Hiroyuki Arai

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Japan Leader Award
• 2025 - Research.com Biology and Biochemistry in Japan Leader Award
• 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Best Publications

• Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment.

  B. Winblad;K. Palmer;Miia Kivipelto;V. Jelic

  5983
  Citations

• Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium

  I. G. McKeith;I. G. McKeith;D. W. Dickson;J. Lowe;M. Emre

  5905
  Citations

• Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production.

  Makiko Umezu-Goto;Yasuhiro Kishi;Akitsu Taira;Kotaro Hama

  1061
  Citations

• Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease'

  Peter Davies;Judith Resnick;Burton Resnick;Sid Gilman

  840
  Citations

• LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing.

  Xiaoqin Ye;Kotaro Hama;James J. A. Contos;Brigitte Anliker

  694
  Citations

• Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist

  Thomas M. McIntyre;Aaron V. Pontsler;Adriana R. Silva;Andy St. Hilaire

  690
  Citations

• Activation of STING requires palmitoylation at the Golgi

  Kojiro Mukai;Hiroyasu Konno;Tatsuya Akiba;Takefumi Uemura

  661
  Citations

• Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation

  Kosei Eguchi;Ichiro Manabe;Yumiko Oishi-Tanaka;Mitsuru Ohsugi

  577
  Citations

• Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor

  Mitsuharu Hattori;Hideki Adachi;Masafumi Tsujimoto;Hiroyuki Arai

  572
  Citations

• Green tea consumption and cognitive function: a cross-sectional study from the Tsurugaya Project

  Shinichi Kuriyama;Atsushi Hozawa;Kaori Ohmori;Taichi Shimazu

  559
  Citations

• Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid

  Masayuki Tanaka;Shinichi Okudaira;Yasuhiro Kishi;Ryunosuke Ohkawa

  540
  Citations

• The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

  Masayuki Morita;Keiji Kuba;Akihiko Ichikawa;Mizuho Nakayama

  532
  Citations

• Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways

  Junken Aoki;Akitsu Taira;Yasukazu Takanezawa;Yasuhiro Kishi

  530
  Citations

• Longitudinal study of cerebrospinal fluid levels of tau, Aβ1–40, and Aβ1–42(43) in Alzheimer's disease: A study in Japan

  M. Kanai;E. Matsubara;K. Isoe;K. Urakami

  486
  Citations

• Cerebrospinal Fluid Tau and β-Amyloid: How Well Do These Biomarkers Reflect Autopsy-Confirmed Dementia Diagnoses?

  Christopher M. Clark;Sharon Xie;Jesse Chittams;Douglas Ewbank

  470
  Citations

• TGFα shedding assay: an accurate and versatile method for detecting GPCR activation

  Asuka Inoue;Jun Ishiguro;Hajime Kitamura;Naoaki Arima

  456
  Citations

• The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

  Niklas Mattsson;Ulf Andreasson;Staffan Persson;Hiroyuki Arai

  452
  Citations

• A randomized, observer-blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms and activities of daily living in dementia patients.

  Koh Iwasaki;Takuma Satoh-Nakagawa;Masahiro Maruyama;Yasutake Monma

  429
  Citations

• Tau in cerebrospinal fluid: A potential diagnostic marker in Alzheimer's disease

  Hiroyuki Arai;Masanori Terajima;Masakazu Miura;Susumu Higuchi

  405
  Citations

• Activation of STING requires palmitoylation at the Golgi

  Kojiro Mukai;Tomohiko Taguchi;Hiroyuki Arai

  1
  Citations