D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 57 Citations 8,936 268 World Ranking 7860 National Ranking 280

Overview

What is she best known for?

The fields of study she is best known for:

  • Organic chemistry
  • Enzyme
  • Biochemistry

Stereochemistry, Cyclodextrin, Biochemistry, Gene delivery and Enzyme are her primary areas of study. Her study in Stereochemistry focuses on Bicyclic molecule in particular. The Cyclodextrin study combines topics in areas such as Combinatorial chemistry, Cycloaddition, Concanavalin A and Protein–protein interaction.

Carmen Ortiz Mellet usually deals with Combinatorial chemistry and limits it to topics linked to Organic chemistry and Chemical synthesis. Her study in Biochemistry is interdisciplinary in nature, drawing from both Breast cancer cells and Breast cancer. Her Gene delivery research integrates issues from Supramolecular chemistry, Macromolecule, Nanotechnology and DNA.

Her most cited work include:

  • Cyclodextrin-based gene delivery systems (305 citations)
  • Optimizing saccharide-directed molecular delivery to biological receptors: design, synthesis, and biological evaluation of glycodendrimer-cyclodextrin conjugates. (180 citations)
  • Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate–protein interactions (180 citations)

What are the main themes of her work throughout her whole career to date?

Her main research concerns Stereochemistry, Biochemistry, Cyclodextrin, Organic chemistry and Glycoside hydrolase. Her study explores the link between Stereochemistry and topics such as Stereoselectivity that cross with problems in Xylylene. Her Cyclodextrin research includes elements of Combinatorial chemistry, Supramolecular chemistry and Gene delivery.

Her Gene delivery study integrates concerns from other disciplines, such as Macromolecule, Nanotechnology, DNA and Nucleic acid. Her Chaperone research incorporates themes from Glycomimetic and Pharmacological chaperone. Her biological study spans a wide range of topics, including Concanavalin A and Receptor.

She most often published in these fields:

  • Stereochemistry (48.03%)
  • Biochemistry (18.90%)
  • Cyclodextrin (16.93%)

What were the highlights of her more recent work (between 2015-2021)?

  • Biochemistry (18.90%)
  • Stereochemistry (48.03%)
  • Iminosugar (11.81%)

In recent papers she was focusing on the following fields of study:

Carmen Ortiz Mellet mostly deals with Biochemistry, Stereochemistry, Iminosugar, Glycoside hydrolase and Cyclodextrin. The study incorporates disciplines such as Epoxide, Molecular probe and Stereoselectivity in addition to Stereochemistry. Her Iminosugar research is multidisciplinary, incorporating perspectives in Dihydroxylation, Glycoside, Primary, Naringinase and Bicyclic molecule.

Carmen Ortiz Mellet has researched Glycoside hydrolase in several fields, including Lectin, Dendrimer and C glycosides. Her research in Cyclodextrin intersects with topics in Supramolecular chemistry, Nanotechnology, Drug delivery and Gene delivery. Carmen Ortiz Mellet works mostly in the field of Drug delivery, limiting it down to topics relating to Combinatorial chemistry and, in certain cases, Catalysis, as a part of the same area of interest.

Between 2015 and 2021, her most popular works were:

  • Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases (87 citations)
  • Modulation of microglia polarization dynamics during diabetic retinopathy in db/db mice (41 citations)
  • Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition (40 citations)

In her most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • Biochemistry

Her primary areas of investigation include Glycoside hydrolase, Stereochemistry, Biochemistry, Cyclodextrin and Amphiphile. She interconnects Lectin, Iminosugar and C glycosides in the investigation of issues within Glycoside hydrolase. Her Iminosugar study integrates concerns from other disciplines, such as Structure–activity relationship and Moiety.

Her Stereochemistry research integrates issues from Molecular probe and Active site. Biochemistry is closely attributed to Bicyclic molecule in her work. Her studies in Cyclodextrin integrate themes in fields like Nanoparticle, Biophysics, Drug delivery, Drug carrier and Gene delivery.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Cyclodextrin-based gene delivery systems

Carmen Ortiz Mellet;José M. García Fernández;Juan M. Benito.
Chemical Society Reviews (2011)

393 Citations

Optimizing saccharide-directed molecular delivery to biological receptors: design, synthesis, and biological evaluation of glycodendrimer-cyclodextrin conjugates.

Juan M Benito;Marta Gómez-García;Carmen Ortiz Mellet;Isabelle Baussanne.
Journal of the American Chemical Society (2004)

267 Citations

Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate–protein interactions

Álvaro Martínez;Carmen Ortiz Mellet;José Manuel García Fernández.
Chemical Society Reviews (2013)

227 Citations

Glycosidase Inhibition with Fullerene Iminosugar Balls: A Dramatic Multivalent Effect

Philippe Compain;Camille Decroocq;Julien Iehl;Michel Holler.
Angewandte Chemie (2010)

220 Citations

Multivalency in heterogeneous glycoenvironments: hetero-glycoclusters, -glycopolymers and -glycoassemblies

José Luis Jiménez Blanco;Carmen Ortiz Mellet;José Manuel García Fernández.
Chemical Society Reviews (2013)

153 Citations

Probing secondary carbohydrate-protein interactions with highly dense cyclodextrin-centered heteroglycoclusters: the heterocluster effect.

Marta Gómez-García;Juan M Benito;David Rodríguez-Lucena;Jian-Xin Yu.
Journal of the American Chemical Society (2005)

150 Citations

Multivalent iminosugars to modulate affinity and selectivity for glycosidases.

Jennifer Diot;M. Isabel García-Moreno;Sébastien G. Gouin;Carmen Ortiz Mellet.
Organic and Biomolecular Chemistry (2009)

139 Citations

Multivalent Cyclooligosaccharides: Versatile Carbohydrate Clusters with Dual Role as Molecular Receptors and Lectin Ligands

Carmen Ortiz Mellet;Jacques Defaye;José M. García Fernández.
Chemistry: A European Journal (2002)

138 Citations

Pharmacological chaperone therapy for Gaucher disease: a patent review.

Juan M Benito;José M García Fernández;Carmen Ortiz Mellet.
Expert Opinion on Therapeutic Patents (2011)

133 Citations

Multi-Mannosides Based on a Carbohydrate Scaffold: Synthesis, Force Field Development, Molecular Dynamics Studies, and Binding Affinities for Lectin Con A

Sébastien G. Gouin;Enguerran Vanquelef;José Manuel García Fernández;Carmen Ortiz Mellet.
Journal of Organic Chemistry (2007)

130 Citations

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