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Biology and Biochemistry

D-Index
67
Citations
29793
World Ranking
8046
National Ranking
3648

Overview

Jason T. Huse is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research encompasses the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a primary focus on Molecular Biology, Genetics, Cancer Research, Pulmonary and Respiratory Medicine, and Neurology.

Their scientific work specializes in several main topics including:

  • Glioma Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Single-cell and spatial transcriptomics
  • MicroRNA in disease regulation
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Immune cells in cancer
  • Chromatin Remodeling and Cancer

Among their recent published papers are:

  • "Glioma progression is shaped by genetic evolution and microenvironment interactions" (2022, Cell)
  • "YTHDF3 Induces the Translation of m6A-Enriched Gene Transcripts to Promote Breast Cancer Brain Metastasis" (2020, Cancer Cell)
  • "Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance" (2020, Science Translational Medicine)
  • "Classification of adult-type diffuse gliomas: Impact of the World Health Organization 2021 update" (2022, Brain Pathology)
  • "OncoTree: A Cancer Classification System for Precision Oncology" (2021, JCO Clinical Cancer Informatics)

Jason T. Huse has frequently collaborated with several researchers, including:

  • Frederick F. Lang
  • Prit Benny Malgulwar
  • Sharvari Dharmaiah
  • Roel G.W. Verhaak
  • Frederick S. Varn

Their work has been published predominantly in the following venues:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Neuro-Oncology Advances

Best Publications

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • CSF-1R inhibition alters macrophage polarization and blocks glioma progression

    Stephanie M Pyonteck;Leila Akkari;Alberto J Schuhmacher;Robert L Bowman

  • IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

    Sevin Turcan;Daniel Rohle;Daniel Rohle;Anuj Goenka;Logan A. Walsh

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

    Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot

  • Glioma Groups Based on 1p/19q, IDH, and TERT Promoter Mutations in Tumors

    Jeanette E Eckel-Passow;Daniel H Lachance;Annette M. Molinaro;Kyle M. Walsh

  • PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.

    Anne Marie Bleau;Dolores Hambardzumyan;Tatsuya Ozawa;Elena I. Fomchenko

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

    Jason T. Huse;Eric C. Holland

  • Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis

    Manuel Valiente;Anna C. Obenauf;Xin Jin;Qing Chen

  • The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

    Jason T. Huse;Cameron Brennan;Dolores Hambardzumyan;Boyoung Wee

  • Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

    Nicholas J. Szerlip;Alicia Pedraza;Debyani Chakravarty;Mohammad Azim

  • The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas

    Daniela F. Quail;Robert L. Bowman;Leila Akkari;Leila Akkari;Leila Akkari;Marsha L. Quick

  • Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

    Alexander Pietras;Amanda M. Katz;Elin J. Ekström;Boyoung Wee

  • Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

    Nicholas Butowski;Howard Colman;John F. De Groot;Antonio M. Omuro

  • The Mutational Landscape of Adenoid Cystic Carcinoma

    Allen S Ho;Kasthuri Kannan;David M Roy;Luc G T Morris

  • Benefit From Procarbazine, Lomustine, and Vincristine in Oligodendroglial Tumors Is Associated With Mutation of IDH

    J. Gregory Cairncross;Meihua Wang;Robert B. Jenkins;Edward G. Shaw

  • Longitudinal molecular trajectories of diffuse glioma in adults

    Floris P. Barthel;Kevin C. Johnson;Frederick S. Varn;Anzhela D. Moskalik

  • Most Human Non-GCIMP Glioblastoma Subtypes Evolve from a Common Proneural-like Precursor Glioma

    Tatsuya Ozawa;Markus Riester;Yu Kang Cheng;Jason T. Huse

  • Stereotactic Radiosurgery for Melanoma Brain Metastases in Patients Receiving Ipilimumab: Safety Profile and Efficacy of Combined Treatment

    Ana P. Kiess;Ana P. Kiess;Jedd D. Wolchok;Christopher A. Barker;Michael A. Postow

Frequent Co-Authors

Cameron Brennan
Cameron Brennan Memorial Sloan Kettering Cancer Center
Eric C. Holland
Eric C. Holland Fred Hutchinson Cancer Research Center
Timothy A. Chan
Timothy A. Chan Cleveland Clinic
Gregory N. Fuller
Gregory N. Fuller The University of Texas MD Anderson Cancer Center
Marc K. Rosenblum
Marc K. Rosenblum Memorial Sloan Kettering Cancer Center
Keith L. Ligon
Keith L. Ligon Harvard University
Ingo K. Mellinghoff
Ingo K. Mellinghoff Memorial Sloan Kettering Cancer Center
Adriana Heguy
Adriana Heguy New York University
Nikolaus Schultz
Nikolaus Schultz Memorial Sloan Kettering Cancer Center
Lisa M. DeAngelis
Lisa M. DeAngelis Memorial Sloan Kettering Cancer Center

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