World's Best Scientists 2026 revealed!
Marie-Paule Teulade-Fichou

Marie-Paule Teulade-Fichou

D-Index & Metrics

Chemistry

D-Index
60
Citations
12750
World Ranking
9702
National Ranking
347

Biology and Biochemistry

D-Index
62
Citations
13436
World Ranking
10825
National Ranking
390

Overview

Marie-Paule Teulade-Fichou is affiliated with the University of Paris-Saclay in France. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a particular focus on molecular biology as reflected in 56 publications. Other areas of study include oncology, radiology, nuclear medicine and imaging, materials chemistry, and infectious diseases.

Their main topics of work cover a range of biochemical and molecular processes. These include DNA and nucleic acid chemistry, advanced biosensing and bioanalysis techniques, RNA interference and gene delivery, RNA and protein synthesis mechanisms, RNA modifications and cancer, monoclonal and polyclonal antibodies research, and cancer-related gene regulation.

Marie-Paule Teulade-Fichou has contributed extensively to scientific literature, including several recent papers such as:

  • SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction (2021) published in Nucleic Acids Research
  • A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution (2020) published in eLife
  • Phen-DC3 Induces Refolding of Human Telomeric DNA into a Chair-Type Antiparallel G-Quadruplex through Ligand Intercalation (2022) published in Angewandte Chemie International Edition
  • Nucleolin Discriminates Drastically between Long-Loop and Short-Loop Quadruplexes (2020) published in Biochemistry
  • BrdU immuno-tagged G-quadruplex ligands: a new ligand-guided immunofluorescence approach for tracking G-quadruplexes in cells (2021) published in Nucleic Acids Research

The venues where they frequently publish include:

  • Nucleic Acids Research
  • ChemBioChem
  • Journal of Biomedical Science
  • Angewandte Chemie International Edition
  • eLife

Collaboration is a significant aspect of their work, with frequent co-authors being Anton Granzhan, Claire Beauvineau, Marc Blondel, Sophie Bombard, and Rodrigo Prado Martins.

Best Publications

  • A hitchhiker's guide to G-quadruplex ligands

    David Monchaud;Marie-Paule Teulade-Fichou

  • Natural and pharmacological regulation of telomerase

    Jean-Louis Mergny;Jean-François Riou;Patrick Mailliet;Marie-Paule Teulade-Fichou

  • Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

    Anne De Cian;Elsa Delemos;Jean-Louis Mergny;Marie-Paule Teulade-Fichou

  • Fluorescence-based melting assays for studying quadruplex ligands

    Anne De Cian;Lionel Guittat;Markus Kaiser;Barbara Saccà

  • Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.

    Jean-Louis Mergny;Laurent Lacroix;Marie-Paule Teulade-Fichou;Candide Hounsou

  • G-quadruplex-induced instability during leading-strand replication

    Judith Lopes;Aurèle Piazza;Rodrigo Bermejo;Barry Kriegsman

  • Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

    Anne De Cian;Gael Cristofari;Patrick Reichenbach;Elsa De Lemos

  • Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders

    D. Monchaud;C. Allain;H. Bertrand;N. Smargiasso

  • G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms

    Virginie Marcel;Virginie Marcel;Phong Lan Thao Tran;Charlotte Sagne;Charlotte Sagne;Ghyslaine Martel-Planche

  • Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands.

    David Monchaud;Clémence Allain;Marie-Paule Teulade-Fichou

  • Selective recognition of g-quadruplex telomeric DNA by a bis(quinacridine) macrocycle

    Marie-Paule Teulade-Fichou;Carolina Carrasco;Lionel Guittat;Christian Bailly

  • Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC3

    Wan Jun Chung;Brahim Heddi;Florian Hamon;Marie-Paule Teulade-Fichou

  • A G-quadruplex structure within the 5′-UTR of TRF2 mRNA represses translation in human cells

    Dennis Gomez;Aurore Guédin;Jean-Louis Mergny;Bernard Salles

  • Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae

    Aurèle Piazza;Jean-Baptiste Boulé;Judith Lopes;Katie Mingo

  • Engineering Bisquinolinium/Thiazole Orange Conjugates for Fluorescent Sensing of G‐Quadruplex DNA

    Peng Yang;Anne De Cian;Marie-Paule Teulade-Fichou;Jean-Louis Mergny

  • The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes.

    Hélène Bertrand;David Monchaud;Anne De Cian;Régis Guillot

  • Involvement of G-quadruplex regions in mammalian replication origin activity

    Paulina Prorok;Marie Artufel;Antoine Aze;Philippe Coulombe

  • Stabilization and structure of telomeric and c-myc region intramolecular G-quadruplexes: the role of central cations and small planar ligands.

    Valérie Gabelica;Erin Shammel Baker;Marie-Paule Teulade-Fichou;Edwin De Pauw

  • Visualizing the Quadruplex: From Fluorescent Ligands to Light-Up Probes

    Eric Largy;Anton Granzhan;Florian Hamon;Daniela Verga

  • Synthetic strategies to derivatizable triphenylamines displaying high two-photon absorption.

    Rémy Lartia;Clémence Allain;Guillaume Bordeau;Falk Schmidt

  • A metal-mediated conformational switch controls G-quadruplex binding affinity.

    David Monchaud;Peng Yang;Laurent Lacroix;Marie-Paule Teulade-Fichou

Frequent Co-Authors

Jean-Marie Lehn
Jean-Marie Lehn University of Strasbourg
Valérie Gabelica
Valérie Gabelica University of Bordeaux
Jean-François Riou
Jean-François Riou French National Museum of Natural History
Régis Guillot
Régis Guillot University of Paris-Saclay
Olivier Baudoin
Olivier Baudoin University of Basel
Markus Kaiser
Markus Kaiser University of Duisburg-Essen
Edwin De Pauw
Edwin De Pauw University of Liège
Claude Hélène
Claude Hélène Grenoble Alpes University
Elmar G. Weinhold
Elmar G. Weinhold RWTH Aachen University

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