D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 43 Citations 7,298 94 World Ranking 4617 National Ranking 2146

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Mutation

His primary areas of investigation include Genetics, Retinal, Cis-trans-Isomerases, Ophthalmology and Retinal degeneration. His work deals with themes such as Neovascularization, Retinopathy, Immunology, Vascular endothelial growth factor A and Retina, which intersect with Retinal. Cis-trans-Isomerases is connected with RPE65 and Genetic enhancement in his study.

His research ties Leber's congenital amaurosis and RPE65 together. Eric A. Pierce works on Ophthalmology which deals in particular with Visual acuity. His Retinal degeneration study incorporates themes from Exome sequencing and Cell biology.

His most cited work include:

  • Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis (1728 citations)
  • Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins (1195 citations)
  • Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization (907 citations)

What are the main themes of his work throughout his whole career to date?

Eric A. Pierce mainly focuses on Genetics, Cell biology, Retinitis pigmentosa, Retinal and Retinal degeneration. He works mostly in the field of Cell biology, limiting it down to topics relating to Complement system and, in certain cases, Macular degeneration. His studies in Retinitis pigmentosa integrate themes in fields like Exome sequencing, Missense mutation and Splicing factor, RNA splicing.

His Retinal research is multidisciplinary, relying on both Retina, Computational biology and Genetic enhancement. His research in Retinal degeneration intersects with topics in Dystrophy and NMNAT1. His work on RPE65 and Electroretinography as part of general Ophthalmology study is frequently linked to Cis-trans-Isomerases, bridging the gap between disciplines.

He most often published in these fields:

  • Genetics (39.93%)
  • Cell biology (23.38%)
  • Retinitis pigmentosa (23.38%)

What were the highlights of his more recent work (between 2018-2021)?

  • Genetics (39.93%)
  • Retinitis pigmentosa (23.38%)
  • Gene (16.19%)

In recent papers he was focusing on the following fields of study:

Eric A. Pierce mainly investigates Genetics, Retinitis pigmentosa, Gene, Cell biology and Retinal. CRISPR, Retinal degeneration, Rod-cone dystrophy, Ciliopathy and Mutation are the subjects of his Genetics studies. His Retinitis pigmentosa study integrates concerns from other disciplines, such as Regulator, Rod Photoreceptors and Genetic enhancement.

His Gene study combines topics from a wide range of disciplines, such as Phase i ii and Pathology. Eric A. Pierce works mostly in the field of Cell biology, limiting it down to concerns involving Mutant and, occasionally, Extracellular matrix, Matrix metalloproteinase, Complement system and Complement component 5. His Retinal research integrates issues from Dystrophy, Retina and MEF2C.

Between 2018 and 2021, his most popular works were:

  • The Natural History of Inherited Retinal Dystrophy Due to Biallelic Mutations in the RPE65 Gene. (22 citations)
  • Investigating Cone Photoreceptor Development Using Patient-Derived NRL Null Retinal Organoids (16 citations)
  • Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium (14 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

His primary scientific interests are in Genetics, Retinitis pigmentosa, Gene, Retinal and Retina. The Retinitis pigmentosa study combines topics in areas such as KIFAP3, KIF3A, Kinesin, Genetic enhancement and Ciliopathy. The Genetic enhancement study combines topics in areas such as Retinal degeneration, Computational biology and Induced pluripotent stem cell.

Eric A. Pierce has included themes like Downregulation and upregulation and Cell biology in his Retinal study. His Cell biology research includes themes of Retinal pigment epithelium, PRPF31, Rod Photoreceptors and Haploinsufficiency. The study incorporates disciplines such as Phenotype, Cancer research and Transgene in addition to Retina.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

Albert M. Maguire;Francesca Simonelli;Eric A. Pierce;Edward N. Pugh.
The New England Journal of Medicine (2008)

2236 Citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins

Lloyd Paul Aiello;Eric A. Pierce;Eliot D. Foley;Hitoshi Takagi.
Proceedings of the National Academy of Sciences of the United States of America (1995)

1508 Citations

Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization

Eric Adam Pierce;R. L. Avery;E. D. Foley;Lloyd Paul Aiello.
Proceedings of the National Academy of Sciences of the United States of America (1995)

1177 Citations

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

Albert M. Maguire;Albert M. Maguire;Katherine A. High;Katherine A. High;Alberto Auricchio;J. Fraser Wright;J. Fraser Wright.
The Lancet (2009)

877 Citations

Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.

Francesca Simonelli;Albert M Maguire;Albert M Maguire;Francesco Testa;Eric A Pierce.
Molecular Therapy (2010)

623 Citations

Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity

Eric A. Pierce;Eliot D. Foley;Lois E. H. Smith.
Archives of Ophthalmology (1996)

613 Citations

Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy

Gregory S. Robinson;Eric A. Pierce;Susan L. Rook;Elliot Foley.
Proceedings of the National Academy of Sciences of the United States of America (1996)

468 Citations

Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease.

M. C. Dinauer;E. A. Pierce;G. A. P. Bruns;J. T. Curnutte.
Journal of Clinical Investigation (1990)

440 Citations

AAV2 Gene Therapy Readministration in Three Adults with Congenital Blindness

Jean Bennett;Jean Bennett;Manzar Ashtari;Jennifer Wellman;Kathleen A. Marshall.
Science Translational Medicine (2012)

405 Citations

Specific Double-Stranded RNA Interference in Undifferentiated Mouse Embryonic Stem Cells

Shicheng Yang;Stephen Tutton;Eric Pierce;Kyonggeun Yoon.
Molecular and Cellular Biology (2001)

371 Citations

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