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Issei Komuro

Issei Komuro

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Medicine
Japan
2023

D-Index & Metrics

Medicine

D-Index
135
Citations
76550
World Ranking
2051
National Ranking
39

Research.com Recognitions

  • 2023 - Research.com Medicine in Japan Leader Award

Overview

Issei Komuro is affiliated with the University of Tokyo in Japan and has contributed extensively to the field of medicine, with a primary focus on cardiology and cardiovascular medicine. Their research spans over 987 publications in medicine, with a concentration on subfields such as cardiology and cardiovascular medicine, molecular biology, surgery, pulmonary and respiratory medicine, and endocrinology, diabetes, and metabolism.

The scientist's work is strongly represented in prominent publication venues. Frequent venues include:

  • International Heart Journal
  • Circulation Journal
  • Scientific Reports
  • European Heart Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Issei Komuro has co-authored numerous papers with several frequent collaborators. These include:

  • Hiroyuki Morita
  • Norifumi Takeda
  • Katsuhito Fujiu
  • Hidehiro Kaneko
  • Hideo Yasunaga

The core topics of their research cover a broad spectrum within cardiovascular studies, including:

  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Heart Failure Treatment and Management
  • Blood Pressure and Hypertension Studies
  • Cardiac Health and Mental Health
  • Atrial Fibrillation Management and Outcomes
  • Diabetes Treatment and Management

Among their recent scientific contributions are several papers published in highly reputed journals. Selected recent works include:

  • "A cross-population atlas of genetic associations for 220 human phenotypes" (2021, Nature Genetics)
  • "Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants" (2022, Nature Genetics)
  • "Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease" (2020, Nature Genetics)
  • "Genome-wide analysis identifies novel susceptibility loci for myocardial infarction" (2020, European Heart Journal)
  • "Heart failure and chronic kidney disease manifestation and mortality risk associations in type 2 diabetes: A large multinational cohort study" (2020, Diabetes Obesity and Metabolism)

Best Publications

  • A cross-population atlas of genetic associations for 220 human phenotypes

    Saori Sakaue;Masahiro Kanai;Yosuke Tanigawa;Juha Karjalainen

  • Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction.

    Tohru Minamino;Hideaki Miyauchi;Toshihiko Yoshida;Yasuo Ishida

  • Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

    Takafumi Oka;Shungo Hikoso;Osamu Yamaguchi;Manabu Taneike;Manabu Taneike

  • The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2014)

    Kazuaki Shimamoto;Katsuyuki Ando;Toshiro Fujita;Naoyuki Hasebe

  • Endothelin stimulates c-fos and c-myc expression and proliferation of vascular smooth muscle cells.

    Issei Komuro;Hiroki Kurihara;Takao Sugiyama;Fumimaro Takaku

  • p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload

    Masanori Sano;Tohru Minamino;Haruhiro Toko;Hideyuki Miyauchi

  • A crucial role for adipose tissue p53 in the regulation of insulin resistance

    Tohru Minamino;Tohru Minamino;Masayuki Orimo;Ippei Shimizu;Takeshige Kunieda

  • Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats

    R Aikawa;I Komuro;T Yamazaki;Y Zou

  • Adult Cardiac Sca-1-positive Cells Differentiate into Beating Cardiomyocytes

    Katsuhisa Matsuura;Toshio Nagai;Nobuhiro Nishigaki;Nobuhiro Nishigaki;Tomomi Oyama

  • Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II

    Yunzeng Zou;Hiroshi Akazawa;Yingjie Qin;Masanori Sano

  • Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation.

    Yukio Hiroi;Sumiyo Kudoh;Koshiro Monzen;Yuichi Ikeda

  • G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes

    Mutsuo Harada;Yingjie Qin;Hiroyuki Takano;Tohru Minamino

  • Csx: a murine homeobox-containing gene specifically expressed in the developing heart.

    Issei Komuro;Seigo Izumo

  • Vascular Cell Senescence: Contribution to Atherosclerosis

    Tohru Minamino;Issei Komuro

  • Stretching cardiac myocytes stimulates protooncogene expression.

    I Komuro;T Kaida;Y Shibazaki;M Kurabayashi

  • Developmental stage-specific biphasic roles of Wnt/β-catenin signaling in cardiomyogenesis and hematopoiesis

    Atsuhiko T. Naito;Ichiro Shiojima;Hiroshi Akazawa;Kyoko Hidaka

  • Inhibition of autophagy in the heart induces age-related cardiomyopathy.

    Manabu Taneike;Osamu Yamaguchi;Atsuko Nakai;Shungo Hikoso

  • Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation.

    Issei Komuro;Youichi Katoh;Toshikazu Kaida;Yoshikazu Shibazaki

  • Endoplasmic Reticulum Stress As a Therapeutic Target in Cardiovascular Disease

    Tetsuo Minamino;Issei Komuro;Masafumi Kitakaze

  • Tbx5 associates with Csx/Nkx2-5 and synergistically promotes cardiomyocyte differentiation

    Yukio Hiroi;Koushirou Monzen;Tooru Hosoda;Hiroki Kasai

Frequent Co-Authors

Ryozo Nagai
Ryozo Nagai Jichi Medical University
Yoshio Yazaki
Yoshio Yazaki University of Tokyo
Yasunobu Hirata
Yasunobu Hirata University of Tokyo
Masatsugu Hori
Masatsugu Hori Osaka University
Mitsuaki Isobe
Mitsuaki Isobe Tokyo Medical and Dental University
Yoshiki Sawa
Yoshiki Sawa Osaka University
Fumimaro Takaku
Fumimaro Takaku University of Tokyo
Hiroyuki Tsutsui
Hiroyuki Tsutsui Kyushu University
Ichiro Manabe
Ichiro Manabe Chiba University
Takashi Kadowaki
Takashi Kadowaki Toranomon Hospital

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