His main research concerns Cell biology, Biochemistry, Platelet activation, Sphingosine and Platelet. The Cell biology study combines topics in areas such as Endothelial stem cell and GPVI. Many of his research projects under Biochemistry are closely connected to S1PR1 and Fibrinopeptide with S1PR1 and Fibrinopeptide, tying the diverse disciplines of science together.
His research in Platelet activation intersects with topics in Molecular physics, Radiation, Lymphatic Endothelium and Lymphangiogenesis. His work on Sphingosine-1-phosphate as part of general Sphingosine research is often related to Vascular endothelial growth factor C and Vascular endothelial growth factor B, thus linking different fields of science. His Platelet research includes themes of Diisopropyl fluorophosphate and Serine protease.
His scientific interests lie mostly in Internal medicine, Cardiology, Platelet, Biochemistry and Platelet activation. His study in the field of Heart failure, Myocardial infarction and Acute coronary syndrome is also linked to topics like In patient. His Cardiology research is multidisciplinary, incorporating perspectives in Restenosis and Radiology.
His Platelet research is multidisciplinary, incorporating elements of Whole blood, Biophysics and Pharmacology. His Platelet activation research integrates issues from Receptor and Cell biology. His work carried out in the field of Cell biology brings together such families of science as Sphingosine and Sphingosine-1-phosphate.
Yukio Ozaki mainly investigates Internal medicine, Cardiology, Myocardial infarction, In patient and Cell biology. His biological study deals with issues like Endocrinology, which deal with fields such as Blood sampling. The concepts of his Cardiology study are interwoven with issues in Incidence and Rhythm.
His Cell biology research is multidisciplinary, incorporating elements of Platelet activation, Platelet, Stromal cell and Podoplanin. His Platelet activation research is multidisciplinary, relying on both Cell, Biochemistry, Adenosine and Gene. He combines subjects such as Extracellular, Receptor, Tyrosine phosphorylation, Cyclooxygenase and Aspirin with his study of Platelet.
His primary areas of study are Platelet, Podoplanin, Platelet activation, Cell biology and Receptor. In his study, Knockout mouse, Lung, Alveolar duct and Transforming growth factor is strongly linked to Cancer research, which falls under the umbrella field of Podoplanin. His research integrates issues of Receptor tyrosine kinase, MERTK, GAS6 and Tyrosine phosphorylation in his study of Platelet activation.
His Cell biology study integrates concerns from other disciplines, such as Hemostasis, Convulxin and Pathology. His Receptor research entails a greater understanding of Biochemistry. In his work, Internal medicine is strongly intertwined with Protein kinase B, which is a subfield of C-type lectin.
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Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum
Yutaka Yatomi;Yasuyuki Igarashi;Libo Yang;Nobuo Hisano.
Journal of Biochemistry (1997)
Thrombosis A Major Contributor to Global Disease Burden
G.E. Raskob;P. Angchaisuksiri;A.N. Blanco;H. Buller.
Arteriosclerosis, Thrombosis, and Vascular Biology (2014)
A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2
Katsue Suzuki-Inoue;Gemma L J Fuller;Angel Garcia;Johannes A Eble.
Blood (2006)
Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.
Katsue Suzuki-Inoue;Yukinari Kato;Osamu Inoue;Mika Kato Kaneko.
Journal of Biological Chemistry (2007)
Correlation of tissue and plasma RANTES levels with disease course in patients with breast or cervical cancer.
Yukie Niwa;Hirohiko Akamatsu;Hayato Niwa;Hajime Sumi.
Clinical Cancer Research (2001)
Essential in vivo roles of the c-type lectin receptor CLEC-2: Embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets
Katsue Suzuki-Inoue;Osamu Inoue;Guo Ding;Satoshi Nishimura.
Journal of Biological Chemistry (2010)
Molecular analysis of the pathophysiological binding of the platelet aggregation‐inducing factor podoplanin to the C‐type lectin‐like receptor CLEC‐2
Yukinari Kato;Mika Kato Kaneko;Akiko Kunita;Hiromi Ito.
Cancer Science (2007)
Sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2.
Tsukasa Ohmori;Yutaka Yatomi;Makoto Osada;Fuminori Kazama.
Cardiovascular Research (2003)
Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist
Makoto Osada;Yutaka Yatomi;Tsukasa Ohmori;Hitoshi Ikeda.
Biochemical and Biophysical Research Communications (2002)
Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells.
Yutaka Yatomi;Yutaka Yatomi;Tsukasa Ohmori;Tsukasa Ohmori;Ge Rile;Ge Rile;Fuminori Kazama;Fuminori Kazama.
Blood (2000)
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