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Pei-Qiang Huang

Pei-Qiang Huang

D-Index & Metrics

Chemistry

D-Index
48
Citations
8729
World Ranking
15199
National Ranking
2356

Overview

Pei-Qiang Huang is affiliated with Xiamen University in China and has contributed extensively to the field of chemistry, with a particular focus on organic chemistry. Their research spans multiple subfields including organic chemistry, materials chemistry, inorganic chemistry, molecular biology, and pharmacology.

The scientist has a significant number of publications, primarily within the domain of chemistry, with a strong emphasis on advanced synthetic organic chemistry and asymmetric catalysis. Key research topics covered in their work include advanced synthetic organic chemistry, asymmetric hydrogenation and catalysis, chemical synthesis and alkaloids, synthetic organic chemistry methods, chemical synthesis and analysis, crystallization and solubility studies, and X-ray diffraction in crystallography.

Frequent publishing venues for Pei-Qiang Huang's research include:

  • The Cambridge Structural Database
  • Organic Chemistry Frontiers
  • The Journal of Organic Chemistry
  • Angewandte Chemie International Edition
  • Angewandte Chemie

Collaborations with other researchers have been a notable aspect of their work. Frequent coauthors include:

  • Jian-Liang Ye
  • Si-Jia Yu
  • Jian-Feng Zheng
  • Dong-Ping Wu
  • Ai-E Wang

Pei-Qiang Huang has contributed to several scientific papers in recent years. Noteworthy publications include:

  • "Enantioselective Reductive Cyanation and Phosphonylation of Secondary Amides by Iridium and Chiral Thiourea Sequential Catalysis," 2021, Angewandte Chemie International Edition
  • "Asymmetric Deoxygenative Alkynylation of Tertiary Amides Enabled by Iridium/Copper Bimetallic Relay Catalysis," 2021, Angewandte Chemie International Edition
  • "Critical Assessment of Metagenome Interpretation - the second round of challenges," 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "Enantioselective total syntheses of (+)-stemofoline and three congeners based on a biogenetic hypothesis," 2020, Nature Communications
  • "Photoredox-Catalyzed Decarboxylative Cross-Coupling of α-Amino Acids with Nitrones," 2021, Organic Letters

Best Publications

  • Direct, one-pot sequential reductive alkylation of lactams/amides with Grignard and organolithium reagents through lactam/amide activation.

    Kai-Jiong Xiao;Jie-Min Luo;Ke-Yin Ye;Yu Wang

  • Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

    Wei-jia Wang;Yuan Wang;Hang-zi Chen;Yong-zhen Xing

  • The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK

    Yan-yan Zhan;Yan Chen;Qian Zhang;Jia-jia Zhuang

  • Direct Transformation of Secondary Amides into Secondary Amines: Triflic Anhydride Activated Reductive Alkylation†

    Kai-Jiong Xiao;Ai-E Wang;Pei-Qiang Huang

  • Asymmetric Synthesis of Hydroxylated Pyrrolidines, Piperidines and Related Bioactive Compounds: From N-Acyliminium Chemistry to N-α-Carbanion Chemistry

    Pei-Qiang Huang

  • Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation

    Li Li;Yuan Liu;Hang-zi Chen;Feng-wei Li

  • A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 In vivo and In vitro

    Jing-jing Liu;Hui-ni Zeng;Lian-ru Zhang;Yan-yan Zhan

  • NSAID Sulindac and Its Analog Bind RXRα and Inhibit RXRα-Dependent AKT Signaling

    Hu Zhou;Wen Liu;Ying Su;Zhen Wei

  • Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols.

    Chen-Xi Ye;Yared Yohannes Melcamu;Heng-Hui Li;Jiang-Tao Cheng

  • Chemoselective reductive alkynylation of tertiary amides by Ir and Cu(I) bis-metal sequential catalysis

    Pei-Qiang Huang;Pei-Qiang Huang;Wei Ou;Feng Han

  • Versatile One-Pot Reductive Alkylation of Lactams/Amides via Amide Activation: Application to the Concise Syntheses of Bioactive Alkaloids (+/-)-Bgugaine, (+/-)-Coniine, (+)-Preussin, and (-)-Cassine

    Kai-Jiong Xiao;Yu Wang;Ke-Yin Ye;Pei-Qiang Huang

  • Asymmetric Synthesis of (+)-L-733, 060 and (+)-CP-99, 994 Based on a New Chiral 3-Piperidinol Synthon†

    Pei-Qiang Huang;Liang-Xian Liu;Bang-Guo Wei;Yuan-Ping Ruan

  • Efficient and chemoselective alkylation of amines/amino acids using alcohols as alkylating reagents under mild conditions

    Chu-Pei Xu;Zhen-Hua Xiao;Bi-Qin Zhuo;Yu-Huang Wang

  • Umpolung of Hemiaminals: Titanocene-Catalyzed Dehydroxylative Radical Coupling Reactions with Activated Alkenes

    Xiao Zheng;Xiao Zheng;Xi-Jie Dai;Hong-Qiu Yuan;Chen-Xi Ye

  • General One-Pot Reductive gem-Bis-Alkylation of Tertiary Lactams/Amides: Rapid Construction of 1-Azaspirocycles and Formal Total Synthesis of (+/-)-Cephalotaxine

    Kai-Jiong Xiao;Jie-Min Luo;Xiao-Er Xia;Yu Wang

  • Metal-Free C-H Alkyliminylation and Acylation of Alkenes with Secondary Amides

    Pei-Qiang Huang;Ying-Hong Huang;Hui Geng;Jian-Liang Ye

  • Asymmetric Vinylogous Mannich Reactions: A Versatile Approach to Functionalized Heterocycles

    Shu-Tang Ruan;Jie-Min Luo;Yu Du;Pei-Qiang Huang

  • A general approach to (5S,6R)-6-alkyl-5-benzyloxy-2-piperidinones: Application to the asymmetric syntheses of neurokinin substance P receptor antagonist (-)-L-733,061 and (-)-deoxocassine

    Liang-Xian Liu;Yuan-Ping Ruan;Zheng-Qing Guo;Pei-Qiang Huang

  • An easy access to protected (4S, 5R)-5-Alkyl-4-hydroxy-2-pyrrolidinones and their use as versatile synthetic intermediates

    Pei Qiang Huang;Shi Li Wang;Jian Liang Ye;Yuan Ping Ruan

  • A general method for the one-pot reductive functionalization of secondary amides.

    Pei-Qiang Huang;Ying-Hong Huang;Kai-Jiong Xiao;Yu Wang

Frequent Co-Authors

Xiao-kun Zhang
Xiao-kun Zhang Xiamen University
YuHuang Wang
YuHuang Wang University of Maryland, College Park
Jiahuai Han
Jiahuai Han Xiamen University
Wai-Yeung Wong
Wai-Yeung Wong Hong Kong Polytechnic University
Sheng-Cai Lin
Sheng-Cai Lin Xiamen University
Huilin Wan
Huilin Wan Xiamen University
Friedrich Beermann
Friedrich Beermann École Polytechnique Fédérale de Lausanne
Gregg Duester
Gregg Duester Sanford Burnham Prebys Medical Discovery Institute
Robert C. Liddington
Robert C. Liddington Discovery Institute
Qinyuan Zhang
Qinyuan Zhang South China University of Technology

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