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Biology and Biochemistry

D-Index
83
Citations
33620
World Ranking
3438
National Ranking
82

Overview

James McKay is affiliated with the International Agency For Research On Cancer in France. Their research spans fields including Biochemistry, Genetics and Molecular Biology, and Medicine, with notable subfields in Molecular Biology, Genetics, Cancer Research, Pulmonary and Respiratory Medicine, and Pathology and Forensic Medicine.

McKay's scientific contributions focus on several key topics: Genetic Associations and Epidemiology, Epigenetics and DNA Methylation, RNA modifications and cancer, Cancer Genomics and Diagnostics, Cancer-related molecular mechanisms research, Chronic Lymphocytic Leukemia Research, and Genetic factors in colorectal cancer.

Their recent publications include:

  • Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence (2021) in Nature Genetics
  • Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers (2020) in Nature Communications
  • Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer (2022) in Nature Genetics
  • Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model (2021) in Cancer Research
  • Urinary TERT promoter mutations are detectable up to 10 years prior to clinical diagnosis of bladder cancer: Evidence from the Golestan Cohort Study (2020) in EBioMedicine

Frequent co-authors collaborating with McKay include Paul Brennan, Rayjean J. Hung, Christopher I. Amos, Mattias Johansson, and Geoffrey Liu.

McKay's work is published in several prominent venues. The most common publication venues for their research are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Cancer Research
  • International Journal of Cancer
  • Nature Communications

Best Publications

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

    Rayjean J. Hung;James D. Mckay;Valerie Gaborieau;Paolo Boffetta

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • Genome-wide meta-analyses identify multiple loci associated with smoking behavior

    Helena Furberg;Yunjung Kim;Jennifer Dackor;Eric Boerwinkle

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

    James D McKay;Rayjean J Hung;Younghun Han;Xuchen Zong

  • Prediction of acute myeloid leukaemia risk in healthy individuals

    Sagi Abelson;Grace Collord;Grace Collord;Stanley W.K. Ng;Omer Weissbrod

  • Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

    Robert Carreras-Torres;Mattias Johansson;Philip C. Haycock;Kaitlin H. Wade

  • Lung cancer susceptibility locus at 5p15.33

    James D McKay;Rayjean J Hung;Rayjean J Hung;Valerie Gaborieau;Paolo Boffetta

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma.

    Maria Teresa Landi;Nilanjan Chatterjee;Kai Yu;Lynn R. Goldin

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • Heterogeneity of Breast Cancer Associations with Five Susceptibility Loci by Clinical and Pathological Characteristics

    Montserrat Garcia-Closas;Per Hall;Heli Nevanlinna;Karen Pooley

  • Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

    Yufei Wang;James D McKay;Thorunn Rafnar;Zhaoming Wang

  • Genome-wide association study reveals two new risk loci for bipolar disorder

    Thomas W. Mühleisen;Thomas W. Mühleisen;Markus Leber;Markus Leber;Thomas G. Schulze;Jana Strohmaier

  • The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers.

    Christopher I. Amos;Joe Dennis;Zhaoming Wang;Jinyoung Byun

  • Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

    Julie George;Vonn Walter;Vonn Walter;Martin Peifer;Ludmil B. Alexandrov

Frequent Co-Authors

Paul Brennan
Paul Brennan International Agency For Research On Cancer
Graham G. Giles
Graham G. Giles University of Melbourne
Rayjean J. Hung
Rayjean J. Hung Lunenfeld-Tanenbaum Research Institute
Jolanta Lissowska
Jolanta Lissowska Maria Sklodowska-Curie National Research Institute of Oncology
Stephen J. Chanock
Stephen J. Chanock National Institutes of Health
Christopher I. Amos
Christopher I. Amos Baylor College of Medicine
Lenka Foretova
Lenka Foretova Masaryk University
Paolo Boffetta
Paolo Boffetta Stony Brook Medicine
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Stig E. Bojesen
Stig E. Bojesen University of Copenhagen

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