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Biology and Biochemistry

D-Index
58
Citations
10928
World Ranking
13295
National Ranking
945

Overview

Beate Eckes is affiliated with the University of Cologne in Germany and conducts research primarily in the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their work spans a range of subfields, including Cell Biology, Molecular Biology, Immunology and Allergy, Genetics, and Cancer Research.

The scientist's research topics cover various aspects of cellular and molecular processes. Key areas include:

  • Cell Adhesion Molecules Research
  • Cellular Mechanics and Interactions
  • Connective Tissue Disorders Research
  • Skin and Cellular Biology Research
  • Protease and Inhibitor Mechanisms
  • Wound Healing and Treatments
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Beate Eckes has published extensively in several academic journals. Venues where they have frequently published include:

  • Journal of Investigative Dermatology
  • Nature Communications
  • Annals of the Rheumatic Diseases
  • Wound Repair and Regeneration
  • Molecular Cell

Among recent papers authored or co-authored by Eckes are:

  • TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy (2021, Nature Communications)
  • An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress (2021, Molecular Cell)
  • Role of collagen XII in skin homeostasis and repair (2020, Matrix Biology)
  • Signaling pathways affected by mutations causing osteogenesis imperfecta (2020, Cellular Signalling)
  • Noncanonical WNT5A controls the activation of latent TGF-β to drive fibroblast activation and tissue fibrosis (2024, Journal of Clinical Investigation)

Frequent collaborators include:

  • Mugdha Sawant
  • Thomas Krieg
  • Isabel Zeinert
  • Julian Nüchel
  • Donald Gullberg

Best Publications

  • Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts

    Beate Eckes;Dagmar Dogic;Emma Colucci-Guyon;Ning Wang

  • Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins.

    O Langholz;D Röckel;C Mauch;E Kozlowska

  • Impaired wound healing in embryonic and adult mice lacking vimentin

    B. Eckes;E. Colucci-Guyon;H. Smola;S. Nodder

  • Fibroblasts in mechanically stressed collagen lattices assume a "synthetic" phenotype.

    Daniela Kessler;Silke Dethlefsen;Ingo Haase;Markus Plomann

  • Integrin α2-Deficient Mice Develop Normally, Are Fertile, but Display Partially Defective Platelet Interaction with Collagen

    Olaf Holtkötter;Bernhard Nieswandt;Neil Smyth;Werner Müller

  • Fibroblast-matrix interactions in wound healing and fibrosis.

    Beate Eckes;Paola Zigrino;Daniela Kessler;Olaf Holtkötter

  • Monocyte chemoattractant protein-1 enhances gene expression and synthesis of matrix metalloproteinase-1 in human fibroblasts by an autocrine IL-1 alpha loop.

    Toshiyuki Yamamoto;Beate Eckes;Cornelia Mauch;Karin Hartmann

  • Cell-matrix interactions in dermal repair and scarring

    Beate Eckes;Roswitha Nischt;Thomas Krieg

  • Pathogenesis of fibrosis: type 1 collagen and the skin.

    M Trojanowska;E C LeRoy;B Eckes;T Krieg

  • New developments in fibroblast and myofibroblast biology: Implications for fibrosis and scleroderma

    David J. Abraham;Beate Eckes;Vineeth Rajkumar;Thomas Krieg

  • Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice

    Carsten Deppermann;Deya Cherpokova;Paquita Nurden;Jan-Niklas Schulz

  • Effect of Interleukin-10 on the Gene Expression of Type I Collagen, Fibronectin, and Decorin in Human Skin Fibroblasts: Differential Regulation by Transforming Growth Factor-β and Monocyte Chemoattractant Protein-1

    Toshiyuki Yamamoto;Beate Eckes;Thomas Krieg

  • Expression of integrin β1 by fibroblasts is required for tissue repair in vivo

    Shangxi Liu;Xu Shi-wen;Katrin Blumbach;Mark Eastwood

  • Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo.

    Sabine Grüner;Sabine Grüner;Sabine Grüner;Miroslava Prostredna;Miroslava Prostredna;Miroslava Prostredna;Valerie Schulte;Valerie Schulte;Valerie Schulte;Thomas Krieg;Thomas Krieg;Thomas Krieg

  • Mechanical Tension and Integrin α2β1 Regulate Fibroblast Functions

    Beate Eckes;Manon C. Zweers;Zhi Gang Zhang;Ralf Hallinger

  • The Fibroblast Integrin α11β1 Is Induced in a Mechanosensitive Manner Involving Activin A and Regulates Myofibroblast Differentiation

    Sergio Carracedo;Ning Lu;Svetlana N. Popova;Roland Jonsson

  • Expression of TGF-β1, -β2 and -β3 in localized and systemic scleroderma

    Christiane Querfeld;Beate Eckes;Christina Huerkamp;Thomas Krieg

  • Integrin α2β1 Is Required for Regulation of Murine Wound Angiogenesis but Is Dispensable for Reepithelialization

    Manon C Zweers;Jeffrey M Davidson;Ambra Pozzi;Ralf Hallinger

  • Collagen XII and XIV, New Partners of Cartilage Oligomeric Matrix Protein in the Skin Extracellular Matrix Suprastructure

    Pallavi Agarwal;Daniela Zwolanek;Douglas R. Keene;Jan-Niklas Schulz

  • Integrin α2β1 is the required receptor for endorepellin angiostatic activity

    Benjamin P. Woodall;Alexander Nyström;Rex A. Iozzo;Johannes A. Eble

Frequent Co-Authors

Thomas Krieg
Thomas Krieg University of Cologne
Donald Gullberg
Donald Gullberg University of Bergen
Monique Aumailley
Monique Aumailley University of Cologne
Christopher P. Denton
Christopher P. Denton University College London
Reinhard Fässler
Reinhard Fässler Max Planck Society
Thomas Krieg
Thomas Krieg University of Cambridge
Karin Hartmann
Karin Hartmann University Hospital of Basel
Betty Nusgens
Betty Nusgens University of Liège
Mats Paulsson
Mats Paulsson University of Cologne
Ambra Pozzi
Ambra Pozzi Vanderbilt University Medical Center

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