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Medicine

D-Index
121
Citations
62889
World Ranking
3568
National Ranking
1963

Overview

David J. McConkey is affiliated with Johns Hopkins University in the United States. Their research is primarily situated within the field of Medicine, with a strong focus on Surgery, Oncology, Molecular Biology, Pulmonary and Respiratory Medicine, and Immunology.

Their work encompasses several key topics, including:

  • Bladder and Urothelial Cancer Treatments
  • Urinary and Genital Oncology Studies
  • Epigenetics and DNA Methylation
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Ferroptosis and cancer prognosis
  • Cancer Research and Treatments

Recent publications associated with David J. McConkey include:

  • "Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomes", 2020, Nature Reviews Urology
  • "Assessment of Luminal and Basal Phenotypes in Bladder Cancer", 2020, Scientific Reports
  • "Identification of Differential Tumor Subtypes of T1 Bladder Cancer", 2020, European Urology
  • "100 years of Bacillus Calmette-Guérin immunotherapy: from cattle to COVID-19", 2021, Nature Reviews Urology
  • "Expression of Nectin-4 in Bladder Urothelial Carcinoma, in Morphologic Variants, and Nonurothelial Histotypes", 2021, Applied Immunohistochemistry & Molecular Morphology

The researcher frequently collaborates with several co-authors, including Woonyoung Choi, Colin P. Dinney, Andrés Matoso, Noah M. Hahn, and Max Kates. These collaborations contribute to the breadth and depth of their publications.

Publications by David J. McConkey appear regularly in several prominent journals, demonstrating consistent engagement with the clinical and research communities. Frequent venues include:

  • Journal of Clinical Oncology
  • The Journal of Urology
  • European Urology
  • Urologic Oncology Seminars and Original Investigations
  • Clinical Cancer Research

The accumulation of publications in these venues indicates an ongoing contribution to research in bladder and urothelial cancers, as well as related oncology fields. Their work addresses both molecular and clinical perspectives, covering mechanisms such as cancer immunotherapy, tumor heterogeneity, and biomarker identification.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang

  • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

    A. Gordon Robertson;Jaegil Kim;Hikmat Al-Ahmadie;Joaquim Bellmunt

  • Identification of Distinct Basal and Luminal Subtypes of Muscle-Invasive Bladder Cancer with Different Sensitivities to Frontline Chemotherapy

    Woonyoung Choi;Sima Porten;Seungchan Kim;Daniel Willis

  • Role of Ca2+ in toxic cell killing

    Sten Orrenius;David J. McConkey;Giorgio Bellomo;Pierluigi Nicotera

  • A Consensus Molecular Classification of Muscle-invasive Bladder Cancer.

    Aurélie Kamoun;Aurélien de Reyniès;Yves Allory;Yves Allory;Gottfrid Sjödahl

  • Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

    Thiruvengadam Arumugam;Vijaya Ramachandran;Keith Francis Fournier;Huamin Wang

  • Autophagy as a target for anticancer therapy

    Filip Janku;David J. McConkey;David S. Hong;Razelle Kurzrock

  • Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy

    Roland Seiler;Roland Seiler;Hussam Al Deen Ashab;Nicholas Erho;Bas W G van Rhijn

  • Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration

    David J. McConkey;Pierluigi Nicotera;Pia Hartzell;Giorgio Bellomo

  • 2,3,7,8-Tetrachlorodibenzo-p-dioxin kills immature thymocytes by Ca2+-mediated endonuclease activation.

    David J. McConkey;Pia Hartzell;Steven K. Duddy;Helen Håkansson

  • Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

    Triona Ni Chonghaile;Kristopher A. Sarosiek;Thanh Trang Vo;Jeremy A. Ryan

  • Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms.

    Christiane J. Bruns;Matthew T. Harbison;Darren W. Davis;Charles A. Portera

  • miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy

    Liana Adam;Meng Zhong;Woonyoung Choi;Wei Qi

  • Antiangiogenic Therapy Targeting the Tyrosine Kinase Receptor for Vascular Endothelial Growth Factor Receptor Inhibits the Growth of Colon Cancer Liver Metastasis and Induces Tumor and Endothelial Cell Apoptosis

    Raymond M. Shaheen;Darren W. Davis;Wenbiao Liu;Brian K. Zebrowski

  • Defects in DNA Repair Genes Predict Response to Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer

    Elizabeth R. Plimack;Roland L. Dunbrack;Timothy A. Brennan;Mark D. Andrake

  • Bax and Bak Promote Apoptosis by Modulating Endoplasmic Reticular and Mitochondrial Ca2+ Stores

    Leta K. Nutt;Abujiang Pataer;Jessica Pahler;Bingliang Fang

  • Calcium-dependent killing of immature thymocytes by stimulation via the CD3/T cell receptor complex.

    D J McConkey;P Hartzell;J F Amador-Pérez;S Orrenius

  • Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells.

    Keyi Zhu;Kenneth Dunner;David J McConkey

  • Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer.

    David J. McConkey;Woonyoung Choi;Lauren Marquis;Frances Martin

Frequent Co-Authors

Colin P. Dinney
Colin P. Dinney The University of Texas MD Anderson Cancer Center
Bogdan Czerniak
Bogdan Czerniak The University of Texas MD Anderson Cancer Center
Sten Orrenius
Sten Orrenius Karolinska Institute
James L. Abbruzzese
James L. Abbruzzese Duke University
Ashish M. Kamat
Ashish M. Kamat The University of Texas MD Anderson Cancer Center
Mikael Jondal
Mikael Jondal Karolinska Institute
Keith A. Baggerly
Keith A. Baggerly The University of Texas MD Anderson Cancer Center
William F. Benedict
William F. Benedict The University of Texas MD Anderson Cancer Center
Seth P. Lerner
Seth P. Lerner Baylor College of Medicine
Pierluigi Nicotera
Pierluigi Nicotera German Center for Neurodegenerative Diseases

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