Yutaka Yatomi

Overview

Best Publications

• International clinical harmonization of glycated hemoglobin in Japan: From Japan Diabetes Society to National Glycohemoglobin Standardization Program values.

  Atsunori Kashiwagi;Masato Kasuga;Eiichi Araki;Yoshitomo Oka

  1222
  Citations

• Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum

  Yutaka Yatomi;Yasuyuki Igarashi;Libo Yang;Nobuo Hisano

  665
  Citations

• Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets

  Yutaka Yatomi;Fuqiang Ruan;Sen-itiroh Hakomori;Yasuyuki Igarashi

  639
  Citations

• Involvement of the snake toxin receptor CLEC-2, in podoplanin-mediated platelet activation, by cancer cells.

  Katsue Suzuki-Inoue;Yukinari Kato;Osamu Inoue;Mika Kato Kaneko

  559
  Citations

• Intelligent Image-Activated Cell Sorting

  Nao Nitta;Takeaki Sugimura;Akihiro Isozaki;Hideharu Mikami

  545
  Citations

• Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid

  Masayuki Tanaka;Shinichi Okudaira;Yasuhiro Kishi;Ryunosuke Ohkawa

  540
  Citations

• EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition.

  Hiroyuki Okamoto;Noriko Takuwa;Koichi Gonda;Hiroshi Okazaki

  407
  Citations

• Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ

  Ryosuke Makita;Yasunobu Uchijima;Koichi Nishiyama;Tomokazu Amano

  379
  Citations

• Essential in vivo roles of the c-type lectin receptor CLEC-2: Embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets

  Katsue Suzuki-Inoue;Osamu Inoue;Guo Ding;Satoshi Nishimura

  348
  Citations

• Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood.

  Takamitsu Sano;Daniel L. Baker;Tamas Virag;Atsushi Wada

  340
  Citations

• Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction.

  K E Bornfeldt;L M Graves;E W Raines;Y Igarashi

  324
  Citations

• The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways

  Koichi Gonda;Hiroyuki Okamoto;Noriko Takuwa;Yutaka Yatomi

  311
  Citations

• Induction of Apoptosis by Sphingosine in Human Leukemic HL-60 Cells: A Possible Endogenous Modulator of Apoptotic DNA Fragmentation Occurring during Phorbol Ester-induced Differentiation

  Hideki Ohta;Elizabeth A. Sweeney;Atsushi Masamune;Yutaka Yatomi

  296
  Citations

• Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid.

  Yutaka Yatomi;Soichiro Yamamura;Fuqiang Ruan;Yasuyuki Igarashi

  294
  Citations

• Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C

  Naoko Watanabe;Hitoshi Ikeda;Kazuhiro Nakamura;Ryunosuke Ohkawa

  289
  Citations

• Essential roles of sphingosine 1-phosphate/S1P1 receptor axis in the migration of neural stem cells toward a site of spinal cord injury.

  Atsushi Kimura;Tsukasa Ohmori;Ryunosuke Ohkawa;Seiji Madoiwa

  275
  Citations

• Sphingosine 1-phosphate: synthesis and release.

  Yatomi Y;Ozaki Y;Ohmori T;Igarashi Y

  273
  Citations

• Epigenetic modulation of the renal β-adrenergic-WNK4 pathway in salt-sensitive hypertension.

  ShengYu Mu;Tatsuo Shimosawa;Sayoko Ogura;Hong Wang

  272
  Citations

• Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist

  Makoto Osada;Yutaka Yatomi;Tsukasa Ohmori;Hitoshi Ikeda

  269
  Citations

• Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells.

  Yutaka Yatomi;Tsukasa Ohmori;Tsukasa Ohmori;Ge Rile;Ge Rile;Fuminori Kazama;Fuminori Kazama

  266
  Citations