo Kyoto University
Mitsuo Oshimura
Mitsuo Oshimura Tottori University
Mary R. Avarbock
Mary R. Avarbock University of Pennsylvania
Ralph L. Brinster
Ralph L. Brinster University of Pennsylvania
Kyle E. Orwig
Kyle E. Orwig University of Pittsburgh

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