His primary areas of study are Cell biology, Inflammation, Internal medicine, Endocrinology and Adipose tissue. His Cell biology research is multidisciplinary, relying on both Cancer research, Cellular differentiation, Transcription factor, Regulation of gene expression and Adipogenesis. His Cellular differentiation research integrates issues from Molecular biology and Neointima.
His Inflammation research includes elements of Adipokine, Cell adhesion molecule and Pathology. Adipose tissue macrophages is the focus of his Adipose tissue research. His studies deal with areas such as 3T3-L1, Adipocyte, Immune system, Adoptive cell transfer and Cell type as well as Adipose tissue macrophages.
Ichiro Manabe mostly deals with Cell biology, Internal medicine, Endocrinology, Inflammation and Transcription factor. Ichiro Manabe interconnects Fibrosis, Neointima and Vascular smooth muscle, Smooth muscle in the investigation of issues within Cell biology. His Internal medicine study often links to related topics such as Cardiology.
His study of Angiotensin II is a part of Endocrinology. His research in Inflammation intersects with topics in Adipose tissue, Macrophage, Immune system and Pathology. The Adipose tissue study combines topics in areas such as Stromal cell and Obesity.
Cell biology, Inflammation, Macrophage, Internal medicine and Immunology are his primary areas of study. His Cell biology research is multidisciplinary, incorporating perspectives in Fibrosis and Cholesterol, Foam cell, Lipoprotein. His Inflammation research incorporates themes from Cancer, Immune system, Function, Disease and Extracellular matrix.
His study in Immune system is interdisciplinary in nature, drawing from both Adipose tissue, Lipid metabolism, Proinflammatory cytokine and Regulator. Ichiro Manabe has researched Internal medicine in several fields, including Endocrinology and Cardiology. His Immunology study combines topics from a wide range of disciplines, such as Lymphedema and Homeostasis.
His main research concerns Inflammation, Cell biology, Immunology, Molecular biology and Internal medicine. His biological study spans a wide range of topics, including Regulation of gene expression, Macrophage, Immune system and Fatty acid metabolism. The study incorporates disciplines such as Diabetes mellitus, Cancer, Adipose tissue and Disease in addition to Immune system.
His Cell biology research incorporates elements of Fibrosis, Glycolysis, PER2 and Circadian rhythm. His Immunology research includes themes of Vascular endothelial growth factor C, Lymphedema, Edema and Lymphangiogenesis. His Internal medicine study integrates concerns from other disciplines, such as Endocrinology and Adoptive cell transfer.
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CD8 + effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
Satoshi Nishimura;Ichiro Manabe;Mika Nagasaki;Koji Eto.
Nature Medicine (2009)
Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance
Nozomu Kamei;Nozomu Kamei;Kazuyuki Tobe;Ryo Suzuki;Mitsuru Ohsugi.
Journal of Biological Chemistry (2006)
Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine–endothelial cell interactions
Daiji Kawanami;Koji Maemura;Norihiko Takeda;Tomohiro Harada.
Biochemical and Biophysical Research Communications (2004)
Gene Expression in Fibroblasts and Fibrosis: Involvement in Cardiac Hypertrophy
Ichiro Manabe;Takayuki Shindo;Ryozo Nagai.
Circulation Research (2002)
RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock
Jean-Michel Fustin;Masao Doi;Yoshiaki Yamaguchi;Hayashi Hida.
Cell (2013)
Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels.
Satoshi Nishimura;Ichiro Manabe;Mika Nagasaki;Yumiko Hosoya.
Diabetes (2007)
Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation.
Yumiko Oishi;Ichiro Manabe;Kazuyuki Tobe;Kensuke Tsushima.
Cell Metabolism (2005)
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.
Takayuki Shindo;Ichiro Manabe;Yasushi Fukushima;Kazuyuki Tobe.
Nature Medicine (2002)
Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation
Kosei Eguchi;Ichiro Manabe;Yumiko Oishi-Tanaka;Mitsuru Ohsugi.
Cell Metabolism (2012)
Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload
Norifumi Takeda;Ichiro Manabe;Yuichi Uchino;Kosei Eguchi.
Journal of Clinical Investigation (2010)
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