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Johannes A. Eble

Johannes A. Eble

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
12447
World Ranking
11416
National Ranking
819

Overview

Johannes A. Eble is affiliated with the University of Münster in Germany. Their research spans primarily the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in subfields such as Molecular Biology, Hematology, Oncology, Immunology and Allergy, and Genetics.

The scientist's recent work includes publications on various aspects of tumor microenvironments, cellular interactions, and molecular mechanisms linked to disease progression and treatment. Notable papers include:

  • Matrix Metalloproteinases Shape the Tumor Microenvironment in Cancer Progression (2021, International Journal of Molecular Sciences)
  • A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids (2021, Nature Materials)
  • Hold on or Cut? Integrin- and MMP-Mediated Cell-Matrix Interactions in the Tumor Microenvironment (2020, International Journal of Molecular Sciences)
  • Low-dose Btk inhibitors selectively block platelet activation by CLEC-2 (2020, Haematologica)
  • Thiol switches in membrane proteins - Extracellular redox regulation in cell biology (2020, Biological Chemistry)

Their research covers diverse topics, including:

  • Platelet Disorders and Treatments
  • Cell Adhesion Molecules Research
  • Venomous Animal Envenomation and Studies
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • S100 Proteins and Annexins
  • Biochemical and Structural Characterization
  • Peptidase Inhibition and Analysis

Frequent collaborations have been established with several researchers, highlighting ongoing partnerships in biomedical investigations. Key coauthors include:

  • Stephan Niland
  • Wolfgang M.J. Obermann
  • Simone König
  • Luis A. Morán
  • Ángel Galindo García

Johannes A. Eble has published extensively in various scientific journals, with the most frequent venues being:

  • Toxicon
  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancers
  • Thrombosis and Haemostasis

Best Publications

  • A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2

    Katsue Suzuki-Inoue;Gemma L J Fuller;Angel Garcia;Johannes A Eble

  • The extracellular matrix in tumor progression and metastasis.

    Johannes A Eble;Stephan Niland

  • Urokinase Receptors Promote β1 Integrin Function through Interactions with Integrin α3β1

    Ying Wei;Johannes A. Eble;Zemin Wang;Jordan A. Kreidberg

  • Interaction of type IV collagen with the isolated integrins α1β1 and α2β1

    Andreas Kern;Johannes Eble;Ralph Golbik;Klaus Kuhn

  • The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade.

    Gemma L.J. Fuller;Jennifer A.E. Williams;Michael G. Tomlinson;Johannes A. Eble

  • The alpha 1 beta 1 integrin recognition site of the basement membrane collagen molecule [alpha 1(IV)]2 alpha 2(IV).

    J.A. Eble;R. Golbik;K. Mann;K. Kühn

  • Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange.

    Christian Stock;Birgit Gassner;Christof R. Hauck;Hannelore Arnold

  • Novel aspects of fibrin(ogen) fragments during inflammation.

    Carla Jennewein;Nguyen Tran;Patrick Paulus;Peter Ellinghaus

  • CLEC-2 is an essential platelet activating receptor in hemostasis and thrombosis

    Bernhard Nieswandt;Frauke May

  • The integrin alpha1 A-domain is a ligand binding site for collagens and laminin.

    David A. Calderwood;Danny S. Tuckwell;Johannes Eble;Klaus Kühn

  • The Extracellular Matrix of Blood Vessels

    Johannes A Eble;Stephan Niland

  • CLEC-2 activates Syk through dimerization

    Craig E. Hughes;Alice Y. Pollitt;Jun Mori;Johannes A. Eble

  • A novel flow cytometry–based platelet aggregation assay

    Iris M. De Cuyper;Marjolein Meinders;Edith van de Vijver;Dirk de Korte

  • The structural bases of integrin-ligand interactions

    Klaus Kühn;Johannes Eble

  • α2β1 Integrin Is Not Recognized by Rhodocytin but Is the Specific, High Affinity Target of Rhodocetin, an RGD-independent Disintegrin and Potent Inhibitor of Cell Adhesion to Collagen *

    Johannes A. Eble;Bernd Beermann;Hans-Jürgen Hinz;Alletta Schmidt-Hederich

  • CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils

    Ann M. Kerrigan;Kevin M. Dennehy;Diego Mourao-Sa;Inês Faro-Trindade

  • Cytotoxicity and inhibition of platelet aggregation caused by an l-amino acid oxidase from Bothrops leucurus venom.

    Gustavo B. Naumann;Liliana F. Silva;Luciana Silva;Gilson Faria

  • Integrin α2β1 is the required receptor for endorepellin angiostatic activity

    Benjamin P. Woodall;Alexander Nyström;Rex A. Iozzo;Johannes A. Eble

  • Rhodocytin (Aggretin) Activates Platelets Lacking α2β1 Integrin, Glycoprotein VI, and the Ligand-binding Domain of Glycoprotein Ibα

    Wolfgang Bergmeier;Daniel Bouvard;Johannes A. Eble;Rabée Mokhtari-Nejad

  • Decorin Regulates Endothelial Cell Motility on Collagen I through Activation of Insulin-like Growth Factor I Receptor and Modulation of α2β1 Integrin Activity *

    Lorna Fiedler;Elke Helga Schonherr;Rachel J. Waddington;Stephan Niland

Frequent Co-Authors

Steve P. Watson
Steve P. Watson University of Birmingham
Klaus Kühn
Klaus Kühn Max Planck Society
Philip Lazarovici
Philip Lazarovici Hebrew University of Jerusalem
Christopher A. O’Callaghan
Christopher A. O’Callaghan University of Oxford
Katja Schenke-Layland
Katja Schenke-Layland University of Tübingen
Satya P. Kunapuli
Satya P. Kunapuli Temple University
Thomas Krieg
Thomas Krieg University of Cologne
Juan J. Calvete
Juan J. Calvete Spanish National Research Council
Michael K. Richardson
Michael K. Richardson Leiden University
Jyrki Heino
Jyrki Heino University of Turku

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