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Chemistry

D-Index
53
Citations
9640
World Ranking
13113
National Ranking
992

Overview

Atsushi Kato is affiliated with the University of Toyama in Japan and has made notable contributions in the fields of Chemistry, Biochemistry, Genetics and Molecular Biology, and Medicine. Their research primarily focuses on Organic Chemistry, with significant engagement in Molecular Biology, Physiology, Materials Chemistry, and Plant Science.

The primary topics addressed in their work include Carbohydrate Chemistry and Synthesis, Glycosylation and Glycoproteins Research, Lysosomal Storage Disorders Research, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Trypanosoma species research and implications, and Enzyme Production and Characterization.

Among frequent coauthors, Atsushi Kato has collaborated extensively with Yuna Shimadate, George W. J. Fleet, Yi-Xian Li, Chu-Yi Yu, and Yue-Mei Jia.

The main venues for their publications include the European Journal of Medicinal Chemistry, Organic & Biomolecular Chemistry, SSRN Electronic Journal, The Cambridge Structural Database, and Molecules.

Notable recent publications by Atsushi Kato are:

  • 5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease (2022, Journal of Medicinal Chemistry)
  • Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity (2020, Molecules)

Other related papers by colleagues in the same research areas include:

  • Synthesis and glycosidase inhibition of 5-C-alkyl-DNJ and 5-C-alkyl-l-ido-DNJ derivatives (2021, European Journal of Medicinal Chemistry)
  • Synthesis of multimeric pyrrolidine iminosugar inhibitors of human β-glucocerebrosidase and α-galactosidase A: First example of a multivalent enzyme activity enhancer for Fabry disease (2020, European Journal of Medicinal Chemistry)
  • Stereocomplementary synthesis of casuarine and its 6-epi-, 7-epi-, and 6,7-di-epi-stereoisomers (2021, Organic & Biomolecular Chemistry)

Best Publications

  • In vitro inhibition and intracellular enhancement of lysosomal α-galactosidase A activity in Fabry lymphoblasts by 1-deoxygalactonojirimycin and its derivatives

    Naoki Asano;Satoshi Ishii;Haruhisa Kizu;Kyoko Ikeda

  • Iminosugars as therapeutic agents: recent advances and promising trends

    Robert J Nash;Atsushi Kato;Chu-Yi Yu;George Wj Fleet

  • Biological Properties of d- and l-1-Deoxyazasugars

    Atsushi Kato;Noriko Kato;Erika Kano;Isao Adachi

  • Protective Effects of Dietary Chamomile Tea on Diabetic Complications

    Atsushi Kato;Yuka Minoshima;Jo Yamamoto;Isao Adachi

  • Involvement of increased expression of transient receptor potential melastatin 8 in oxaliplatin-induced cold allodynia in mice.

    Punam Gauchan;Tsugunobu Andoh;Atsushi Kato;Yasushi Kuraishi

  • New polyhydroxylated pyrrolizidine alkaloids from Muscari armeniacum: structural determination and biological activity

    Naoki Asano;Hiroyo Kuroi;Kyoko Ikeda;Haruhisa Kizu

  • Antihyperglycemic effects of N-containing sugars from Xanthocercis zambesiaca, Morus bombycis, Aglaonema treubii, and Castanospermum australe in streptozotocin-diabetic mice.

    Hiroshi Nojima;Ikuko Kimura;Fu-jun Chen;Yoshitaka Sugihara

  • Alkaloidal components in the poisonous plant, Ipomoea carnea (Convolvulaceae).

    Mitsue Haraguchi;Silvana Lima Górniak;Kyoko Ikeda;Yasuhiro Minami

  • Polyhydroxylated pyrrolidine and pyrrolizidine alkaloids from Hyacinthoides non-scripta and Scilla campanulata

    Atsushi Kato;Isao Adachi;Miwa Miyauchi;Kyoko Ikeda

  • In vitro inhibition of α*-glucosidases and glycogen phosphorylase by catechin gallates in green tea

    Ogusa Kamiyama;Fujiko Sanae;Kyoko Ikeda;Yasuhiko Higashi

  • Specific alpha-galactosidase inhibitors, N-methylcalystegines--structure/activity relationships of calystegines from Lycium chinense.

    Naoki Asano;Atsushi Kato;Miwa Miyauchi;Haruhisa Kizu

  • α-1-C-Octyl-1-deoxynojirimycin as a pharmacological chaperone for Gaucher disease

    Liang Yu;Kyoko Ikeda;Atsushi Kato;Isao Adachi

  • The l-enantiomers of d-sugar-mimicking iminosugars are noncompetitive inhibitors of d-glycohydrolase?

    Naoki Asano;Kyoko Ikeda;Liang Yu;Atsushi Kato

  • Australine and related alkaloids: easy structural confirmation by 13C NMR spectral data and biological activities

    Atsushi Kato;Erika Kano;Isao Adachi;Russell J. Molyneux

  • Glycosidase-inhibiting pyrrolidine alkaloids from Hyacinthoides non-scripta

    Alison A. Watson;Alison A. Watson;Robert J. Nash;Robert J. Nash;Mark R. Wormald;David J. Harvey

  • Asymmetric synthesis of the four possible fagomine isomers

    Hiroki Takahata;Yasunori Banba;Hidekazu Ouchi;Hideo Nemoto

  • Fagomine isomers and glycosides from Xanthocercis zambesiaca

    Atsushi Kato;Naoki Asano;Haruhisa Kizu;Katsuhiko Matsui

  • The effects of calystegines isolated from edible fruits and vegetables on mammalian liver glycosidases.

    Naoki Asano;Atsushi Kato;Katsuhiko Matsui;Alison A. Watson

  • Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases.

    Yasuhiro Minami;Chinami Kuriyama;Kyoko Ikeda;Atsushi Kato

  • Mechanical Allodynia Induced by Paclitaxel, Oxaliplatin and Vincristine: Different Effectiveness of Gabapentin and Different Expression of Voltage-Dependent Calcium Channel α2δ-1 Subunit

    Punam Gauchan;Tsugunobu Andoh;Kenichiro Ikeda;Masahide Fujita

  • Isolation of Glycosidase-Inhibiting Hyacinthacines and Related Alkaloids from Scilla socialis

    Atsushi Kato;Noriko Kato;Isao Adachi;Jackie Hollinshead

Frequent Co-Authors

George W. J. Fleet
George W. J. Fleet University of Oxford
Robert J. Nash
Robert J. Nash Aberystwyth University
Naoki Asano
Naoki Asano Hokuriku University
Terry D. Butters
Terry D. Butters University of Oxford
Mark R. Wormald
Mark R. Wormald University of Oxford
Haruhisa Kizu
Haruhisa Kizu Hokuriku University
Ken Izumori
Ken Izumori Kagawa University
Frédéric Becq
Frédéric Becq University of Poitiers
Russell J. Molyneux
Russell J. Molyneux University of Hawaii at Hilo
Stephen G. Pyne
Stephen G. Pyne University of Wollongong

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