D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 73 Citations 16,812 233 World Ranking 3762 National Ranking 1921

Research.com Recognitions

Awards & Achievements

2019 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

David D. Moore spends much of his time researching Nuclear receptor, Endocrinology, Internal medicine, Constitutive androstane receptor and Receptor. His work carried out in the field of Nuclear receptor brings together such families of science as Bile acid, Hepatocyte, Transactivation, Molecular biology and Regulator. His Bile acid study combines topics from a wide range of disciplines, such as Farnesoid X receptor, Pregnane X receptor and Cholestasis.

His Endocrinology research is multidisciplinary, incorporating perspectives in Regulation of gene expression, Liver X receptor beta and Cell biology. His Constitutive androstane receptor study integrates concerns from other disciplines, such as Jaundice, Sulfation, Xenobiotic, Bilirubin and Lithocholic acid. His Receptor research is multidisciplinary, incorporating elements of Hormone response element and Pharmacology.

His most cited work include:

  • Preparation and Analysis of DNA (420 citations)
  • Redundant Pathways for Negative Feedback Regulation of Bile Acid Production (398 citations)
  • The Xenobiotic Compound 1,4-Bis(2-(3,5-Dichloropyridyloxy))Benzene Is an Agonist Ligand for the Nuclear Receptor CAR (343 citations)

What are the main themes of his work throughout his whole career to date?

Internal medicine, Endocrinology, Nuclear receptor, Receptor and Constitutive androstane receptor are his primary areas of study. Internal medicine is closely attributed to Gastroenterology in his work. In his study, Orphan receptor and Liver receptor homolog-1 is inextricably linked to Small heterodimer partner, which falls within the broad field of Endocrinology.

His work deals with themes such as Molecular biology, Cancer research, Cell biology and Transactivation, which intersect with Nuclear receptor. The concepts of his Constitutive androstane receptor study are interwoven with issues in Gene expression, Xenobiotic, Cytochrome P450, Pregnane X receptor and Pharmacology. His biological study spans a wide range of topics, including Farnesoid X receptor and Cholestasis.

He most often published in these fields:

  • Internal medicine (36.09%)
  • Endocrinology (30.45%)
  • Nuclear receptor (23.68%)

What were the highlights of his more recent work (between 2017-2021)?

  • Internal medicine (36.09%)
  • Endocrinology (30.45%)
  • Cell biology (11.65%)

In recent papers he was focusing on the following fields of study:

David D. Moore mostly deals with Internal medicine, Endocrinology, Cell biology, Cancer research and Constitutive androstane receptor. His Internal medicine study frequently draws connections between related disciplines such as Gastroenterology. His research on Endocrinology often connects related topics like Nuclear receptor.

His Cell biology research incorporates elements of Autophagy, Small intestine, Epigenomics, Gene and Enterohepatic circulation. His Cancer research research includes themes of Cancer, Protein kinase B, Inflammatory bowel disease and MAPK/ERK pathway. As a part of the same scientific family, David D. Moore mostly works in the field of Constitutive androstane receptor, focusing on Cytokine and, on occasion, Cytotoxic T cell.

Between 2017 and 2021, his most popular works were:

  • miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity (35 citations)
  • MAPK4 overexpression promotes tumor progression via noncanonical activation of AKT/mTOR signaling (23 citations)
  • Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice (19 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His main research concerns Cell biology, Internal medicine, Cancer research, Autophagy and Heart failure. David D. Moore has included themes like White Adipocytes, Inflammasome, Liver cell, Gene product and Cell fate determination in his Cell biology study. His Endocrinology research extends to the thematically linked field of Internal medicine.

His studies deal with areas such as Proinflammatory cytokine, Inflammation and microRNA as well as Endocrinology. His work on Hepatocellular carcinoma as part of general Cancer research study is frequently connected to TGF alpha, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Autophagy research incorporates themes from Body weight and Brown adipose tissue, Brown Adipocytes.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Redundant Pathways for Negative Feedback Regulation of Bile Acid Production

Li Wang;Yoon-Kwang Lee;Donnie Bundman;Yunqing Han.
Developmental Cell (2002)

493 Citations

The Xenobiotic Compound 1,4-Bis(2-(3,5-Dichloropyridyloxy))Benzene Is an Agonist Ligand for the Nuclear Receptor CAR

Iphigenia Tzameli;Pavlos Pissios;Erin G. Schuetz;David D. Moore.
Molecular and Cellular Biology (2000)

456 Citations

Preparation and Analysis of DNA

David D. Moore;Dennis Dowhan.
Current Protocols in Molecular Biology (2002)

422 Citations

Induction of bilirubin clearance by the constitutive androstane receptor (CAR)

Wendong Huang;Jun Zhang;Steven S. Chua;Mohammed Qatanani.
Proceedings of the National Academy of Sciences of the United States of America (2003)

414 Citations

Spontaneous Development of Liver Tumors in the Absence of the Bile Acid Receptor Farnesoid X Receptor

Fan Yang;Xiongfei Huang;Xiongfei Huang;Tangsheng Yi;Yun Yen.
Cancer Research (2007)

405 Citations

Modulation of Acetaminophen-Induced Hepatotoxicity by the Xenobiotic Receptor CAR

Jun Zhang;Wendong Huang;Steven S. Chua;Ping Wei.
Science (2002)

353 Citations

The Farnesoid X-activated Receptor Mediates Bile Acid Activation of Phospholipid Transfer Protein Gene Expression *

Nancy L. Urizar;Dennis H. Dowhan;David D. Moore.
Journal of Biological Chemistry (2000)

338 Citations

Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor.

Wendong Huang;Jun Zhang;Michele Washington;Jun Liu;Jun Liu.
Molecular Endocrinology (2005)

315 Citations

Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor.

R J Koenig;R L Warne;G A Brent;J W Harney.
Proceedings of the National Academy of Sciences of the United States of America (1988)

308 Citations

Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response

P Wei;J Zhang;D H Dowhan;Y Han.
Pharmacogenomics Journal (2002)

307 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing David D. Moore

Wen Xie

Wen Xie

University of Pittsburgh

Publications: 72

Frank J. Gonzalez

Frank J. Gonzalez

National Institutes of Health

Publications: 62

Li Wang

Li Wang

Yale University

Publications: 61

Michael Trauner

Michael Trauner

Medical University of Vienna

Publications: 53

Curtis D. Klaassen

Curtis D. Klaassen

University of Kansas

Publications: 53

Bart Staels

Bart Staels

University of Lille

Publications: 52

Masahiko Negishi

Masahiko Negishi

National Institutes of Health

Publications: 50

Jan-Åke Gustafsson

Jan-Åke Gustafsson

University of Houston

Publications: 43

Ronald M. Evans

Ronald M. Evans

Salk Institute for Biological Studies

Publications: 42

Kristina Schoonjans

Kristina Schoonjans

École Polytechnique Fédérale de Lausanne

Publications: 41

William W. Chin

William W. Chin

Harvard Medical School

Publications: 40

Stefano Fiorucci

Stefano Fiorucci

University of Perugia

Publications: 39

Mitchell A. Lazar

Mitchell A. Lazar

University of Pennsylvania

Publications: 38

David J. Mangelsdorf

David J. Mangelsdorf

The University of Texas Southwestern Medical Center

Publications: 38

Steven A. Kliewer

Steven A. Kliewer

The University of Texas Southwestern Medical Center

Publications: 34

John W. Harney

John W. Harney

Brigham and Women's Hospital

Publications: 33

Trending Scientists

Mike Sharples

Mike Sharples

The Open University

David S. Johnson

David S. Johnson

AT&T (United States)

Ikuro Abe

Ikuro Abe

University of Tokyo

Alex G. Harrison

Alex G. Harrison

University of Toronto

Nikhil Gupta

Nikhil Gupta

New York University

Andrew R. Leitch

Andrew R. Leitch

Queen Mary University of London

Charles Mitter

Charles Mitter

University of Maryland, College Park

Matthias Wilmanns

Matthias Wilmanns

European Bioinformatics Institute

Eva Maria Mandelkow

Eva Maria Mandelkow

Center of Advanced European Studies and Research

Karen Helen Wiltshire

Karen Helen Wiltshire

Alfred Wegener Institute for Polar and Marine Research

David W. J. Thompson

David W. J. Thompson

University of East Anglia

Karl M. Newell

Karl M. Newell

University of Georgia

Peter Schmid-Grendelmeier

Peter Schmid-Grendelmeier

University of Zurich

Paul Kennedy

Paul Kennedy

Stoke Mandeville Hospital

Christine Mannhalter

Christine Mannhalter

Medical University of Vienna

Carle Paul

Carle Paul

Federal University of Toulouse Midi-Pyrénées

Something went wrong. Please try again later.