2019 - Member of the National Academy of Sciences
David D. Moore spends much of his time researching Nuclear receptor, Endocrinology, Internal medicine, Constitutive androstane receptor and Receptor. His work carried out in the field of Nuclear receptor brings together such families of science as Bile acid, Hepatocyte, Transactivation, Molecular biology and Regulator. His Bile acid study combines topics from a wide range of disciplines, such as Farnesoid X receptor, Pregnane X receptor and Cholestasis.
His Endocrinology research is multidisciplinary, incorporating perspectives in Regulation of gene expression, Liver X receptor beta and Cell biology. His Constitutive androstane receptor study integrates concerns from other disciplines, such as Jaundice, Sulfation, Xenobiotic, Bilirubin and Lithocholic acid. His Receptor research is multidisciplinary, incorporating elements of Hormone response element and Pharmacology.
Internal medicine, Endocrinology, Nuclear receptor, Receptor and Constitutive androstane receptor are his primary areas of study. Internal medicine is closely attributed to Gastroenterology in his work. In his study, Orphan receptor and Liver receptor homolog-1 is inextricably linked to Small heterodimer partner, which falls within the broad field of Endocrinology.
His work deals with themes such as Molecular biology, Cancer research, Cell biology and Transactivation, which intersect with Nuclear receptor. The concepts of his Constitutive androstane receptor study are interwoven with issues in Gene expression, Xenobiotic, Cytochrome P450, Pregnane X receptor and Pharmacology. His biological study spans a wide range of topics, including Farnesoid X receptor and Cholestasis.
David D. Moore mostly deals with Internal medicine, Endocrinology, Cell biology, Cancer research and Constitutive androstane receptor. His Internal medicine study frequently draws connections between related disciplines such as Gastroenterology. His research on Endocrinology often connects related topics like Nuclear receptor.
His Cell biology research incorporates elements of Autophagy, Small intestine, Epigenomics, Gene and Enterohepatic circulation. His Cancer research research includes themes of Cancer, Protein kinase B, Inflammatory bowel disease and MAPK/ERK pathway. As a part of the same scientific family, David D. Moore mostly works in the field of Constitutive androstane receptor, focusing on Cytokine and, on occasion, Cytotoxic T cell.
His main research concerns Cell biology, Internal medicine, Cancer research, Autophagy and Heart failure. David D. Moore has included themes like White Adipocytes, Inflammasome, Liver cell, Gene product and Cell fate determination in his Cell biology study. His Endocrinology research extends to the thematically linked field of Internal medicine.
His studies deal with areas such as Proinflammatory cytokine, Inflammation and microRNA as well as Endocrinology. His work on Hepatocellular carcinoma as part of general Cancer research study is frequently connected to TGF alpha, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Autophagy research incorporates themes from Body weight and Brown adipose tissue, Brown Adipocytes.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Redundant Pathways for Negative Feedback Regulation of Bile Acid Production
Li Wang;Yoon-Kwang Lee;Donnie Bundman;Yunqing Han.
Developmental Cell (2002)
The Xenobiotic Compound 1,4-Bis(2-(3,5-Dichloropyridyloxy))Benzene Is an Agonist Ligand for the Nuclear Receptor CAR
Iphigenia Tzameli;Pavlos Pissios;Erin G. Schuetz;David D. Moore.
Molecular and Cellular Biology (2000)
Preparation and Analysis of DNA
David D. Moore;Dennis Dowhan.
Current Protocols in Molecular Biology (2002)
Induction of bilirubin clearance by the constitutive androstane receptor (CAR)
Wendong Huang;Jun Zhang;Steven S. Chua;Mohammed Qatanani.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Spontaneous Development of Liver Tumors in the Absence of the Bile Acid Receptor Farnesoid X Receptor
Fan Yang;Xiongfei Huang;Xiongfei Huang;Tangsheng Yi;Yun Yen.
Cancer Research (2007)
Modulation of Acetaminophen-Induced Hepatotoxicity by the Xenobiotic Receptor CAR
Jun Zhang;Wendong Huang;Steven S. Chua;Ping Wei.
The Farnesoid X-activated Receptor Mediates Bile Acid Activation of Phospholipid Transfer Protein Gene Expression *
Nancy L. Urizar;Dennis H. Dowhan;David D. Moore.
Journal of Biological Chemistry (2000)
Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor.
Wendong Huang;Jun Zhang;Michele Washington;Jun Liu;Jun Liu.
Molecular Endocrinology (2005)
Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor.
R J Koenig;R L Warne;G A Brent;J W Harney.
Proceedings of the National Academy of Sciences of the United States of America (1988)
Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response
P Wei;J Zhang;D H Dowhan;Y Han.
Pharmacogenomics Journal (2002)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: