Richard R. Tidwell

Overview

Best Publications

• Human African trypanosomiasis: pharmacological re-engagement with a neglected disease

  M P Barrett;D W Boykin;R Brun;R R Tidwell

  440
  Citations

• Structure-In Vitro Activity Relationships of Pentamidine Analogues and Dication-Substituted Bis-Benzimidazoles as New Antifungal Agents

  Maurizio Del Poeta;Wiley A. Schell;Christine C. Dykstra;Susan Jones

  301
  Citations

• Structure, DNA minor groove binding, and base pair specificity of alkyl- and aryl-linked bis(amidinobenzimidazoles) and bis(amidinoindoles)

  Terri A. Fairley;Richard R. Tidwell;Isaac Donkor;Noreen A. Naiman

  291
  Citations

• Extended aromatic furan amidino derivatives as anti-Pneumocystis carinii agents.

  Hopkins Kt;Wilson Wd;Bender Bc;McCurdy Dr

  252
  Citations

• Dicationic diarylfurans as anti-Pneumocystis carinii agents.

  Boykin Dw;Kumar A;Spychala J;Zhou M

  240
  Citations

• Diarylamidine derivatives with one or both of the aryl moieties consisting of an indole or indole-like ring. Inhibitors of arginine-specific esteroproteases

  Richard R Tidwell;J. D. Geratz;O. Dann;G. Volz

  225
  Citations

• Synthesis and Antiprotozoal Activity of Cationic 1,4-Diphenyl-1H-1,2,3-Triazoles

  Stanislav A. Bakunov;Svetlana M. Bakunova;Tanja Wenzler;Maedot Ghebru

  199
  Citations

• 2,5-bis[4-(N-alkylamidino)phenyl]furans as anti-Pneumocystis carinii agents.

  David W. Boykin;Arvind Kumar;Ge Xiao;W. David Wilson

  172
  Citations

• New Treatment Option for Second-Stage African Sleeping Sickness: In Vitro and In Vivo Efficacy of Aza Analogs of DB289

  Tanja Wenzler;David W. Boykin;Mohamed A. Ismail;James Edwin Hall

  166
  Citations

• NOVEL DICATIONIC IMIDAZO[1,2-a]PYRIDINES AND 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2a]PYRIDINES AS ANTIPROTOZOAL AGENTS

  David W. Boykin;Richard R. Tidwell;W. David Wilson;Mohamed A. Ismail

  162
  Citations

• Anti-pneumocystis activity of bis-amidoximes and bis-o-alkylamidoximes prodrugs

  David W. Boykin;Arvind Kumar;James E. Hall;Brendan C. Bender

  153
  Citations

• Structure and DNA binding activity of analogues of 1,5-bis(4-amidinophenoxy)pentane (pentamidine)

  Michael Cory;Richard R. Tidwell;Terri A. Fairley

  150
  Citations

• Accumulation and Intracellular Distribution of Antitrypanosomal Diamidine Compounds DB75 and DB820 in African Trypanosomes

  Amanda M. Mathis;Jacqueline L. Holman;Lisa M. Sturk;Mohamed A. Ismail

  145
  Citations

• Structure-activity studies of dicationically substituted bis-benzimidazoles against Giardia lamblia: correlation of antigiardial activity with DNA binding affinity and giardial topoisomerase II inhibition.

  C. A. Bell;C. C. Dykstra;N. A. Naiman;M. Cory

  144
  Citations

• Prodrugs for amidines: synthesis and anti-Pneumocystis carinii activity of carbamates of 2,5-bis(4-amidinophenyl)furan.

  Syed M. Rahmathullah;James Edwin Hall;Brendan C. Bender;Donald R. McCurdy

  143
  Citations

• Anti-Pneumocystis Activities of Aromatic Diamidoxime Prodrugs

  James Edwin Hall;John E. Kerrigan;Kishore Ramachandran;Brendan C. Bender

  140
  Citations

• Diamidines for human African trypanosomiasis.

  Mary F Paine;Michael Zhuo Wang;Claudia N Generaux;David W Boykin

  140
  Citations

• Strategies for anticoagulation with synthetic protease inhibitors. Xa inhibitors versus thrombin inhibitors.

  R.R Tidwell;W.P Webster;S.R Shaver;J.D Geratz

  139
  Citations

• STRUCTURE-ACTIVITY RELATIONSHIPS OF PENTAMIDINE ANALOGS AGAINST GIARDIA LAMBLIA AND CORRELATION OF ANTIGIARDIAL ACTIVITY WITH DNA-BINDING AFFINITY

  C. A. Bell;M. Cory;T. A. Fairley;J. E. Hall

  129
  Citations

• CYP4F Enzymes Are the Major Enzymes in Human Liver Microsomes That Catalyze the O-Demethylation of the Antiparasitic Prodrug DB289 [2,5-Bis(4-amidinophenyl)furan-bis-O-methylamidoxime]

  Michael Zhuo Wang;Janelle Y. Saulter;Etsuko Usuki;Yen Ling Cheung

  125
  Citations