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Chemistry

D-Index
56
Citations
10353
World Ranking
11715
National Ranking
378

Overview

Andrea Goti is affiliated with the University of Florence in Italy and conducts research primarily in the fields of Chemistry, Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Organic Chemistry, Molecular Biology, Physiology, Materials Chemistry, and Cell Biology.

The main topics of Goti's research include:

  • Carbohydrate Chemistry and Synthesis
  • Lysosomal Storage Disorders Research
  • Glycosylation and Glycoproteins Research
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Synthesis and Catalytic Reactions
  • Chemical Synthesis and Analysis

Goti has frequently published in several scientific venues, reflecting the breadth of their research interests. These venues include:

  • The Cambridge Structural Database
  • Molecules
  • Organic & Biomolecular Chemistry
  • Organic Letters
  • European Journal of Organic Chemistry

Recent notable publications include:

  • Imino- and Azasugar Protonation Inside Human Acid β-Glucosidase, the Enzyme that is Defective in Gaucher Disease (2020, Angewandte Chemie International Edition)
  • Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning (2020, Bioorganic Chemistry)
  • Stimulation of Ca2+-ATPase Transport Activity by a Small-Molecule Drug (2021, ChemMedChem)
  • Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors (2020, ACS Medicinal Chemistry Letters)
  • Piperidine Azasugars Bearing Lipophilic Chains: Stereoselective Synthesis and Biological Activity as Inhibitors of Glucocerebrosidase (GCase) (2021, The Journal of Organic Chemistry)

Throughout their career, Goti has collaborated extensively with coauthors who have contributed frequently to their body of work, including Camilla Matassini, Francesca Cardona, Francesca Clemente, Amelia Morrone, and Cristina Faggi.

Best Publications

  • Heterocycles from alkylidenecyclopropanes.

    Alberto Brandi;Stefano Cicchi;Franca M Cordero;Andrea Goti

  • Metal-catalysed 1,2-diamination reactions.

    Francesca Cardona;Andrea Goti

  • Synthesis of Methylene- and Alkylidenecyclopropane Derivatives.

    Alberto Brandi;Andrea Goti

  • Chloroplast-located flavonoids can scavenge singlet oxygen.

    Giovanni Agati;Paolo Matteini;Paolo Matteini;Andrea Goti;Massimiliano Tattini

  • Progress in the synthesis and transformations of alkylidenecyclopropanes and alkylidenecyclobutanes.

    Alberto Brandi;Stefano Cicchi;Franca M. Cordero;Andrea Goti

  • 1,3-Aminoalcohols by reductive cleavage of isoxazolidines with molybdenum hexacarbonyl

    Stefano Cicchi;Andrea Goti;Alberto Brandi;Antonio Guarna

  • Stereocontrolled Cyclic Nitrone Cycloaddition Strategy for the Synthesis of Pyrrolizidine and Indolizidine Alkaloids

    Alberto Brandi;Francesca Cardona;Stefano Cicchi;Franca M. Cordero

  • Assignment of the Absolute Configuration of Natural Lentiginosine by Synthesis and Enzymic Assays of Optically Pure (+) and (-)-Enantiomers

    Alberto Brandi;Stefano Cicchi;Franca M. Cordero;Roberta Frignoli

  • Total syntheses of hyacinthacine A2 and 7-deoxycasuarine by cycloaddition to a carbohydrate derived nitrone

    Francesca Cardona;Enrico Faggi;Francesca Liguori;Martina Cacciarini

  • Synthesis of nitrones by methyltrioxorhenium catalyzed direct oxidation of secondary amines

    Andrea Goti;Luca Nannelli

  • A Five-Membered Enantiopure Cyclic Nitrone from Malic Acid by Regioselective Oxidation of Cyclic Hydroxylamine. Synthesis of (1S,7S,8aR)-Octahydro-1,7-dihydroxyindolizine

    Stefano Cicchi;Andrea Goti;Alberto Brandi

  • Manganese dioxide oxidation of hydroxylamines to nitrones

    Stefano Cicchi;Marco Marradi;Andrea Goti;Alberto Brandi

  • The Discovery of Novel Metal-Induced Reactions of Nitrones: Not Only Electrophiles and Reagents for [3+2] Cycloadditions

    Francesca Cardona;Andrea Goti

  • Catalytic oxidation of imines based on methyltrioxorhenium/urea hydrogen peroxide: a mild and easy chemo- and regioselective entry to nitrones.

    Gianluca Soldaini;Francesca Cardona;Andrea Goti

  • Total syntheses of casuarine and its 6-O-alpha-glucoside: complementary inhibition towards glycoside hydrolases of the GH31 and GH37 families.

    Francesca Cardona;Camilla Parmeggiani;Enrico Faggi;Claudia Bonaccini

  • Rearrangement of isoxazoline-5-spiro derivatives. 2. Synthesis and rearrangement of tetrahydroisoxazole-5-spirocyclopropanes. Preparation of precursors of quinolizine, isoquinoline, and indole alkaloids

    Alberto Brandi;Sandro Garro;Antonio Guarna;Andrea Goti

  • Nucleophilic Additions to Cyclic Nitrones en Route to Iminocyclitols – Total Syntheses of DMDP, 6-deoxy-DMDP, DAB-1, CYB-3, Nectrisine, and Radicamine B

    Pedro Merino;Ignacio Delso;Ignacio Delso;Tomás Tejero;Francesca Cardona

  • Catalytic oxidation of secondary amines with tetra-n-propylammonium perruthenate

    Andrea Goti;Michela Romani

  • (+)-Lentiginosine, a Potent and Selective Inhibitor of Amyloglucosidase: Synthetic Efforts and Disputes on Its Absolute Configuration

    Francesca Cardona;Andrea Goti;Alberto Brandi

  • Iterative Organometallic Addition to Chiral Hydroxylated Cyclic Nitrones: Highly Stereoselective Syntheses of α,α‘- and α,α-Substituted Hydroxypyrrolidines

    Andrea Goti;Stefano Cicchi;Vanni Mannucci;Francesca Cardona

Frequent Co-Authors

Alberto Brandi
Alberto Brandi University of Florence
Pedro Merino
Pedro Merino University of Zaragoza
Tomas Tejero
Tomas Tejero University of Zaragoza
Armin de Meijere
Armin de Meijere University of Göttingen
Pierre Vogel
Pierre Vogel École Polytechnique Fédérale de Lausanne
Giovanni Agati
Giovanni Agati National Research Council (CNR)
Gideon J. Davies
Gideon J. Davies University of York
Raffaele Saladino
Raffaele Saladino Tuscia University
Claudiu T. Supuran
Claudiu T. Supuran University of Florence
Massimiliano Tattini
Massimiliano Tattini National Research Council (CNR)

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