World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
44
Citations
6638
World Ranking
16915
National Ranking
4178

Overview

Farial A. Tanious is affiliated with Georgia State University in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology. They have contributed to topics including DNA and nucleic acid chemistry, molecular junctions and nanostructures, surface chemistry and catalysis, Trypanosoma species research and implications, advanced biosensing and bioanalysis techniques, and cancer therapeutics and mechanisms.

Their recent publications include the following papers:

  • Unusually Strong Binding to the DNA Minor Groove by a Highly Twisted Benzimidazole Diphenylether: Induced Fit and Bound Water, 2020, OPAL (Open@LaTrobe) (La Trobe University)
  • Diphenyl Furans and Aza Analogs: Effects of Structural Modification on In Vitro Activity, DNA Binding, and Accumulation and Distribution in Trypanosomes, 2021, UNC Libraries
  • A High-Throughput, High-Resolution Strategy for the Study of Site-Selective DNA Binding Agents: Analysis of a "Highly Twisted" Benzimidazole-Diamidine, 2020, OPAL (Open@LaTrobe) (La Trobe University)
  • Antiparasitic compounds that target DNA, 2020, UNC Libraries

Frequent collaborators in their work include Richard R. Tidwell, W. David Wilson, Kristie D. Goodwin, Mark A. Lewis, and Eric C. Long.

Tanious has published extensively in venues such as OPAL (Open@LaTrobe) (La Trobe University) and UNC Libraries.

Best Publications

  • DAPI (4',6-diamidino-2-phenylindole) binds differently to DNA and RNA: minor-groove binding at AT sites and intercalation at AU sites.

    Tanious Fa;Veal Jm;Buczak H;Ratmeyer Ls

  • DNA sequence dependent binding modes of 4',6-diamidino-2-phenylindole (DAPI).

    W D Wilson;F A Tanious;H J Barton;R L Jones

  • Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.

    Michael J B Moore;Christoph M Schultes;Javier Cuesta;Francisco Cuenca

  • Antiparasitic compounds that target DNA.

    W. David Wilson;Farial A. Tanious;Amanda Mathis;Denise Tevis

  • Biosensor-surface plasmon resonance: quantitative analysis of small molecule-nucleic acid interactions.

    Binh Nguyen;Farial A. Tanious;W. David Wilson

  • Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.

    R John Harrison;Javier Cuesta;Gianni Chessari;Martin A Read

  • Structure-specific recognition of quadruplex DNA by organic cations: influence of shape, substituents and charge.

    Elizabeth W. White;Farial Tanious;Mohamed A. Ismail;Anthony P. Reszka

  • Dications That Target the DNA Minor Groove: Compound Design and Preparation, DNA Interactions, Cellular Distribution and Biological Activity

    W. David Wilson;Binh Nguyen;Farial A. Tanious;Amanda Mathis

  • A thermodynamic and structural analysis of DNA minor-groove complex formation.

    Mazur S;Tanious Fa;Ding D;Kumar A

  • Binding of 4',6-diamidino-2-phenylindole (DAPI) to GC and mixed sequences in DNA: intercalation of a classical groove-binding molecule

    W. David Wilson;Farial A. Tanious;Henryk J. Barton;Robert L. Jones

  • DNA triple-helix specific intercalators as antigene enhancers : unfused aromatic cations

    W. David Wilson;Farial A. Tanious;Shaikh Mizan;Shijie Yao

  • NOVEL DICATIONIC IMIDAZO[1,2-a]PYRIDINES AND 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2a]PYRIDINES AS ANTIPROTOZOAL AGENTS

    David W. Boykin;Richard R. Tidwell;W. David Wilson;Mohamed A. Ismail

  • Synthesis and antiprotozoal activity of aza-analogues of furamidine.

    Mohamed A. Ismail;Reto Brun;Judy D. Easterbrook;Farial A. Tanious

  • Kinetic and equilibrium analysis of a threading intercalation mode: DNA sequence and ion effects.

    F. A. Tanious;Shau-Fong Yen;W. D. Wilson

  • A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity.

    C.A Laughton;F Tanious;C.M Nunn;D.W Boykin

  • DNA sequence dependent monomer-dimer binding modulation of asymmetric benzimidazole derivatives.

    Farial A. Tanious;Donald Hamelberg;Christian Bailly;Agnieska Czarny

  • Effects of compound structure on carbazole dication-DNA complexes: tests of the minor-groove complex models.

    F A Tanious;D Ding;D A Patrick;D A Patrick;C Bailly

  • Biosensor-surface plasmon resonance methods for quantitative analysis of biomolecular interactions.

    Farial A Tanious;Binh Nguyen;W David Wilson

  • Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines.

    Mohamed A. Ismail;Reem K. Arafa;Tanja Wenzler;Reto Brun

  • Synthesis and DNA interactions of benzimidazole dications which have activity against opportunistic infections.

    Unknown

  • Nucleic Acid Interactions of Unfused Aromatic Cations: Evaluation of Proposed Minor-Groove, Major-Groove, and Intercalation Binding Modes

    W. David Wilson;Farial A. Tanious;Daoyuan Ding;Arvind Kumar

Frequent Co-Authors

W. David Wilson
W. David Wilson Georgia State University
David W. Boykin
David W. Boykin Georgia State University
Lucjan Strekowski
Lucjan Strekowski Georgia State University
Richard R. Tidwell
Richard R. Tidwell University of North Carolina at Chapel Hill
Reto Brun
Reto Brun University of Basel
Stephen Neidle
Stephen Neidle University College London
Christian Bailly
Christian Bailly Université Catholique de Louvain
Gerald Zon
Gerald Zon TriLink BioTechnologies (United States)
Wiley A. Schell
Wiley A. Schell Duke University
John R. Perfect
John R. Perfect Duke University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens numerous avenues for careers that blend science with real-world applications. One growing field is forensic science, where a strong chemistry background is essential. For those interested in entry-level roles, becoming a forensic autopsy technician can be a rewarding start, combining chemistry knowledge with anatomy and pathology.

Many aspiring professionals pursue formal education online to fit their schedules. You can find the forensic science degree online, which equips students with crucial skills ranging from chemical analysis to crime scene investigation. Complementing this, there are specialized forensic psychology master's programs online that explore the psychological aspects behind criminal behaviors, ideal for those interested in a multidisciplinary approach.

Career prospects in forensic science are promising, with competitive salaries reflecting expertise and experience. To understand more about potential earnings and job opportunities, reviewing the forensic science degree salary information can help you make informed decisions about your education and career path.

Best Scientists Citing Farial A. Tanious