World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
80
Citations
25128
World Ranking
17047
National Ranking
715

Overview

Rayjean J. Hung is affiliated with the Lunenfeld-Tanenbaum Research Institute in Canada, contributing extensively to the fields of Biochemistry, Genetics, and Molecular Biology as well as Medicine. Their research spans significant topics within molecular biology, genetics, pulmonary and respiratory medicine, and oncology.

The scientist's work includes a focus on genetic associations, epidemiology, epigenetics and DNA methylation, and RNA modifications related to cancer. Their research further extends into cancer-related molecular mechanisms, as well as lung cancer treatments, diagnosis, and head and neck cancer studies.

Rayjean J. Hung's recent notable publications include:

  • "Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis," 2022, BMC Medicine
  • "Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization," 2020, International Journal of Cancer
  • "A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer," 2020, Nature Communications
  • "Tobacco Smoking and Risk of Second Primary Lung Cancer," 2021, Journal of Thoracic Oncology
  • "Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers," 2020, Nature Communications

Their frequent collaborators include:

  • Christopher I. Amos
  • Geoffrey Liu
  • Paul Brennan
  • David C. Christiani
  • James McKay

Rayjean J. Hung publishes often in these venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Thoracic Oncology
  • Cancer Research
  • Nature Communications
  • JNCI Journal of the National Cancer Institute

The breadth of research contributions covers over 200 publications focusing on molecular biology and medicine, with a substantial number dedicated to cancer research and respiratory medicine. Their work frequently addresses the genetic and molecular underpinnings of cancer and respiratory diseases utilizing Mendelian randomization and related epidemiological methods.

Best Publications

  • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

    Rayjean J. Hung;James D. Mckay;Valerie Gaborieau;Paolo Boffetta

  • Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

    James D McKay;Rayjean J Hung;Younghun Han;Xuchen Zong

  • Sensitive tumour detection and classification using plasma cell-free DNA methylomes

    Shu Yi Shen;Rajat Singhania;Gordon Fehringer;Ankur Chakravarthy

  • Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

    Robert Carreras-Torres;Mattias Johansson;Philip C. Haycock;Kaitlin H. Wade

  • Lung cancer susceptibility locus at 5p15.33

    James D McKay;Rayjean J Hung;Rayjean J Hung;Valerie Gaborieau;Paolo Boffetta

  • Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors

    Michael L. Nickerson;Erich Jaeger;Yangu Shi;Jeffrey A. Durocher

  • Genetic Polymorphisms in the Base Excision Repair Pathway and Cancer Risk: A HuGE Review

    Rayjean J. Hung;Janet Hall;Paul Brennan;Paolo Boffetta

  • A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma.

    Maria Teresa Landi;Nilanjan Chatterjee;Kai Yu;Lynn R. Goldin

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

    Yufei Wang;James D McKay;Thorunn Rafnar;Zhaoming Wang

  • Previous Lung Diseases and Lung Cancer Risk: A Systematic Review and Meta-Analysis

    Darren R. Brenner;Darren R. Brenner;John R. McLaughlin;John R. McLaughlin;John R. McLaughlin;Rayjean J. Hung;Rayjean J. Hung

  • The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.

    Christopher I. Amos;Joe Dennis;Zhaoming Wang;Jinyoung Byun

  • TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke : distinct patterns in never, former, and current smokers

    Florence Le Calvez;Anush Mukeria;Jay D. Hunt;Olaf Kelm

  • CYP1A1 and GSTM1 genetic polymorphisms and lung cancer risk in Caucasian non-smokers: a pooled analysis.

    Rayjean J. Hung;Paolo Boffetta;Jürgen Brockmöller;Dorota Butkiewicz

  • Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors

    Thomas Vaissière;Rayjean J. Hung;David Zaridze;Anush Moukeria

  • A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium

    James D. McKay;Therese Truong;Valerie Gaborieau;Amelie Chabrier

  • Genetic polymorphisms of MPO, COMT, MnSOD, NQO1, interactions with environmental exposures and bladder cancer risk

    Rayjean J. Hung;Paolo Boffetta;Paul Brennan;Christian Malaveille

  • Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

    Erica J Childs;Evelina Mocci;Daniele Campa;Daniele Campa;Paige M Bracci

  • Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

    Maria N. Timofeeva;Rayjean J. Hung;Thorunn Rafnar;David C. Christiani

  • GST, NAT, SULT1A1, CYP1B1 genetic polymorphisms, interactions with environmental exposures and bladder cancer risk in a high-risk population

    Rayjean J. Hung;Paolo Boffetta;Paul Brennan;Christian Malaveille

Frequent Co-Authors

Paul Brennan
Paul Brennan International Agency For Research On Cancer
Christopher I. Amos
Christopher I. Amos Baylor College of Medicine
Geoffrey Liu
Geoffrey Liu Princess Margaret Cancer Centre
David C. Christiani
David C. Christiani Harvard University
Angela Risch
Angela Risch University of Salzburg
Paolo Boffetta
Paolo Boffetta Stony Brook Medicine
John K. Field
John K. Field University of Liverpool
Maria Teresa Landi
Maria Teresa Landi National Institutes of Health
Stig E. Bojesen
Stig E. Bojesen University of Copenhagen
James McKay
James McKay International Agency For Research On Cancer

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