Robert H. Tukey

Overview

Best Publications

• Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease

  Robert H. Tukey;Christian P. Strassburg

  2167
  Citations

• Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor

  Wen Xie;Mei-Fei Yeuh;Anna Radominska-Pandya;Simrat P. S. Saini

  429
  Citations

• Metabolism of 2-Acetylaminofluorene and Benzo(a)pyrene and Activation of Food-derived Heterocyclic Amine Mutagens by Human Cytochromes P-450

  Michael E. McManus;Wendy M. Burgess;Maurice E. Veronese;Anthony Huggett

  419
  Citations

• Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2.

  W Tassaneeyakul;D J Birkett;M E Veronese;M E McManus

  416
  Citations

• Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue : identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue

  Christian P. Strassburg;Karl Oldhafer;Michael P. Manns;Robert H. Tukey

  397
  Citations

• Expression of the UDP-glucuronosyltransferase 1A Locus in Human Colon: IDENTIFICATION AND CHARACTERIZATION OF THE NOVEL EXTRAHEPATIC UGT1A8 *

  Christian P. Strassburg;Michael P. Manns;Robert H. Tukey

  390
  Citations

• Developmental aspects of human hepatic drug glucuronidation in young children and adults

  C P Strassburg;A Strassburg;S Kneip;A Barut

  371
  Citations

• Polymorphic Gene Regulation and Interindividual Variation of UDP-glucuronosyltransferase Activity in Human Small Intestine

  Christian P. Strassburg;Susanne Kneip;Juliane Topp;Petra Obermayer-Straub

  351
  Citations

• Genetic Multiplicity of the Human UDP-Glucuronosyltransferases and Regulation in the Gastrointestinal Tract

  Robert H. Tukey;Christian P. Strassburg

  337
  Citations

• Triclosan: A Widespread Environmental Toxicant with Many Biological Effects

  Mei-Fei Yueh;Robert H. Tukey

  320
  Citations

• Expression of modified human cytochrome P450 1A2 in Escherichia coli: stabilization, purification, spectral characterization, and catalytic activities of the enzyme.

  Punam Sandhu;Zuyu Guo;T. Baba;M. V. Martin

  267
  Citations

• Caffeine metabolism by human hepatic cytochromes p450: Contributions of 1A2, 2E1 and 3A isoforms

  Wichittra Tassaneeyakul;Donald J. Birkett;Michael E. McManus;Wongwiwat Tassaneeyakul

  260
  Citations

• The commonly used antimicrobial additive triclosan is a liver tumor promoter

  Mei-Fei Yueh;Koji Taniguchi;Shujuan Chen;Ronald M. Evans

  258
  Citations

• UDP-glucuronosyltransferase activity in human liver and colon

  Christian P. Strassburg;Nghia Nguyen;Michael P. Manns;Robert H. Tukey

  252
  Citations

• The human CYP1A2 gene and induction by 3-methylcholanthrene. A region of DNA that supports AH-receptor binding and promoter-specific induction.

  L C Quattrochi;T Vu;R H Tukey

  248
  Citations

• The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA

  Robert H. Tukey;Rita R. Hannah;Masahiko Negishi;Daniel W. Nebert

  246
  Citations

• Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1

  Mei-Fei Yueh;Yue-Hua Huang;Anita Hiller;Shujuan Chen

  241
  Citations

• Protein kinase C modulates regulation of the CYP1A1 gene by the aryl hydrocarbon receptor.

  Yue-Hwa Chen;Robert H. Tukey

  223
  Citations

• Structural gene products of the Ah locus. Transcriptional regulation of cytochrome P1-450 and P3-450 mRNA levels by 3-methylcholanthrene.

  F J Gonzalez;R H Tukey;D W Nebert

  222
  Citations

• Response of Human CYP1-Luciferase Plasmids to 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Polycyclic Aromatic Hydrocarbons

  H Postlind;T P Vu;R H Tukey;L C Quattrochi

  218
  Citations