D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 9,740 178 World Ranking 10554 National Ranking 4585

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • Genetics

Bo Chang spends much of his time researching Genetics, Retinal, Retinal degeneration, Retina and Electroretinography. His work carried out in the field of Genetics brings together such families of science as Achromatopsia, Intraocular pressure, Glaucoma and Retinal Cone Photoreceptor Cells. Genetic enhancement, Genetic model, Ophthalmoscopy and Choroidal neovascularization is closely connected to Anatomy in his research, which is encompassed under the umbrella topic of Retinal.

His Retinal degeneration research incorporates themes from Molecular biology, Retinitis pigmentosa and Frameshift mutation. The Retinitis pigmentosa study combines topics in areas such as Transport protein and Cell biology. In his study, which falls under the umbrella issue of Retina, Color Vision Defects is strongly linked to Pathology.

His most cited work include:

  • Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice. (457 citations)
  • Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice. (364 citations)
  • In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse (315 citations)

What are the main themes of his work throughout his whole career to date?

Bo Chang mainly focuses on Genetics, Retinal degeneration, Retinal, Molecular biology and Retina. Bo Chang has researched Retinal degeneration in several fields, including Retinitis pigmentosa and Pathology. In Retinal, he works on issues like Cell biology, which are connected to Photoreceptor cell.

His study focuses on the intersection of Molecular biology and fields such as Mutant with connections in the field of Exon. His Retina research is multidisciplinary, incorporating perspectives in Genetic enhancement and Anatomy. His work focuses on many connections between Electroretinography and other disciplines, such as Retinal Cone Photoreceptor Cells, that overlap with his field of interest in Achromatopsia.

He most often published in these fields:

  • Genetics (30.69%)
  • Retinal degeneration (29.10%)
  • Retinal (21.69%)

What were the highlights of his more recent work (between 2013-2020)?

  • Molecular biology (20.11%)
  • Retinal pigment epithelium (7.94%)
  • Retinal (21.69%)

In recent papers he was focusing on the following fields of study:

Bo Chang mostly deals with Molecular biology, Retinal pigment epithelium, Retinal, Retina and Cell biology. His Molecular biology research includes elements of Electroretinography, Characterization, Mutant, Mutation and Exudative retinal detachment. His study in Electroretinography is interdisciplinary in nature, drawing from both Erg, Retinal Cone Photoreceptor Cells and Frameshift mutation.

His Retina research focuses on Retinal degeneration in particular. His studies deal with areas such as Allele and Degenerative disease as well as Retinal degeneration. Bo Chang has included themes like Photoreceptor cell, Genetics and LINC complex in his Cell biology study.

Between 2013 and 2020, his most popular works were:

  • Biology and therapy of inherited retinal degenerative disease: insights from mouse models. (141 citations)
  • Adiponectin receptor 1 conserves docosahexaenoic acid and promotes photoreceptor cell survival (66 citations)
  • OTX2 loss causes rod differentiation defect in CRX-associated congenital blindness (44 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • Genetics

Bo Chang mostly deals with Retinal, Retinal pigment epithelium, Retinal degeneration, Anatomy and Retina. The concepts of his Retinal study are interwoven with issues in Cancer research, Angiogenesis, Neovascularization and Cell biology. In his research, Molecular biology and Electroretinography is intimately related to Regulation of gene expression, which falls under the overarching field of Cell biology.

His Retinal degeneration study combines topics from a wide range of disciplines, such as Erg, Genetic enhancement, Neurodegeneration and Outer nuclear layer. His Anatomy research incorporates themes from Gene therapy of the human retina, Retinal Cone Photoreceptor Cells, Edema and Degenerative disease. Retina is a subfield of Neuroscience that Bo Chang tackles.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice.

Simon W M John;Richard S. Smith;Olga V. Savinova;Norman L. Hawes.
Investigative Ophthalmology & Visual Science (1998)

599 Citations

Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice.

Michael G Anderson;Richard S Smith;Norman L Hawes;Adriana Zabaleta.
Nature Genetics (2002)

492 Citations

In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse

Bo Chang;Hemant Khanna;Norman Hawes;David Jimeno.
Human Molecular Genetics (2006)

395 Citations

CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina

Adrienne K. Mehalow;Shuhei Kameya;Richard S. Smith;Norman L. Hawes.
Human Molecular Genetics (2003)

384 Citations

Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice.

Bo Chang;Richard S Smith;Norman L Hawes;Michael G Anderson.
Nature Genetics (1999)

310 Citations

A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse

Novrouz B. Akhmedov;Natik I. Piriev;Bo Chang;Ana Lia Rapoport.
Proceedings of the National Academy of Sciences of the United States of America (2000)

284 Citations

Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA)

Ji Jing Pang;Bo Chang;Norman L. Hawes;Ronald E. Hurd.
Molecular Vision (2005)

275 Citations

Restoration of cone vision in a mouse model of achromatopsia

John J Alexander;Yumiko Umino;Drew Everhart;Bo Chang.
Nature Medicine (2007)

272 Citations

Biology and therapy of inherited retinal degenerative disease: insights from mouse models.

Shobi Veleri;Csilla H. Lazar;Bo Chang;Paul A. Sieving.
Disease Models & Mechanisms (2015)

245 Citations

Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis.

Ji-jing Pang;Bo Chang;Ashok Kumar;Steven Nusinowitz.
Molecular Therapy (2006)

244 Citations

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