D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 70 Citations 15,269 419 World Ranking 1567 National Ranking 725

Research.com Recognitions

Awards & Achievements

2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • DNA

His main research concerns Retinal, Genetics, Retina, Retinitis pigmentosa and Retinal degeneration. His Retinal study integrates concerns from other disciplines, such as Genetic enhancement and Cell biology. His Retina research integrates issues from Immunocytochemistry, Pathology and Anatomy, Optic nerve.

His Retinitis pigmentosa research incorporates elements of Mutation and Rhodopsin. As a part of the same scientific study, he usually deals with the Retinal degeneration, concentrating on Electroretinography and frequently concerns with Point mutation. His Progressive retinal atrophy research includes elements of Locus and Exon.

His most cited work include:

  • Gene therapy restores vision in a canine model of childhood blindness. (1025 citations)
  • Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness (392 citations)
  • Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement (303 citations)

What are the main themes of his work throughout his whole career to date?

Gustavo D. Aguirre mainly focuses on Genetics, Retinal, Retina, Retinal degeneration and Molecular biology. His Genetics and Gene, Progressive retinal atrophy, Locus, Genetic linkage and Candidate gene investigations all form part of his Genetics research activities. His Retinal study combines topics in areas such as Genetic enhancement and Pathology.

His study looks at the relationship between Retina and topics such as Cell biology, which overlap with Mutant. His research in Retinal degeneration intersects with topics in Retinitis pigmentosa and Outer nuclear layer. His Molecular biology study incorporates themes from Complementary DNA, Gene expression and Transducin.

He most often published in these fields:

  • Genetics (30.47%)
  • Retinal (29.61%)
  • Retina (25.75%)

What were the highlights of his more recent work (between 2013-2021)?

  • Retinal (29.61%)
  • Retina (25.75%)
  • Cell biology (15.88%)

In recent papers he was focusing on the following fields of study:

Gustavo D. Aguirre mainly investigates Retinal, Retina, Cell biology, Retinal degeneration and Genetics. The Retinal study combines topics in areas such as Genetic enhancement and Bioinformatics. His Genetic enhancement research incorporates themes from Molecular biology, Cancer research, Recombinant DNA and Virology.

His Retina research is multidisciplinary, incorporating perspectives in In vivo and Pathology. His Cell biology research focuses on Mutant and how it relates to Achromatopsia and Erg. His study on Retinal degeneration also encompasses disciplines like

  • Retinitis pigmentosa, which have a strong connection to Inflammasome,
  • Photoreceptor cell together with Gene therapy of the human retina.

Between 2013 and 2021, his most popular works were:

  • Canine retina has a primate fovea-like bouquet of cone photoreceptors which is affected by inherited macular degenerations. (71 citations)
  • Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells (68 citations)
  • Mutation-independent rhodopsin gene therapy by knockdown and replacement with a single AAV vector. (60 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • DNA

Gustavo D. Aguirre mostly deals with Retinal, Retina, Retinal degeneration, Retinitis pigmentosa and Genetics. His Retinal research is multidisciplinary, incorporating elements of Genetic enhancement and Cell biology. His research integrates issues of Vector and Molecular biology in his study of Genetic enhancement.

His biological study spans a wide range of topics, including Ophthalmology, Anatomy, Bioinformatics and Pathology. Gustavo D. Aguirre interconnects Degeneration, Cancer research, Light damage and Outer nuclear layer in the investigation of issues within Retinal degeneration. His study on Progressive retinal atrophy is often connected to Blindness as part of broader study in Retinitis pigmentosa.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Gene therapy restores vision in a canine model of childhood blindness.

Gregory M. Acland;Gustavo D. Aguirre;Jharna Ray;Qi Zhang.
Nature Genetics (2001)

1453 Citations

Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness

Gregory M. Acland;Gustavo D. Aguirre;Jean Bennett;Tomas S. Aleman.
Molecular Therapy (2005)

542 Citations

Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement

Artur V. Cideciyan;Samuel G. Jacobson;William A. Beltran;Alexander Sumaroka.
Proceedings of the National Academy of Sciences of the United States of America (2013)

456 Citations

Encapsulated cell-based delivery of CNTF reduces photoreceptor degeneration in animal models of retinitis pigmentosa.

Weng Tao;Rong Wen;Moses B Goddard;Sandy D Sherman.
Investigative Ophthalmology & Visual Science (2002)

450 Citations

Unique topographic separation of two spectral classes of cones in the mouse retina

A Szél;P Röhlich;A R Caffé;B Juliusson.
The Journal of Comparative Neurology (1992)

366 Citations

Gene therapy rescues cone function in congenital achromatopsia

András M. Komáromy;John J. Alexander;John J. Alexander;Jessica S. Rowlan;Monique M. Garcia;Monique M. Garcia.
Human Molecular Genetics (2010)

302 Citations

A Linkage Map of the Canine Genome

Cathryn S. Mellersh;Amelia A. Langston;Gregory M. Acland;Melissa A. Fleming.
Genomics (1997)

289 Citations

Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect

Gustavo D Aguirre;Victoria Baldwin;Sue Pearce-Kelling;Kristina Narfström.
Molecular Vision (1998)

285 Citations

Gene therapy rescues photoreceptor blindness in dogs and paves the way for treating human X-linked retinitis pigmentosa

William A. Beltran;Artur V. Cideciyan;Alfred S. Lewin;Simone Iwabe.
Proceedings of the National Academy of Sciences of the United States of America (2012)

285 Citations

A second-generation genetic linkage map of the domestic dog, Canis familiaris.

Mark W. Neff;Karl W. Broman;Cathryn S. Mellersh;Kunal Ray.
Genetics (1999)

282 Citations

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