Bo Chang

Overview

Best Publications

• Retinal degeneration mutants in the mouse.

  B. Chang;N.L. Hawes;R.E. Hurd;M.T. Davisson

  1082
  Citations

• Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice.

  Simon W M John;Richard S. Smith;Olga V. Savinova;Norman L. Hawes

  639
  Citations

• Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice.

  Michael G Anderson;Richard S Smith;Norman L Hawes;Adriana Zabaleta

  522
  Citations

• In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse

  Bo Chang;Hemant Khanna;Norman Hawes;David Jimeno

  425
  Citations

• CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina

  Adrienne K. Mehalow;Shuhei Kameya;Richard S. Smith;Norman L. Hawes

  405
  Citations

• Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice.

  Bo Chang;Richard S Smith;Norman L Hawes;Michael G Anderson

  321
  Citations

• Restoration of cone vision in a mouse model of achromatopsia

  John J Alexander;Yumiko Umino;Drew Everhart;Bo Chang

  297
  Citations

• A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse

  Novrouz B. Akhmedov;Natik I. Piriev;Bo Chang;Ana Lia Rapoport

  295
  Citations

• Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA)

  Ji Jing Pang;Bo Chang;Norman L. Hawes;Ronald E. Hurd

  284
  Citations

• Biology and therapy of inherited retinal degenerative disease: insights from mouse models.

  Shobi Veleri;Csilla H. Lazar;Bo Chang;Paul A. Sieving

  276
  Citations

• Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis.

  Ji-jing Pang;Bo Chang;Ashok Kumar;Steven Nusinowitz

  260
  Citations

• The nob2 mouse, a null mutation in Cacna1f: anatomical and functional abnormalities in the outer retina and their consequences on ganglion cell visual responses.

  Bo Chang;John R. Heckenlively;Philippa R. Bayley;Nicholas C. Brecha

  238
  Citations

• Centrosomal-ciliary gene CEP290/NPHP6 mutations result in blindness with unexpected sparing of photoreceptors and visual brain: implications for therapy of Leber congenital amaurosis.

  Artur V. Cideciyan;Tomas S. Aleman;Samuel G. Jacobson;Hemant Khanna

  210
  Citations

• A homologous genetic basis of the murine cpfl1 mutant and human achromatopsia linked to mutations in the PDE6C gene

  Bo Chang;Tanja Grau;Susann Dangel;Ron Hurd

  205
  Citations

• Mouse model of subretinal neovascularization with choroidal anastomosis.

  John R Heckenlively;Norman L Hawes;Martin Friedlander;Steven Nusinowitz

  196
  Citations

• Mouse fundus photography and angiography: a catalogue of normal and mutant phenotypes.

  Norman L. Hawes;Richard S. Smith;Bo Chang;Muriel Davisson

  195
  Citations

• Long-term retinal function and structure rescue using capsid mutant AAV8 vector in the rd10 mouse, a model of recessive retinitis pigmentosa.

  Ji-jing Pang;Xufeng Dai;Xufeng Dai;Shannon E Boye;Ilaria Barone

  189
  Citations

• Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure

  Bo Chang;Richard S Smith;Maureen Peters;Olga V Savinova

  179
  Citations

• Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans

  Qing Yin Zheng;Denise Yan;Xiao Mei Ouyang;Li Lin Du

  177
  Citations

• Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6

  Shuhei Kameya;Norman L. Hawes;Bo Chang;John R. Heckenlively

  171
  Citations