D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 47 Citations 7,168 303 World Ranking 11954 National Ranking 950

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Enzyme
  • Gene

Kazuo Nagasawa mostly deals with Organic chemistry, Stereochemistry, Guanidine, Total synthesis and Thiourea. His study in Nitroaldol reaction, Bifunctional and Stereoselectivity is done as part of Organic chemistry. His Stereochemistry study integrates concerns from other disciplines, such as G-quadruplex, Biological activity, Biochemistry and Cycloaddition.

His Guanidine study deals with Enantioselective synthesis intersecting with Phase-transfer catalyst, Nitro and Diamine. The study incorporates disciplines such as Sodium channel, Overman rearrangement, Inorganic chemistry, Aminal and Sigmatropic reaction in addition to Total synthesis. His Thiourea research is multidisciplinary, relying on both Organocatalysis, Medicinal chemistry and Catalysis, Baylis–Hillman reaction.

His most cited work include:

  • Development of bis-thiourea-type organocatalyst for asymmetric Baylis–Hillman reaction (195 citations)
  • Guanidine‐Thiourea Bifunctional Organocatalyst for the Asymmetric Henry (Nitroaldol) Reaction (185 citations)
  • C2‐Symmetric Chiral Pentacyclic Guanidine: A Phase‐Transfer Catalyst for the Asymmetric Alkylation of tert‐Butyl Glycinate Schiff Base (127 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Stereochemistry, Organic chemistry, Guanidine, Catalysis and G-quadruplex. His work on Total synthesis as part of general Stereochemistry research is frequently linked to Side chain, bridging the gap between disciplines. His study in Enantioselective synthesis, Organocatalysis and Yield are all subfields of Organic chemistry.

In his research on the topic of Guanidine, Thiourea, Nitroaldol reaction and Tetralone is strongly related with Bifunctional. He interconnects Combinatorial chemistry and Medicinal chemistry in the investigation of issues within Catalysis. The G-quadruplex study combines topics in areas such as Telomere, Biophysics and Ligand.

He most often published in these fields:

  • Stereochemistry (36.03%)
  • Organic chemistry (25.42%)
  • Guanidine (19.27%)

What were the highlights of his more recent work (between 2016-2021)?

  • G-quadruplex (14.53%)
  • Stereochemistry (36.03%)
  • Telomestatin (7.26%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include G-quadruplex, Stereochemistry, Telomestatin, DNA and Enantioselective synthesis. His study in G-quadruplex is interdisciplinary in nature, drawing from both Biophysics, Nucleic acid, Computational biology and Binding site. His Stereochemistry study frequently links to other fields, such as Regioselectivity.

Kazuo Nagasawa combines subjects such as Molecule, Stacking and Helicase with his study of Telomestatin. Kazuo Nagasawa has researched Enantioselective synthesis in several fields, including Bifunctional and Guanidine. His study with Catalysis involves better knowledge in Organic chemistry.

Between 2016 and 2021, his most popular works were:

  • Vitamin D Metabolite, 25-Hydroxyvitamin D, Regulates Lipid Metabolism by Inducing Degradation of SREBP/SCAP (41 citations)
  • Structure-Dependent Binding of hnRNPA1 to Telomere RNA. (27 citations)
  • Targeting STUB1–tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk (26 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Enzyme
  • Gene

His main research concerns G-quadruplex, Telomestatin, Stereochemistry, Computational biology and Biophysics. Kazuo Nagasawa has included themes like Transcription, E2F1, Mutant, Coding region and Genomic imprinting in his G-quadruplex study. The various areas that he examines in his Telomestatin study include Stacking, DNA damage, Binding site and A-DNA.

His research in Stereochemistry intersects with topics in Regioselectivity and Enantioselective synthesis. His work deals with themes such as Intramolecular force, Isomerization and Coupling reaction, which intersect with Enantioselective synthesis. His Total synthesis research incorporates themes from Bifunctional, Kinetic resolution and Tetralones.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Development of bis-thiourea-type organocatalyst for asymmetric Baylis–Hillman reaction

Yoshihiro Sohtome;Aya Tanatani;Yuichi Hashimoto;Kazuo Nagasawa.
Tetrahedron Letters (2004)

310 Citations

Guanidine-Thiourea Bifunctional Organocatalyst for the Asymmetric Henry (Nitroaldol) Reaction

Yoshihiro Sohtome;Yuichi Hashimoto;Kazuo Nagasawa.
Advanced Synthesis & Catalysis (2005)

284 Citations

Total Synthesis of Pinnatoxin A

John A. McCauley;Kazuo Nagasawa;Peter A. Lander;Steven G. Mischke.
Journal of the American Chemical Society (1998)

206 Citations

Diastereoselective and Enantioselective Henry (Nitroaldol) Reaction Utilizing a Guanidine-Thiourea Bifunctional Organocatalyst

Yoshihiro Sohtome;Yuichi Hashimoto;Kazuo Nagasawa.
European Journal of Organic Chemistry (2006)

201 Citations

C2‐Symmetric Chiral Pentacyclic Guanidine: A Phase‐Transfer Catalyst for the Asymmetric Alkylation of tert‐Butyl Glycinate Schiff Base

Tetsuya Kita;Angelina Georgieva;Yuichi Hashimoto;Tadashi Nakata.
Angewandte Chemie (2002)

198 Citations

Entropy‐Controlled Catalytic Asymmetric 1,4‐Type Friedel–Crafts Reaction of Phenols Using Conformationally Flexible Guanidine/Bisthiourea Organocatalyst

Yoshihiro Sohtome;Bongki Shin;Natsuko Horitsugi;Rika Takagi.
Angewandte Chemie (2010)

182 Citations

Organocatalytic Asymmetric Nitroaldol Reaction: Cooperative Effects of Guanidine and Thiourea Functional Groups

Yoshihiro Sohtome;Nobuko Takemura;Keisuke Takada;Rika Takagi.
Chemistry-an Asian Journal (2007)

166 Citations

Solution Structure of an Intramolecular (3 + 1) Human Telomeric G-Quadruplex Bound to a Telomestatin Derivative

Wan Jun Chung;Brahim Heddi;Masayuki Tera;Keisuke Iida.
Journal of the American Chemical Society (2013)

166 Citations

Solvent-dependent enantiodivergent Mannich-type reaction: utilizing a conformationally flexible guanidine/bisthiourea organocatalyst.

Yoshihiro Sohtome;Shinji Tanaka;Keisuke Takada;Takahisa Yamaguchi.
Angewandte Chemie (2010)

163 Citations

Rif1 binds to G quadruplexes and suppresses replication over long distances

Yutaka Kanoh;Seiji Matsumoto;Rino Fukatsu;Naoko Kakusho.
Nature Structural & Molecular Biology (2015)

162 Citations

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