World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
27617
World Ranking
2338
National Ranking
1248

Masahiko Negishi publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Masahiko Negishi sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 324 publications — 82nd percentile

82% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Masahiko Negishi D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Masahiko Negishi sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 91 D-Index — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Masahiko Negishi is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, with additional significant contributions to Medicine. Within these broader areas, their work spans several subfields including Molecular Biology, Genetics, Endocrinology, Diabetes and Metabolism, Pharmacology, and Oncology.

The research topics covered by Negishi include:

  • Estrogen and related hormone effects
  • Hormonal Regulation and Hypertension
  • Pharmacogenetics and Drug Metabolism
  • Receptor Mechanisms and Signaling
  • Protein Kinase Regulation and GTPase Signaling
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Chemokine receptors and signaling

Negishi has contributed to multiple publications, particularly in well-known venues such as UNC Libraries, Biochemical Pharmacology, Biochemical and Biophysical Research Communications, Journal of Biological Chemistry, and Methods in Molecular Biology.

Recent publications by or closely associated with Negishi include:

  • Nuclear receptor phosphorylation in xenobiotic signal transduction, 2020, Journal of Biological Chemistry
  • Estrogen Sulfotransferase (SULT1E1): Its Molecular Regulation, Polymorphisms, and Clinical Perspectives, 2021, Journal of Personalized Medicine
  • Human constitutive androstane receptor represses liver cancer development and hepatoma cell proliferation by inhibiting erythropoietin signaling, 2022, Journal of Biological Chemistry
  • Estrogen receptor α phosphorylated at Ser216 confers inflammatory function to mouse microglia, 2020, Cell Communication and Signaling
  • Nuclear receptor CAR-ERα signaling regulates the estrogen sulfotransferase gene in the liver, 2020, Scientific Reports

The scientist frequently collaborates with other researchers including Kosuke Yokobori, Tatsuya Sueyoshi, Rick Moore, MyeongJin Yi, and Sawako Shindo.

Best Publications

  • THE NUCLEAR ORPHAN RECEPTOR CAR-RETINOID X RECEPTOR HETERODIMER ACTIVATES THE PHENOBARBITAL-RESPONSIVE ENHANCER MODULE OF THE CYP2B GENE

    Paavo Honkakoski;Igor Zelko;Tatsuya Sueyoshi;Masahiko Negishi

  • The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene.

    Tatsuya Sueyoshi;Takeshi Kawamoto;Igor Zelko;Paavo Honkakoski

  • Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene

    Takeshi Kawamoto;Tatsuya Sueyoshi;Igor Zelko;Rick Moore

  • Regulation of cytochrome P450 (CYP) genes by nuclear receptors

    Paavo Honkakoski;Masahiko Negishi

  • CAR and PXR: the xenobiotic-sensing receptors.

    Yoav E. Timsit;Masahiko Negishi

  • Diverse Roles of the Nuclear Orphan Receptor CAR in Regulating Hepatic Genes in Response to Phenobarbital

    Akiko Ueda;Hisham K. Hamadeh;Heather K. Webb;Yukio Yamamoto

  • Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue.

    Raija L. P. Lindberg;Masahiko Negishi

  • The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

    Junko Sugatani;Hiroyuki Kojima;Akiko Ueda;Satoru Kakizaki

  • Structure and function of sulfotransferases.

    Masahiko Negishi;Lee G. Pedersen;Lee G. Pedersen;Evgeniy Petrotchenko;Sergei Shevtsov

  • Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes

    Susumu Kodama;Chika Koike;Masahiko Negishi;Yukio Yamamoto

  • The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice.

    Yukio Yamamoto;Rick Moore;Thomas L. Goldsworthy;Masahiko Negishi

  • Genetic Mechanisms Controlling the Induction of Polysubstrate Monooxygenase (P-450) Activities

    D. W. Nebert;H. J. Eisen;M. Negishi;M. A. Lang

  • Developmental exposure to diethylstilbestrol elicits demethylation of estrogen-responsive lactoferrin gene in mouse uterus

    Shuanfang Li;Kimberly A. Washburn;Rick Moore;Tomohide Uno

  • Crystal structure of estrogen sulphotransferase

    Yoshimitsu Kakuta;Lee G. Pedersen;Charles W. Carter;Masahiko Negishi

  • Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity.

    Grace L. Guo;Gilles Lambert;Masahiko Negishi;Jerrold M. Ward

  • Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers

    Stephanie R. Faucette;Tong Cun Zhang;Rick Moore;Tatsuya Sueyoshi

  • Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia.

    Junko Sugatani;Kasumi Yamakawa;Kouich Yoshinari;Takashi Machida

  • Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor.

    Yuping Chen;Stephen S. Ferguson;Masahiko Negishi;Joyce A. Goldstein

  • Heparan/chondroitin sulfate biosynthesis. Structure and mechanism of human glucuronyltransferase I.

    Lars C. Pedersen;Kazunori Tsuchida;Hiroshi Kitagawa;Kazuyuki Sugahara

  • Synthesis and insertion of cytochrome P-450 into endoplasmic reticulum membranes.

    Shoshana Bar-Nun;Gert Kreibich;Milton Adesnik;Lon Alterman

Frequent Co-Authors

Lars C. Pedersen
Lars C. Pedersen National Institutes of Health
Lee G. Pedersen
Lee G. Pedersen University of North Carolina at Chapel Hill
Daniel W. Nebert
Daniel W. Nebert University of Cincinnati
Paavo Honkakoski
Paavo Honkakoski University of Eastern Finland
Joyce A. Goldstein
Joyce A. Goldstein National Institutes of Health
Robert H. Tukey
Robert H. Tukey University of California, San Diego
Edward L. LeCluyse
Edward L. LeCluyse Research Triangle Park Foundation
Yuan-Tsong Chen
Yuan-Tsong Chen Harbor–UCLA Medical Center
Takeshi Kawamoto
Takeshi Kawamoto Hiroshima University
Lalith Perera
Lalith Perera National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Masahiko Negishi

Trending Scientists

Recently Published Articles