What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Internal medicine
His main research concerns Biochemistry, Nuclear receptor, Internal medicine, Endocrinology and Bile acid.
His work carried out in the field of Biochemistry brings together such families of science as Molecular biology and Cell biology.
His Nuclear receptor research is multidisciplinary, incorporating perspectives in Calcitriol receptor, Receptor, Signal transduction and Coactivator.
His work on Myocyte, Glimepiride and Thyroid hormone receptor as part of general Endocrinology study is frequently linked to C2C12 and Signal peptide, bridging the gap between disciplines.
His work is dedicated to discovering how Adipose tissue, Adipokine are connected with Oxidative stress, NADPH oxidase, Metabolic syndrome, Reactive oxygen species and Steatosis and other disciplines.
His G protein-coupled bile acid receptor research includes themes of Farnesoid X receptor and Cholestasis.
His most cited work include:
- Increased oxidative stress in obesity and its impact on metabolic syndrome (3709 citations)
- Identification of a Nuclear Receptor for Bile Acids (2013 citations)
- Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. (1580 citations)
What are the main themes of his work throughout his whole career to date?
Makoto Makishima spends much of his time researching Biochemistry, Nuclear receptor, Internal medicine, Calcitriol receptor and Receptor.
His Nuclear receptor research incorporates themes from Coactivator, Transactivation, Signal transduction, Steroid and Pharmacology.
The study incorporates disciplines such as Gastroenterology, Endocrinology and Oncology in addition to Internal medicine.
Adipose tissue and Insulin are the primary areas of interest in his Endocrinology study.
His work deals with themes such as Calcium metabolism and Lithocholic acid, Bile acid, which intersect with Calcitriol receptor.
His work investigates the relationship between Receptor and topics such as Liver X receptor that intersect with problems in Cell biology, Transrepression and Lipid metabolism.
He most often published in these fields:
- Biochemistry (30.36%)
- Nuclear receptor (27.39%)
- Internal medicine (24.75%)
What were the highlights of his more recent work (between 2015-2021)?
- Internal medicine (24.75%)
- Calcitriol receptor (23.10%)
- Receptor (22.77%)
In recent papers he was focusing on the following fields of study:
Makoto Makishima focuses on Internal medicine, Calcitriol receptor, Receptor, Liver X receptor and Cell biology.
His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology, Endocrinology and Oncology.
As a member of one scientific family, Makoto Makishima mostly works in the field of Endocrinology, focusing on Immune system and, on occasion, Cytokine.
The various areas that Makoto Makishima examines in his Calcitriol receptor study include Calcium metabolism, Lithocholic acid and Molecular biology.
Receptor is a subfield of Biochemistry that he investigates.
His Liver X receptor study necessitates a more in-depth grasp of Nuclear receptor.
Between 2015 and 2021, his most popular works were:
- Liver X receptors regulate hepatic F4/80 + CD11b+ Kupffer cells/macrophages and innate immune responses in mice. (22 citations)
- Peroxisome proliferator-activated receptor agonists and antagonists: a patent review (2014-present) (17 citations)
- Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice. (17 citations)
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