Yoh Takuwa

Overview

Best Publications

• Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor.

  Takeshi Sakurai;Masashi Yanagisawa;Yoh Takuwa;Hitoshi Miyazaki

  3073
  Citations

• A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis.

  Takehiko Yokomizo;Takashi Izumi;Kyungho Chang;Yoh Takuwa

  1271
  Citations

• Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils.

  Jingsong Xu;Fei Wang;Alexandra Van Keymeulen;Alexandra Van Keymeulen;Paul Herzmark

  819
  Citations

• Protein kinase C in the regulation of smooth muscle contraction.

  Howard Rasmussen;Yoh Takuwa;Susanna Park

  691
  Citations

• The human preproendothelin-1 gene. Complete nucleotide sequence and regulation of expression.

  A. Inoue;Masashi Yanagisawa;Y. Takuwa;Y. Mitsui

  614
  Citations

• A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts

  N. Takuwa;Y. Takuwa;Masashi Yanagisawa;K. Yamashita

  595
  Citations

• Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle.

  Katsutoshi Goto;Yoshitoshi Kasuya;Norio Matsuki;Yoh Takuwa

  480
  Citations

• Cloning and functional expression of human cDNA for the ETB endothelin receptor

  Aiji Sakamoto;Aiji Sakamoto;Masashi Yanagisawa;Takeshi Sakurai;Yoh Takuwa

  436
  Citations

• EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition.

  Hiroyuki Okamoto;Noriko Takuwa;Koichi Gonda;Hiroshi Okazaki

  407
  Citations

• Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3.

  Hiroyuki Okamoto;Noriko Takuwa;Takehiko Yokomizo;Naotoshi Sugimoto

  391
  Citations

• Inhibitory and Stimulatory Regulation of Rac and Cell Motility by the G12/13-Rho and Gi Pathways Integrated Downstream of a Single G Protein-Coupled Sphingosine-1-Phosphate Receptor Isoform

  Naotoshi Sugimoto;Noriko Takuwa;Hiroyuki Okamoto;Sotaro Sakurada

  380
  Citations

• Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3-E1.

  Yoh Takuwa;Chizuko Ohse;Elizabeth A. Wang;John M. Wozney

  370
  Citations

• Ca2+-Dependent Activation of Rho and Rho Kinase in Membrane Depolarization–Induced and Receptor Stimulation–Induced Vascular Smooth Muscle Contraction

  Sotaro Sakurada;Noriko Takuwa;Naotoshi Sugimoto;Yu Wang

  368
  Citations

• MOLECULAR CLONING AND FUNCTIONAL ANALYSIS OF A NOVEL P2 NUCLEOTIDE RECEPTOR

  Kyungho Chang;Kazuo Hanaoka;Mamoru Kumada;Yoh Takuwa

  325
  Citations

• Statins Activate Peroxisome Proliferator-Activated Receptor γ Through Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase-Dependent Cyclooxygenase-2 Expression in Macrophages

  Miyuki Yano;Takeshi Matsumura;Takafumi Senokuchi;Norio Ishii

  315
  Citations

• The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways

  Koichi Gonda;Hiroyuki Okamoto;Noriko Takuwa;Yutaka Yatomi

  311
  Citations

• Rho kinase inhibitor HA-1077 prevents Rho-mediated myosin phosphatase inhibition in smooth muscle cells.

  Hiromitsu Nagumo;Yasuharu Sasaki;Yoshitaka Ono;Hiroyuki Okamoto

  285
  Citations

• Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1

  Dai Shida;Joji Kitayama;Hironori Yamaguchi;Yurai Okaji

  274
  Citations

• Involvement of rho in GTPγS-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells: inhibition of phosphatase activity

  Masakuni Noda;Chikako Yasuda-Fukazawa;Kohji Moriishi;Tetsuo Kato

  271
  Citations

• EDG3 Is a Functional Receptor Specific for Sphingosine 1-Phosphate and Sphingosylphosphorylcholine with Signaling Characteristics Distinct from EDG1 and AGR16

  Hiroyuki Okamoto;Hiroyuki Okamoto;Noriko Takuwa;Yutaka Yatomi;Koichi Gonda

  265
  Citations