World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
36
Citations
6788
World Ranking
8945
National Ranking
3787

Overview

C. Savio Chan is affiliated with Northwestern University in the United States. Their research primarily focuses on neuroscience and medicine, with a strong emphasis on cellular and molecular neuroscience as well as neurology. Additional subfields include molecular biology, cognitive neuroscience, and genetics.

Their work covers various topics within neurological disorders and treatments, Parkinson's disease mechanisms and treatments, genetic neurodegenerative diseases, and neuroscience and neuropharmacology research. Other areas of research include photoreceptor and optogenetics research, genetics and neurodevelopmental disorders, and neuroscience and neural engineering.

Chan has contributed to multiple papers published in respected venues. Recent publications include:

  • Parvalbumin + and Npas1 + Pallidal Neurons Have Distinct Circuit Topology and Function, 2020, Journal of Neuroscience
  • Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns, 2021, Journal of Neuroscience
  • Cell and circuit complexity of the external globus pallidus, 2023, Nature Neuroscience
  • Molecular, Circuit, and Stress Response Characterization of Ventral Pallidum Npas1-Neurons, 2022, Journal of Neuroscience
  • R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations, 2022, Communications Biology

The scientist frequently publishes in several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroscience
  • Nature Neuroscience
  • Communications Biology
  • Nature Communications

Frequent co-authors include:

  • Arin Pamukcu
  • Harry S. Xenias
  • Suraj Cherian
  • Qiaoling Cui
  • Brianna L. Berceau

Best Publications

  • ‘Rejuvenation’ protects neurons in mouse models of Parkinson’s disease

    C. Savio Chan;Jaime N. Guzman;Ema Ilijic;Jeff N. Mercer

  • Dichotomous Anatomical Properties of Adult Striatal Medium Spiny Neurons

    Tracy S. Gertler;C. Savio Chan;D. James Surmeier

  • Robust Pacemaking in Substantia Nigra Dopaminergic Neurons

    Jaime N. Guzman;Javier Sánchez-Padilla;C. Savio Chan;D. James Surmeier

  • Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches

    Jean Francois Poulin;Giuliana Caronia;Caitlyn Hofer;Qiaoling Cui

  • Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia

    Tim Fieblinger;Steven M. Graves;Luke E. Sebel;Cristina Alcacer

  • Calcium homeostasis, selective vulnerability and Parkinson's disease

    C. Savio Chan;Tracy S. Gertler;D. James Surmeier

  • D2 Dopamine Receptor-Mediated Modulation of Voltage-Dependent Na+ Channels Reduces Autonomous Activity in Striatal Cholinergic Interneurons

    Nicolas Maurice;Jeff Mercer;C. Savio Chan;Salvador Hernandez-Lopez

  • HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons.

    C. Savio Chan;Ryuichi Shigemoto;Jeff N. Mercer;D. James Surmeier

  • Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease.

    Joshua L. Plotkin;Michelle Day;Jayms D. Peterson;Zhong Xie

  • HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease

    C Savio Chan;Kelly E Glajch;Tracy S Gertler;Jaime N Guzman

  • Alternatively Spliced Isoforms of TRIP8b Differentially Control h Channel Trafficking and Function

    Alan S. Lewis;Emily Schwartz;C. Savio Chan;Yoav Noam;Yoav Noam

  • Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus

    Vivian M. Hernández;Daniel J. Hegeman;Qiaoling Cui;Daniel A. Kelver

  • The external globus pallidus: progress and perspectives.

    Daniel J. Hegeman;Ellie S. Hong;Vivian M. Hernández;C. Savio Chan

  • Proliferation of External Globus Pallidus-Subthalamic Nucleus Synapses following Degeneration of Midbrain Dopamine Neurons

    Kai Y. Fan;Jérôme Baufreton;Jérôme Baufreton;D. James Surmeier;C. Savio Chan

  • New roles for the external globus pallidus in basal ganglia circuits and behavior.

    Aryn H. Gittis;Joshua D. Berke;Mark D. Bevan;C. Savio Chan

  • Autonomous pacemakers in the basal ganglia: who needs excitatory synapses anyway?

    D James Surmeier;Jeff N Mercer;C Savio Chan

  • A molecular basis for the increased vulnerability of substantia nigra dopamine neurons in aging and Parkinson's disease

    C. Savio Chan;Tracy S. Gertler;D. James Surmeier

  • Nav1.6 sodium channels are critical to pacemaking and fast spiking in globus pallidus neurons.

    Jeff N. Mercer;C. Savio Chan;Tatiana Tkatch;Joshua Held

  • Corticospinal-specific HCN expression in mouse motor cortex: Ih-dependent synaptic integration as a candidate microcircuit mechanism involved in motor control

    Patrick L. Sheets;Benjamin A. Suter;Taro Kiritani;C. S. Savio Chan

  • Npas1+ Pallidal Neurons Target Striatal Projection Neurons

    Kelly E. Glajch;Daniel A. Kelver;Daniel J. Hegeman;Qiaoling Cui

Frequent Co-Authors

D. James Surmeier
D. James Surmeier Northwestern University
Byung Kook Lim
Byung Kook Lim University of California, San Diego
Charles J. Wilson
Charles J. Wilson The University of Texas at San Antonio
Tatiana Tkatch
Tatiana Tkatch Northwestern University
Wing-Ho Yung
Wing-Ho Yung Chinese University of Hong Kong
Paul Greengard
Paul Greengard Rockefeller University
Vincenzo Crunelli
Vincenzo Crunelli Cardiff University
Dane M. Chetkovich
Dane M. Chetkovich Vanderbilt University Medical Center
Ryuichi Shigemoto
Ryuichi Shigemoto Institute of Science and Technology Austria
Yu Huang
Yu Huang University of California, Los Angeles

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Considering a career in neuroscience can open up exciting opportunities, but it’s important to explore all your options when planning your academic journey. Many students look into which degrees make the most money to ensure they are investing in a profitable future. Fields such as neuroscience often intersect with other high-earning majors in healthcare and technology.

If affordability is a concern, explore fafsa approved online colleges. These institutions can help you access quality education at a lower cost, with the added benefit of federal financial aid.

Short-term credentials are another great way to enhance your skills. Pursuing online certificates can help boost your resume and may provide a pathway into specialized roles related to neuroscience.

For those seeking a flexible study path, you might want to research easy university programs. These online degrees can be more accessible and suitable for balancing work, family, and study, while still preparing you for a range of career opportunities.

Best Scientists Citing C. Savio Chan

Trending Scientists

Recently Published Articles