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D-Index
73
Citations
25043
World Ranking
19562
National Ranking
9738

Overview

Albert M. Maguire is a researcher affiliated with the University of Pennsylvania in the United States. Their main fields of study include Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on ophthalmology and related subfields.

The scientist's research primarily addresses topics within retinal development and disorders, retinal diseases and treatments, as well as ocular diseases and Behçet's syndrome. Their work also touches on cytomegalovirus and herpesvirus research, retinopathy of prematurity studies, retinal and optic conditions, and ophthalmology and visual impairment studies.

Albert M. Maguire has contributed to numerous publications in prominent venues. Frequent journals where their work appears include the American Journal of Ophthalmology Case Reports, Ophthalmology, Molecular Therapy, Translational Vision Science & Technology, and Retinal Cases & Brief Reports.

Recent papers authored or co-authored by Albert M. Maguire include:

  • Durability of Voretigene Neparvovec for Biallelic RPE65-Mediated Inherited Retinal Disease, 2021, Ophthalmology
  • Clinical Perspective: Treating RPE65-Associated Retinal Dystrophy, 2020, Molecular Therapy
  • Gene Editing for CEP290-Associated Retinal Degeneration, 2024, New England Journal of Medicine
  • Adeno-Associated Virus Serotype 2-hCHM Subretinal Delivery to the Macula in Choroideremia, 2022, Ophthalmology
  • Appropriateness of ophthalmic symptoms triage by a popular online artificial intelligence chatbot, 2023, Eye

Throughout their career, Albert M. Maguire has frequently collaborated with several researchers. Notable co-authors include Jean Bennett, Tomás S. Alemán, Leona Serrano, Manzar Ashtari, and Drew Scoles.

Their research spans multiple ophthalmology subfields such as molecular biology, epidemiology, radiology, nuclear medicine and imaging, and cellular and molecular neuroscience. This multidisciplinary approach supports the breadth of their contributions to retinal disease mechanisms and therapeutic strategies.

Best Publications

  • Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

    Albert M. Maguire;Francesca Simonelli;Eric A. Pierce;Edward N. Pugh

  • Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial

    Stephen Russell;Jean Bennett;Jennifer A. Wellman;Daniel C. Chung

  • Gene therapy restores vision in a canine model of childhood blindness.

    Gregory M. Acland;Gustavo D. Aguirre;Jharna Ray;Qi Zhang

  • Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

    Albert M. Maguire;Albert M. Maguire;Katherine A. High;Katherine A. High;Alberto Auricchio;J. Fraser Wright;J. Fraser Wright

  • Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

    Samuel J Reich;Joshua Fosnot;Akiko Kuroki;Waixing Tang

  • Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.

    Francesca Simonelli;Albert M Maguire;Albert M Maguire;Francesco Testa;Eric A Pierce

  • Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness

    Gregory M. Acland;Gustavo D. Aguirre;Jean Bennett;Tomas S. Aleman

  • Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial

    Jean Bennett;Jean Bennett;Jennifer Wellman;Kathleen A Marshall;Sarah McCague

  • AAV2 Gene Therapy Readministration in Three Adults with Congenital Blindness

    Jean Bennett;Jean Bennett;Manzar Ashtari;Jennifer Wellman;Kathleen A. Marshall

  • Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model

    Alberto Auricchio;Gary Kobinger;Vibha Anand;Markus Hildinger

  • Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy

    Jean Bennett;Teruyo Tanabe;Dexue Sun;Dexue Sun;Dexue Sun;Yong Zeng

  • Foveolar choroidal blood flow in age-related macular degeneration.

    J E Grunwald;S M Hariprasad;J DuPont;M G Maguire

  • Three-Year Follow-up after Unilateral Subretinal Delivery of Adeno-Associated Virus in Patients with Leber Congenital Amaurosis Type 2

    Francesco Testa;Albert M. Maguire;Albert M. Maguire;Settimio Rossi;Eric A. Pierce

  • Idiopathic epiretinal membranes. Ultrastructural characteristics and clinicopathologic correlation.

    William E. Smiddy;Albert M. Maguire;W. Richard Green;Ronald G. Michels

  • Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice

    Mariacarmela Allocca;Monica Doria;Marco Petrillo;Pasqualina Colella

  • Single-field fundus photography for diabetic retinopathy screening: a report by the American Academy of Ophthalmology.

    George A Williams;Ingrid U Scott;Julia A Haller;Albert M Maguire

  • Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation-Associated Inherited Retinal Dystrophy: Results of Phase 1 and 3 Trials.

    Albert M. Maguire;Albert M. Maguire;Stephen Russell;Jennifer A. Wellman;Daniel C. Chung

  • Reversal of Blindness in Animal Models of Leber Congenital Amaurosis Using Optimized AAV2-mediated Gene Transfer

    Jeannette Bennicelli;John Fraser Wright;John Fraser Wright;Andras Komaromy;Jonathan B Jacobs

  • Adenovirus vector-mediated in vivo gene transfer into adult murine retina.

    J Bennett;J Wilson;D Sun;B Forbes

  • Long-term protection of retinal structure but not function using RAAV.CNTF in animal models of retinitis pigmentosa.

    Fong-Qi Liang;Tomas S. Aleman;Nadine S. Dejneka;Lorita Dudus

Frequent Co-Authors

Jean Bennett
Jean Bennett University of Pennsylvania
Tomas S. Aleman
Tomas S. Aleman University of Pennsylvania
Daniel C. Chung
Daniel C. Chung Harvard University
Katherine A. High
Katherine A. High Children's Hospital of Philadelphia
James M. Wilson
James M. Wilson University of Pennsylvania
Alberto Auricchio
Alberto Auricchio Telethon Institute Of Genetics And Medicine
Samuel G. Jacobson
Samuel G. Jacobson University of Pennsylvania
Artur V. Cideciyan
Artur V. Cideciyan University of Pennsylvania
Manzar Ashtari
Manzar Ashtari University of Pennsylvania
Eric A. Pierce
Eric A. Pierce Massachusetts Eye and Ear Infirmary

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