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Chantal Guillemette

Chantal Guillemette

D-Index & Metrics

Molecular Biology

D-Index
59
Citations
11532
World Ranking
2025
National Ranking
62

Overview

Chantal Guillemette is affiliated with Université Laval in Canada and has an active research profile focused on medical and biochemical sciences. Their work spans various fields including Medicine and Biochemistry, Genetics, and Molecular Biology. Key subfields of interest are Pulmonary and Respiratory Medicine, Genetics, Endocrinology, Diabetes and Metabolism, Molecular Biology, and Cancer Research.

The research topics often explored by Guillemette cover multiple areas related to cancer and hormonal studies. Notable topics include Prostate Cancer Treatment and Research, Hormonal and Reproductive Studies, Estrogen and Related Hormone Effects, Pharmacogenetics and Drug Metabolism, Chronic Lymphocytic Leukemia Research, Cancer, Hypoxia, and Metabolism, as well as Prostate Cancer Diagnosis and Treatment.

Some of the recent publications by Guillemette provide insight into their research themes:

  • Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression, 2020, British Journal of Cancer
  • A quantitative analysis of total and free 11-oxygenated androgens and its application to human serum and plasma specimens using liquid-chromatography tandem mass spectrometry, 2021, Journal of Chromatography A
  • Endogenous estradiol and inflammation biomarkers: potential interacting mechanisms of obesity-related disease, 2020, Cancer Causes & Control
  • KLF5 and NFYA factors as novel regulators of prostate cancer cell metabolism, 2021, Endocrine Related Cancer
  • UGT2B17 modifies drug response in chronic lymphocytic leukaemia, 2020, British Journal of Cancer

Guillemette frequently collaborates with several researchers, including:

  • Patrick Caron
  • Éric Lévesque
  • Louis Lacombe
  • Michèle Rouleau
  • David Simonyan

The scientist's work is often published in venues such as:

  • British Journal of Cancer
  • The Journal of Urology
  • UNC Libraries
  • Frontiers in Endocrinology
  • Journal of Chromatography A

Chantal Guillemette's research encompasses both experimental and clinical aspects of cancer and hormonal metabolism with a significant focus on pharmacogenetics, drug metabolism, and cancer progression mechanisms. The interdisciplinary approach is supported by contributions to journals across oncology, endocrinology, and biochemistry, reflecting the breadth of their expertise. This profile indicates a sustained research output with broad implications particularly in understanding cancer biology and therapeutic responses.

Best Publications

  • Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily.

    Peter I Mackenzie;Karl Walter Bock;Brian Burchell;Chantal Guillemette

  • Pharmacogenomics of human UDP-glucuronosyltransferase enzymes.

    C Guillemette

  • Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

    Jean-François Gagné;Valerie Montminy;Patrick Belanger;Kim Journault

  • Glucuronidation and the UDP-glucuronosyltransferases in health and disease

    Peter G. Wells;Peter I. Mackenzie;Jayanta Roy Chowdhury;Chantal Guillemette

  • Genetic Polymorphisms in Uridine Diphospho-Glucuronosyltransferase 1A1 and Association with Breast Cancer among African Americans

    Chantal Guillemette;Robert C. Millikan;Beth Newman;David E. Housman

  • Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium.

    Johanie Lépine;Olivier Bernard;Marie Plante;Bernard Têtu

  • Novel Functional Polymorphisms in the UGT1A7 and UGT1A9 Glucuronidating Enzymes in Caucasian and African-American Subjects and Their Impact on the Metabolism of 7-Ethyl-10-hydroxycamptothecin and Flavopiridol Anticancer Drugs

    Lyne Villeneuve;Hugo Girard;Louis-Charles Fortier;Jean-Francois Gagné

  • Direct haplotyping of kilobase-size DNA using carbon nanotube probes.

    Adam T. Woolley;Chantal Guillemette;Chin Li Cheung;David E. Housman

  • The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants.

    Olivier Bernard;Chantal Guillemette

  • Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs) : S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9

    Michael H. Court;Su X. Duan;Chantal Guillemette;Kim Journault

  • Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene.

    Chantal Guillemette;Joseph K. Ritter;Diana J. Auyeung;Fay K. Kessler

  • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing

    Roseann S. Gammal;Michael H. Court;Cyrine E. Haidar;Otito Frances Iwuchukwu

  • Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.

    Hugo Girard;Michael H Court;Olivier Bernard;Louis-Charles Fortier

  • The Impact of UGT1A8, UGT1A9, and UGT2B7 Genetic Polymorphisms on the Pharmacokinetic Profile of Mycophenolic Acid After a Single Oral Dose in Healthy Volunteers

    Lévesque E;Delage R;Benoit-Biancamano Mo;Caron P

  • Tobacco Carcinogen-Detoxifying Enzyme UGT1A7 and Its Association With Orolaryngeal Cancer Risk

    Zhong Zheng;Jong Y. Park;Chantal Guillemette;Stimson P. Schantz

  • Pharmacogenomics of Human Uridine Diphospho-Glucuronosyltransferases and Clinical Implications

    Chantal Guillemette;Éric Lévesque;Michèle Rouleau

  • Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes

    Shinichiro Ogawa;James Surapisitchat;Carl Virtanen;Mina Ogawa

  • Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine.

    Anne Sophie Bélanger;Patrick Caron;Mario Harvey;Peter A. Zimmerman

  • UGT genomic diversity: beyond gene duplication

    Chantal Guillemette;Eric Lévesque;Mario Harvey;Judith Bellemare

  • The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor alpha and gamma target gene.

    Olivier Barbier;Lyne Villeneuve;Virginie Bocher;Coralie Fontaine

Frequent Co-Authors

Alain Bélanger
Alain Bélanger Université Laval
Yves Fradet
Yves Fradet Université Laval
David J. Greenblatt
David J. Greenblatt Tufts University
Olivier Barbier
Olivier Barbier Université Laval
Ruth M. Pfeiffer
Ruth M. Pfeiffer National Institutes of Health
Laurence Klotz
Laurence Klotz University of Toronto
Christian C. Abnet
Christian C. Abnet National Institutes of Health
Immaculata De Vivo
Immaculata De Vivo Harvard University
Lisa L. von Moltke
Lisa L. von Moltke Tufts University
Fred Saad
Fred Saad University of Montreal

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