What is he best known for?
The fields of study he is best known for:
Eric C. Holland mainly investigates Cancer research, Glioma, Pathology, Protein kinase B and Signal transduction.
His biological study spans a wide range of topics, including Endocrinology, Internal medicine, Stem cell, Nestin and PI3K/AKT/mTOR pathway.
Eric C. Holland conducts interdisciplinary study in the fields of Glioma and Context through his research.
The concepts of his Pathology study are interwoven with issues in Oligodendroglial Tumor, Genetically engineered, In vivo and Oligoastrocytoma.
His work in Protein kinase B addresses subjects such as Regulation of gene expression, which are connected to disciplines such as microRNA, Tensin, Transcriptome, Transcriptional regulation and Anti-apoptotic Ras signalling cascade.
His Signal transduction research includes elements of Cell cycle and PDGFB.
His most cited work include:
- A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival (2094 citations)
- CSF-1R inhibition alters macrophage polarization and blocks glioma progression (1073 citations)
- Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice (765 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cancer research, Glioma, Pathology, Cell biology and Glioblastoma.
Eric C. Holland has researched Cancer research in several fields, including Protein kinase B, Carcinogenesis, Immunology, Platelet-derived growth factor receptor and Stem cell.
His PI3K/AKT/mTOR pathway research extends to the thematically linked field of Protein kinase B.
While the research belongs to areas of Glioma, Eric C. Holland spends his time largely on the problem of Internal medicine, intersecting his research to questions surrounding Endocrinology.
Eric C. Holland has researched Pathology in several fields, including Magnetic resonance imaging and Oligodendroglioma.
His Cell biology study incorporates themes from Cell cycle, Cell culture and Gene expression.
He most often published in these fields:
- Cancer research (57.77%)
- Glioma (45.45%)
- Pathology (18.18%)
What were the highlights of his more recent work (between 2018-2021)?
- Cancer research (57.77%)
- Glioma (45.45%)
- Immune system (5.57%)
In recent papers he was focusing on the following fields of study:
Eric C. Holland spends much of his time researching Cancer research, Glioma, Immune system, Glioblastoma and Carcinogenesis.
His Cancer research research incorporates elements of Abscopal effect, Immunotherapy and Immunity.
His Glioma research integrates issues from Patterns of failure, Confidence interval, Treatment failure, Radiosurgery and Salvage therapy.
Eric C. Holland interconnects Interferon, Macrophage and Platelet-derived growth factor receptor in the investigation of issues within Immune system.
In his research on the topic of Glioblastoma, Internal medicine and Oncology is strongly related with Relevance.
His work carried out in the field of Carcinogenesis brings together such families of science as DNA damage, Hippo signaling pathway, Cell growth, Mutant and Cell biology.
Between 2018 and 2021, his most popular works were:
- Challenges to curing primary brain tumours (159 citations)
- Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers (84 citations)
- Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers (84 citations)
In his most recent research, the most cited papers focused on:
His primary areas of investigation include Cancer research, Glioma, Immunotherapy, Immune system and Isocitrate dehydrogenase.
His Cancer research research includes elements of Cell, Abscopal effect, Transcription factor, Immunity and Mesenchymal stem cell.
Brain tumor is closely connected to T cell in his research, which is encompassed under the umbrella topic of Cell.
Eric C. Holland has included themes like Lesion, Platelet-derived growth factor, Platelet-derived growth factor receptor and Epidermal growth factor receptor in his Abscopal effect study.
His research integrates issues of Cancer cell, Inflammation, Chemokine, Microglia and Innate immune system in his study of Glioma.
His Mutant study also includes fields such as
- Copy number analysis together with Internal medicine and Oncology,
- Epigenome, which have a strong connection to Carcinogenesis.
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