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Neuroscience

D-Index
36
Citations
8694
World Ranking
8905
National Ranking
3767

Overview

Tatiana Tkatch is affiliated with Northwestern University in the United States. Their research spans several fields within neuroscience and molecular biology, with a focus on cellular and molecular neuroscience. The scientist's work includes studies in neurology, cognitive neuroscience, and pharmacology, reflecting a broad interdisciplinary approach.

The main fields of study for Tatiana Tkatch include:

  • Neuroscience

Key subfields area:

  • Cellular and Molecular Neuroscience
  • Neurology
  • Molecular Biology
  • Cognitive Neuroscience
  • Pharmacology

Primary topics explored in their research are:

  • Neuroscience and Neuropharmacology Research
  • Neural dynamics and brain function
  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Photoreceptor and optogenetics research
  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology

Tatiana Tkatch has contributed to various scientific publications, with recurring appearances in notable journals and preprint servers. Their frequent venues of publication include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • PLoS Biology
  • Scientific Reports
  • Zenodo (CERN European Organization for Nuclear Research)

Recent significant papers authored by or involving Tatiana Tkatch include:

  • Disruption of mitochondrial complex I induces progressive parkinsonism, 2021, Nature
  • Ca 2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons, 2022, Science Advances
  • α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson's disease, 2024, Molecular Neurodegeneration
  • GABAergic regulation of striatal spiny projection neurons depends upon their activity state, 2024, PLoS Biology
  • Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice, 2023, Nature Communications

Collaborations feature prominently in Tkatch's work, with frequent co-authors including:

  • D. James Surmeier
  • David L. Wokosin
  • Enrico Zampese
  • William C. Surmeier
  • Jaime N. Guzmán

Best Publications

  • ‘Rejuvenation’ protects neurons in mouse models of Parkinson’s disease

    C. Savio Chan;Jaime N. Guzman;Ema Ilijic;Jeff N. Mercer

  • Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

    Max B. Kelz;Jingshan Chen;William A. Carlezon;William A. Carlezon;Kim Whisler

  • D2 Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+ Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade

    Salvador Hernández-López;Tatiana Tkatch;Enrique Perez-Garci;Elvira Galarraga

  • Dopaminergic Control of Corticostriatal Long-Term Synaptic Depression in Medium Spiny Neurons Is Mediated by Cholinergic Interneurons

    Zhongfeng Wang;Li Kai;Michelle Day;Jennifer Ronesi

  • Disruption of mitochondrial complex I induces progressive parkinsonism.

    Patricia González-Rodríguez;Enrico Zampese;Kristen A. Stout;Jaime N. Guzman

  • G-Protein-Coupled Receptor Modulation of Striatal CaV1.3 L-Type Ca2+ Channels Is Dependent on a Shank-Binding Domain

    Patricia A. Olson;Tatiana Tkatch;Salvador Hernandez-Lopez;Sasha Ulrich

  • Somatodendritic Depolarization-Activated Potassium Currents in Rat Neostriatal Cholinergic Interneurons Are Predominantly of the A Type and Attributable to Coexpression of Kv4.2 and Kv4.1 Subunits

    W.-J. Song;T. Tkatch;G. Baranauskas;N. Ichinohe

  • D1/D5 Dopamine Receptor Activation Differentially Modulates Rapidly Inactivating and Persistent Sodium Currents in Prefrontal Cortex Pyramidal Neurons

    Nicolas Maurice;Tatiana Tkatch;Miriam Meisler;Leslie K. Sprunger

  • Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons

    Weixing Shen;Xinyong Tian;Michelle Day;Sasha Ulrich

  • RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion

    Jun Ding;Jaime N Guzman;Tatiana Tkatch;Songhai Chen

  • Dendritic Excitability of Mouse Frontal Cortex Pyramidal Neurons Is Shaped by the Interaction among HCN, Kir2, and Kleak Channels

    Michelle Day;David B. Carr;Sasha Ulrich;Ema Ilijic

  • D2 Dopamine Receptor-Mediated Modulation of Voltage-Dependent Na+ Channels Reduces Autonomous Activity in Striatal Cholinergic Interneurons

    Nicolas Maurice;Jeff Mercer;C. Savio Chan;Salvador Hernandez-Lopez

  • Kv4.2 mRNA abundance and A-type K(+) current amplitude are linearly related in basal ganglia and basal forebrain neurons.

    Tatiana Tkatch;Gytis Baranauskas;D. James Surmeier

  • Association of CaV1.3 L-Type Calcium Channels with Shank

    Hua Zhang;Anton Maximov;Yu Fu;Fang Xu

  • HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease

    C Savio Chan;Kelly E Glajch;Tracy S Gertler;Jaime N Guzman

  • Kv3.4 subunits enhance the repolarizing efficiency of Kv3.1 channels in fast-spiking neurons.

    Gytis Baranauskas;Gytis Baranauskas;Tatiana Tkatch;Keiichi Nagata;Jay Z. Yeh

  • Kv1.2-containing K+ channels regulate subthreshold excitability of striatal medium spiny neurons.

    Weixing Shen;Salvador Hernandez-Lopez;Tatiana Tkatch;Joshua E. Held

  • d-Cycloserine reduces neuropathic pain behavior through limbic NMDA-mediated circuitry

    Magali Millecamps;Maria V. Centeno;Hector H. Berra;Charles N. Rudick

  • Delayed rectifier currents in rat globus pallidus neurons are attributable to Kv2.1 and Kv3.1/3.2 K(+) channels.

    Gytis Baranauskas;Tatiana Tkatch;D. James Surmeier

  • Nav1.6 sodium channels are critical to pacemaking and fast spiking in globus pallidus neurons.

    Jeff N. Mercer;C. Savio Chan;Tatiana Tkatch;Joshua Held

Frequent Co-Authors

D. James Surmeier
D. James Surmeier Northwestern University
C. Savio Chan
C. Savio Chan Northwestern University
Charles J. Wilson
Charles J. Wilson The University of Texas at San Antonio
Mark D. Bevan
Mark D. Bevan Northwestern University
Robert C. Foehring
Robert C. Foehring University of Tennessee Health Science Center
Ilya Bezprozvanny
Ilya Bezprozvanny The University of Texas Southwestern Medical Center
Ryuichi Shigemoto
Ryuichi Shigemoto Institute of Science and Technology Austria
Elvira Galarraga
Elvira Galarraga National Autonomous University of Mexico
William E. Armstrong
William E. Armstrong University of Tennessee Health Science Center
William A. Carlezon
William A. Carlezon Harvard University

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