World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
106
Citations
43271
World Ranking
1147
National Ranking
683

Research.com Recognitions

  • 2019 - Member of the National Academy of Sciences

Overview

David D. Moore is affiliated with the University of California, Berkeley in the United States. Their research spans multiple fields primarily within Medicine and Biochemistry, Genetics and Molecular Biology. The main subfields of their work include Molecular Biology, Physiology, Epidemiology, Oncology, and Immunology.

The scientist's research topics focus on areas such as:

  • Adipose Tissue and Metabolism
  • Drug Transport and Resistance Mechanisms
  • Liver Disease Diagnosis and Treatment
  • Lipid Metabolism and Biosynthesis
  • Epigenetics and DNA Methylation
  • Peroxisome Proliferator-Activated Receptors
  • Adipokines, Inflammation, and Metabolic Diseases

Frequent venues for their publications include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Nature Communications
  • Journal of Clinical Investigation
  • Journal of Hepatology

David D. Moore has collaborated repeatedly with several co-authors, notably:

  • Kang Ho Kim
  • Sean M. Hartig
  • Aaron R. Cox
  • Bingning Dong
  • Pradip Saha

Some of the recent scientific papers authored include:

  • Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice, 2020, Autophagy
  • CAR directs T cell adaptation to bile acids in the small intestine, 2021, Nature
  • FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis, 2020, Journal of Hepatology
  • Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis, 2022, Proceedings of the National Academy of Sciences
  • Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood, 2020, Nature Communications

In 2019, David D. Moore was recognized as a Member of the National Academy of Sciences.

Best Publications

  • Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

    Derek J. Parks;Steven G. Blanchard;Randy K. Bledsoe;Gyan Chandra

  • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    Adrian Ally;Miruna Balasundaram;Rebecca Carlsen;Eric Chuah

  • Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c.

    Mitsuhiro Watanabe;Sander M. Houten;Li Wang;Antonio Moschetta

  • Human growth hormone as a reporter gene in regulation studies employing transient gene expression.

    R F Selden;K B Howie;M E Rowe;H M Goodman

  • Preparation and Analysis of DNA

    David D. Moore;Dennis Dowhan

  • Nutrient-sensing nuclear receptors coordinate autophagy

    Jae Man Lee;Martin Wagner;Rui Xiao;Kang Ho Kim

  • Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

    Katia Georgopoulos;David D. Moore;Bruce Derfler

  • TWO CLASSES OF PROTEINS DEPENDENT ON EITHER THE PRESENCE OR ABSENCE OF THYROID HORMONE FOR INTERACTION WITH THE THYROID HORMONE RECEPTOR

    Jae Woon Lee;Hueng Sik Choi;Jeno Gyuris;Roger Brent

  • Identification of a thyroid hormone receptor that is pituitary-specific.

    RA Hodin;MA Lazar;BI Wintman;DS Darling

  • Interaction of thyroid-hormone receptor with a conserved transcriptional mediator.

    Jae Woon Lee;Fergus Ryan;Jonathan C. Swaffield;Stephen A. Johnston

  • Spontaneous Development of Liver Tumors in the Absence of the Bile Acid Receptor Farnesoid X Receptor

    Fan Yang;Xiongfei Huang;Xiongfei Huang;Tangsheng Yi;Yun Yen

  • Redundant Pathways for Negative Feedback Regulation of Bile Acid Production

    Li Wang;Yoon-Kwang Lee;Donnie Bundman;Yunqing Han

  • The Xenobiotic Compound 1,4-Bis(2-(3,5-Dichloropyridyloxy))Benzene Is an Agonist Ligand for the Nuclear Receptor CAR

    Iphigenia Tzameli;Pavlos Pissios;Erin G. Schuetz;David D. Moore

  • Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing.

    Koenig Rj;Lazar Ma;Hodin Ra;Brent Ga

  • Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

    Wendong Huang;Jun Zhang;Steven S. Chua;Mohammed Qatanani

  • Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis.

    Nicole M. Kettner;Horatio Voicu;Milton J. Finegold;Cristian Coarfa

  • FXR: a metabolic regulator and cell protector.

    Yan-Dong Wang;Wei-Dong Chen;David D Moore;Wendong Huang

  • Modulation of Acetaminophen-Induced Hepatotoxicity by the Xenobiotic Receptor CAR

    Jun Zhang;Wendong Huang;Steven S. Chua;Ping Wei

  • The Farnesoid X-activated Receptor Mediates Bile Acid Activation of Phospholipid Transfer Protein Gene Expression *

    Nancy L. Urizar;Dennis H. Dowhan;David D. Moore

  • Disrupting Circadian Homeostasis of Sympathetic Signaling Promotes Tumor Development in Mice

    Susie Lee;Lawrence A. Donehower;Alan J. Herron;David D. Moore

Frequent Co-Authors

Geoffrey D. Robson
Geoffrey D. Robson University of Manchester
Anthony P. J. Trinci
Anthony P. J. Trinci University of Manchester
Li Wang
Li Wang Yale University
Milton J. Finegold
Milton J. Finegold Baylor College of Medicine
Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Chad J. Creighton
Chad J. Creighton Baylor College of Medicine
Bert W. O'Malley
Bert W. O'Malley Baylor College of Medicine
Cristian Coarfa
Cristian Coarfa Baylor College of Medicine
Michael J. Krashes
Michael J. Krashes National Institutes of Health
Howard M. Goodman
Howard M. Goodman Harvard University

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