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Biology and Biochemistry

D-Index
82
Citations
20251
World Ranking
3760
National Ranking
1860

Overview

Philip Lazarus is affiliated with Washington State University Spokane in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a notable focus on Molecular Biology, Pharmacology, Genetics, Cancer Research, and Otorhinolaryngology.

The scientist's work covers several main topics including Epigenetics and DNA Methylation, Cannabis and Cannabinoid Research, RNA modifications and cancer, Pharmacogenetics and Drug Metabolism, Head and Neck Cancer Studies, Genetic Associations and Epidemiology, as well as Glutathione Transferases and Polymorphisms.

Philip Lazarus has contributed to multiple recent scientific papers in respected journals. These include:

  • "Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization" (2020, International Journal of Cancer)
  • "Alcohol drinking and head and neck cancer risk: the joint effect of intensity and duration" (2020, British Journal of Cancer)
  • "Cannabinoid Metabolites as Inhibitors of Major Hepatic CYP450 Enzymes, with Implications for Cannabis-Drug Interactions" (2021, Drug Metabolism and Disposition)
  • "Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer" (2022, Nature Genetics)
  • "Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model" (2021, Cancer Research)

The scientist frequently collaborates with a consistent group of co-authors, including:

  • Paul Brennan
  • David C. Christiani
  • Geoffrey Liu
  • Rayjean J. Hung
  • Susanne M. Arnold

Philip Lazarus has published extensively in several well-known venues, which include:

  • UNC Libraries
  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • The FASEB Journal
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium.

    Mia Hashibe;Paul Brennan;Shu Chun Chuang;Stefania Boccia

  • Metabolic gene polymorphism frequencies in control populations.

    S. Garte;L. Gaspari;A.K. Alexandrie;C. Ambrosone

  • Alcohol Drinking in Never Users of Tobacco, Cigarette Smoking in Never Drinkers, and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium

    Mia Hashibe;Paul Brennan;Simone Benhamou;Xavier Castellsague

  • Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

    James D McKay;Rayjean J Hung;Younghun Han;Xuchen Zong

  • Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

    Robert Carreras-Torres;Mattias Johansson;Philip C. Haycock;Kaitlin H. Wade

  • Cessation of alcohol drinking, tobacco smoking and the reversal of head and neck cancer risk

    Manuela Marron;Manuela Marron;Paolo Boffetta;Zuo Feng Zhang;David Zaridze

  • Cigarette, Cigar, and Pipe Smoking and the Risk of Head and Neck Cancers: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium

    Annah Wyss;Mia Hashibe;Shu Chun Chuang;Yuan Chin Amy Lee

  • A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium

    James D. McKay;Therese Truong;Valerie Gaborieau;Amelie Chabrier

  • Adult height and head and neck cancer: A pooled analysis within the INHANCE Consortium

    E. Leoncini;W. Ricciardi;G. Cadoni;D. Arzani

  • Meta- and pooled analyses of GSTM1, GSTT1, GSTP1, and CYP1A1 genotypes and risk of head and neck cancer

    Mia Hashibe;Paul Brennan;Richard C. Strange;Rajani Bhisey

  • Total Exposure and Exposure Rate Effects for Alcohol and Smoking and Risk of Head and Neck Cancer: A Pooled Analysis of Case-Control Studies

    Jay H. Lubin;Mark Purdue;Karl Kelsey;Zuo Feng Zhang

  • Previous Lung Diseases and Lung Cancer Risk: A Pooled Analysis From the International Lung Cancer Consortium

    Darren R. Brenner;Paolo Boffetta;Eric J. Duell;Heike Bickeböller

  • The human OGG1 DNA repair enzyme and its association with orolaryngeal cancer risk.

    Abul Elahi;Zhong Zheng;Jong Park;Kathy Eyring

  • Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium

    Michele L. Coté;Mei Liu;Stefano Bonassi;Monica Neri

  • Genetic differences detected by comparative genomic hybridization in head and neck squamous cell carcinomas from different tumor sites: construction of oncogenetic trees for tumor progression.

    Qiang Huang;Guo Pei Yu;Steven A. McCormick;Juan Mo

  • Replication of Lung Cancer Susceptibility Loci at Chromosomes 15q25, 5p15, and 6p21: A Pooled Analysis From the International Lung Cancer Consortium

    Therese Truong;Rayjean J. Hung;Christopher I. Amos;Xifeng Wu

  • Diet and the risk of head and neck cancer: A pooled analysis in the INHANCE consortium

    Shu Chun Chuang;Shu Chun Chuang;Mazda Jenab;Julia E. Heck;Cristina Bosetti

  • Tobacco Carcinogen-Detoxifying Enzyme UGT1A7 and Its Association With Orolaryngeal Cancer Risk

    Zhong Zheng;Jong Y. Park;Chantal Guillemette;Stimson P. Schantz

  • CYP1A1 and GSTM1 polymorphisms and oral cancer risk.

    Jong Y. Park;Joshua E. Muscat;Qing Ren;Stimson P. Schantz

  • Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium

    Li Rita Zhang;Hal Morgenstern;Sander Greenland;Shen Chih Chang

Frequent Co-Authors

Joshua E. Muscat
Joshua E. Muscat Pennsylvania State University
Gang Chen
Gang Chen Guangxi Medical University
Rayjean J. Hung
Rayjean J. Hung Lunenfeld-Tanenbaum Research Institute
Paul Brennan
Paul Brennan International Agency For Research On Cancer
Stig E. Bojesen
Stig E. Bojesen University of Copenhagen
Zuo-Feng Zhang
Zuo-Feng Zhang University of California, Los Angeles
Paolo Boffetta
Paolo Boffetta Stony Brook Medicine
David C. Christiani
David C. Christiani Harvard University
Angela Risch
Angela Risch University of Salzburg
Chu Chen
Chu Chen Fred Hutchinson Cancer Research Center

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