Atsushi Matsuzawa

Overview

Best Publications

• ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

  Hideki Nishitoh;Atsushi Matsuzawa;Kei Tobiume;Kaoru Saegusa

  1623
  Citations

• ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

  Kei Tobiume;Atsushi Matsuzawa;Takumi Takahashi;Hideki Nishitoh

  1440
  Citations

• ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

  Atsushi Matsuzawa;Kaoru Saegusa;Takuya Noguchi;Chiharu Sadamitsu

  775
  Citations

• Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

  Sivakumar Vallabhapurapu;Atsushi Matsuzawa;Wei Zhou Zhang;Ping Hui Tseng

  744
  Citations

• ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

  Hideki Nishitoh;Hisae Kadowaki;Atsushi Nagai;Takeshi Maruyama

  621
  Citations

• Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

  Toshiharu Sakurai;Guobin He;Atsushi Matsuzawa;Guann Yi Yu

  576
  Citations

• Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling.

  Atsushi Matsuzawa;Hidenori Ichijo

  573
  Citations

• Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation

  H. Kadowaki;H. Kadowaki;H. Nishitoh;H. Nishitoh;Fumihiko Urano;C. Sadamitsu

  526
  Citations

• Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

  Ping Hui Tseng;Atsushi Matsuzawa;Atsushi Matsuzawa;Weizhou Zhang;Takashi Mino

  477
  Citations

• The ASK1-MAP Kinase Cascades in Mammalian Stress Response

  Jun Matsukawa;Atsushi Matsuzawa;Kohsuke Takeda;Hidenori Ichijo

  425
  Citations

• Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

  Takiko Hatai;Atsushi Matsuzawa;Seiji Inoshita;Yoshiyuki Mochida

  423
  Citations

• Stress-responsive protein kinases in redox-regulated apoptosis signaling.

  Atsushi Matsuzawa;Hidenori Ichijo

  348
  Citations

• Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1.

  Go Fujino;Takuya Noguchi;Atsushi Matsuzawa;Shota Yamauchi

  321
  Citations

• Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice.

  Atsushi Matsuzawa;Hideki Nishitoh;Kei Tobiume;Kohsuke Takeda

  314
  Citations

• Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death.

  Takuya Noguchi;Kohsuke Takeda;Atsushi Matsuzawa;Kaoru Saegusa

  289
  Citations

• Roles of MAPKKK ASK1 in stress-induced cell death.

  Kohsuke Takeda;Kohsuke Takeda;Atsushi Matsuzawa;Hideki Nishitoh;Hideki Nishitoh;Hidenori Ichijo;Hidenori Ichijo

  286
  Citations

• Essential Cytoplasmic Translocation of a Cytokine Receptor–Assembled Signaling Complex

  Atsushi Matsuzawa;Ping Hui Tseng;Sivakumar Vallabhapurapu;Jun Li Luo

  268
  Citations

• Apoptosis signal-regulating kinase 1 plays a pivotal role in angiotensin II-induced cardiac hypertrophy and remodeling

  Yasuhiro Izumiya;Shokei Kim;Yasukatsu Izumi;Kaoru Yoshida

  267
  Citations

• Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

  Osamu Yamaguchi;Tetsuya Watanabe;Kazuhiko Nishida;Kazunori Kashiwase

  231
  Citations

• Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1.

  Atsushi Matsuzawa;Hidenori Ichijo

  225
  Citations