Makoto Makishima

Overview

Best Publications

• Increased oxidative stress in obesity and its impact on metabolic syndrome

  Shigetada Furukawa;Takuya Fujita;Michio Shimabukuro;Masanori Iwaki

  6407
  Citations

• Identification of a Nuclear Receptor for Bile Acids

  Makoto Makishima;Arthur Y. Okamoto;Joyce J. Repa;Hua Tu

  3003
  Citations

• Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.

  Atsunori Fukuhara;Morihiro Matsuda;Masako Nishizawa;Katsumori Segawa

  2728
  Citations

• Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors.

  Timothy T. Lu;Makoto Makishima;Joyce J. Repa;Kristina Schoonjans

  1690
  Citations

• Vitamin D Receptor As an Intestinal Bile Acid Sensor

  Makoto Makishima;Timothy T. Lu;Wen Xie;G. Kerr Whitfield

  1356
  Citations

• Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors

  Masanori Iwaki;Morihiro Matsuda;Norikazu Maeda;Tohru Funahashi

  1045
  Citations

• Human Bile Salt Export Pump Promoter Is Transactivated by the Farnesoid X Receptor/Bile Acid Receptor

  Meenakshisundaram Ananthanarayanan;Natarajan V. Balasubramanian;Makoto Makishima;David J. Mangelsdorf

  937
  Citations

• The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp.

  Lee A. Denson;Ekkehard Sturm;Wihelma Echevarria;Tracy L. Zimmerman

  540
  Citations

• The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway

  Keith D. Baker;Lisa M. Shewchuk;Tatiana Kozlova;Makoto Makishima;Makoto Makishima

  291
  Citations

• Induction of Intestinal ATP-binding Cassette Transporters by a Phytosterol-derived Liver X Receptor Agonist

  Emi Kaneko;Morihiro Matsuda;Yukio Yamada;Yoji Tachibana

  285
  Citations

• Musclin, a novel skeletal muscle-derived secretory factor.

  Hitoshi Nishizawa;Hitoshi Nishizawa;Morihiro Matsuda;Morihiro Matsuda;Yukio Yamada;Kenichiro Kawai

  210
  Citations

• Selective activation of vitamin D receptor by lithocholic acid acetate, a bile acid derivative

  Ryutaro Adachi;Yoshio Honma;Hiroyuki Masuno;Katsuyoshi Kawana;Katsuyoshi Kawana

  203
  Citations

• Nuclear receptors as targets for drug development: regulation of cholesterol and bile acid metabolism by nuclear receptors.

  Makoto Makishima

  190
  Citations

• Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor

  Toshimori Inaba;Morihiro Matsuda;Morihiro Matsuda;Mitsuru Shimamura;Norihide Takei

  186
  Citations

• Diosgenin, the Main Aglycon of Fenugreek, Inhibits LXRα Activity in HepG2 Cells and Decreases Plasma and Hepatic Triglycerides in Obese Diabetic Mice

  Taku Uemura;Tsuyoshi Goto;Min‑Sook Kang;Noriko Mizoguchi

  162
  Citations

• Sulfonylurea Agents Exhibit Peroxisome Proliferator-activated Receptor γ Agonistic Activity

  Shuichi Fukuen;Masanori Iwaki;Atsutaka Yasui;Makoto Makishima

  150
  Citations

• Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes.

  Mitsuru Shimamura;Morihiro Matsuda;Sachiko Kobayashi;Yosuke Ando

  145
  Citations

• Lithocholic acid derivatives act as selective vitamin D receptor modulators without inducing hypercalcemia.

  Michiyasu Ishizawa;Manabu Matsunawa;Ryutaro Adachi;Shigeyuki Uno

  142
  Citations

• Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARγ pathway

  Masanobu Kawai;Noriyuki Namba;Sotaro Mushiake;Yuri Etani

  132
  Citations

• Visfatin : A protein secreted by visceral fat that mimics the effects of insulin

  Atsunori Fukuhara;Morihiro Matsuda;Masako Nishizawa;Katsumori Segawa

  11
  Citations