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Biology and Biochemistry

D-Index
92
Citations
25332
World Ranking
2251
National Ranking
136

Medicine

D-Index
92
Citations
25470
World Ranking
11449
National Ranking
336

Overview

Yuichi Oike is affiliated with Kumamoto University in Japan, with a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their work intersects multiple subfields including cardiology and cardiovascular medicine, cancer research, molecular biology, immunology, and physiology.

The primary topics of Oike's research include lipid metabolism and disorders, cancer-related molecular mechanisms, cancer in relation to hypoxia and metabolism, RNA modifications connected to cancer, genetics and aging in model organisms, adipose tissue and metabolism, as well as the interplay between cancer, lipids, and metabolism.

Frequent coauthors collaborating with Oike are:

  • Tsuyoshi Kadomatsu
  • Keishi Miyata
  • Haruki Horiguchi
  • Jun Morinaga
  • Michio Sato

The venues where Oike has published most include:

  • Nature Communications
  • Cancer Research
  • Communications Biology
  • Cancer Science
  • Biochemical and Biophysical Research Communications

Selected recent papers authored or coauthored by Oike reflect a focus on cardiovascular biology, metabolism, and immunology:

  • "Associations of cardiovascular biomarkers and plasma albumin with exceptional survival to the highest ages," 2020, Nature Communications
  • "The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis," 2021, Nature Communications
  • "Prostaglandin E2-EP4 Axis Promotes Lipolysis and Fibrosis in Adipose Tissue Leading to Ectopic Fat Deposition and Insulin Resistance," 2020, Cell Reports
  • "Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia," 2021, Cell Reports Medicine
  • "A circulating subset of iNKT cells mediates antitumor and antiviral immunity," 2022, Science Immunology

Best Publications

  • Mobilization of Endothelial Progenitor Cells in Patients With Acute Myocardial Infarction

    Satoshi Shintani;Toyoaki Murohara;Hisao Ikeda;Takafumi Ueno

  • Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1.

    Masato Iwabu;Toshimasa Yamauchi;Miki Okada-Iwabu;Koji Sato

  • DC-STAMP is essential for cell–cell fusion in osteoclasts and foreign body giant cells

    Mitsuru Yagi;Takeshi Miyamoto;Yumi Sawatani;Katsuya Iwamoto

  • A crucial role for adipose tissue p53 in the regulation of insulin resistance

    Tohru Minamino;Tohru Minamino;Masayuki Orimo;Ippei Shimizu;Takeshige Kunieda

  • Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle

    Tetsuya Kubota;Naoto Kubota;Hiroki Kumagai;Shinichi Yamaguchi

  • Tumour necrosis factor α signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice

    Kengo Tomita;Gen Tamiya;Satoshi Ando;Kayoko Ohsumi

  • The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism

    Tai Hato;Mitsuhisa Tabata;Mitsuhisa Tabata;Yuichi Oike;Yuichi Oike;Yuichi Oike

  • Truncated CBP Protein Leads to Classical Rubinstein—Taybi Syndrome Phenotypes in Mice: Implications for a Dominant-Negative Mechanism

    Yuichi Oike;Akira Hata;Takayoshi Mamiya;Tadashi Kaname

  • Angiopoietin-like Protein 2 Promotes Chronic Adipose Tissue Inflammation and Obesity-Related Systemic Insulin Resistance

    Mitsuhisa Tabata;Tsuyoshi Kadomatsu;Shigetomo Fukuhara;Keishi Miyata

  • Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B.

    Ada Congrains;Kei Kamide;Ryousuke Oguro;Osamu Yasuda

  • Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development

    Ryosuke Tsunematsu;Keiko Nakayama;Yuichi Oike;Masaaki Nishiyama

  • Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation

    Tohru Morisada;Yuichi Oike;Yoshihiro Yamada;Yoshihiro Yamada;Yoshihiro Yamada;Takashi Urano;Takashi Urano;Takashi Urano

  • Angiogenic Role of LYVE-1-positive Macrophages in Adipose Tissue

    Chung Hyun Cho;Chung Hyun Cho;Young Jun Koh;Jinah Han;Hoon Ki Sung

  • Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.

    Tuomas Tammela;Anne Saaristo;Marja Lohela;Tohru Morisada

  • Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression

    Hiromi Yuasa;Yuichi Oike;Atsushi Iwama;Ichiro Nishikata

  • Angiopoietin-related growth factor antagonizes obesity and insulin resistance

    Yuichi Oike;Masaki Akao;Kunio Yasunaga;Toshimasa Yamauchi

  • Inhibition of Angiogenesis and Vascular Leakiness by Angiopoietin-Related Protein 4

    Yasuhiro Ito;Yuichi Oike;Kunio Yasunaga;Koichi Hamada

  • Mice Homozygous for a Truncated Form of CREB-Binding Protein Exhibit Defects in Hematopoiesis and Vasculo-angiogenesis

    Yuichi Oike;Nobuyuki Takakura;Nobuyuki Takakura;Akira Hata;Akira Hata;Tadashi Kaname;Tadashi Kaname

  • The Endoplasmic Reticulum Stress-C/EBP Homologous Protein Pathway-Mediated Apoptosis in Macrophages Contributes to the Instability of Atherosclerotic Plaques

    Hiroto Tsukano;Tomomi Gotoh;Motoyoshi Endo;Keishi Miyata

  • Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-κB pathway

    Norihiro Nagai;Kanako Izumi-Nagai;Yuichi Oike;Takashi Koto

Frequent Co-Authors

Toshio Suda
Toshio Suda National University of Singapore
Kazuo Tsubota
Kazuo Tsubota Keio University
Kimi Araki
Kimi Araki Kumamoto University
Hisao Ogawa
Hisao Ogawa Kumamoto University
Motohiro Takeya
Motohiro Takeya Kumamoto Health Science University
Nobuyuki Takakura
Nobuyuki Takakura Osaka University
Ken Ichi Yamamura
Ken Ichi Yamamura Kumamoto University
Ichiro Manabe
Ichiro Manabe Chiba University
Hiroshi Itoh
Hiroshi Itoh Keio University
Takeshi Miyamoto
Takeshi Miyamoto Kumamoto University

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