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Medicine

D-Index
110
Citations
51221
World Ranking
5500
National Ranking
2963

Research.com Recognitions

  • 2009 - Member of the National Academy of Medicine (NAM)

Overview

Eric C. Holland is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to Molecular Biology, Genetics, Immunology, Cancer Research, and Oncology.

Eric C. Holland has contributed extensively to the study of gliomas and related brain tumors. Main topics of their work include:

  • Glioma Diagnosis and Treatment
  • Meningioma and schwannoma management
  • Hippo pathway signaling and YAP/TAZ
  • Immune cells in cancer
  • RNA Research and Splicing
  • Neurofibromatosis and Schwannoma Cases
  • Cancer Genomics and Diagnostics

Frequent publication venues where Holland's work appears include:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Scientific Reports
  • Genes & Development
  • Acta Neuropathologica Communications

Their research collaborations involve repeated work with certain co-authors, notably:

  • Frank Szulzewsky
  • Patrick J. Cimino
  • Sonali Arora
  • Nicholas Nuechterlein
  • Felix Sahm

Several of their notable recent papers include:

  • "cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas," 2020, Acta Neuropathologica
  • "Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression," 2020, Nature Communications
  • "Wnt-mediated endothelial transformation into mesenchymal stem cell-like cells induces chemoresistance in glioblastoma," 2020, Science Translational Medicine
  • "YAP1 and its fusion proteins in cancer initiation, progression and therapeutic resistance," 2021, Developmental Biology
  • "Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain," 2021, Nature Cancer

Eric C. Holland was recognized as a Member of the National Academy of Medicine in 2009.

Best Publications

  • A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival

    Michel Lacroix;Dima Abi-Said;Daryl R. Fourney;Ziya L. Gokaslan

  • CSF-1R inhibition alters macrophage polarization and blocks glioma progression

    Stephanie M Pyonteck;Leila Akkari;Alberto J Schuhmacher;Robert L Bowman

  • A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle

    Moritz F Kircher;Adam de la Zerda;Jesse V Jokerst;Cristina L Zavaleta

  • Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

    Eric C. Holland;Joseph Celestino;Chengkai Dai;Laura Schaefer

  • Glioblastoma multiforme: The terminator

    Eric C. Holland

  • PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.

    Anne Marie Bleau;Dolores Hambardzumyan;Tatsuya Ozawa;Elena I. Fomchenko

  • Differential exoprotease activities confer tumor-specific serum peptidome patterns

    Josep Villanueva;David R. Shaffer;John Philip;Carlos A. Chaparro

  • Identification of a multipotent astrocytic stem cell in the immature and adult mouse brain

    Eric D. Laywell;Pasko Rakic;Valery G. Kukekov;Eric C. Holland

  • Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

    Jason T. Huse;Eric C. Holland

  • Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO

    Victoria E. Clark;E. Zeynep Erson-Omay;Akdes Serin;Jun Yin

  • PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

    Chengkai Dai;Joseph C. Celestino;Yoshifumi Okada;David N. Louis

  • cIMPACT-NOW Update 3: Recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV”

    Daniel J. Brat;Kenneth Aldape;Howard Colman;Eric C. Holland

  • HIV-1 tat trans-activation requires the loop sequence within tar

    Sandy Feng;Eric C. Holland

  • The brain tumor microenvironment.

    Nikki A. Charles;Eric C. Holland;Richard Gilbertson;Rainer Glass

  • Challenges to curing primary brain tumours

    Kenneth Aldape;Kevin M Brindle;Louis Chesler;Rajesh Chopra

  • The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

    Jason T. Huse;Cameron Brennan;Dolores Hambardzumyan;Boyoung Wee

  • A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

    Eric C. Holland;Wendy P. Hively;Ronald A. DePinho;Harold E. Varmus

  • Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations.

    Cameron Brennan;Hiroyuki Momota;Dolores Hambardzumyan;Tatsuya Ozawa

  • Gliomagenesis: genetic alterations and mouse models

    Eric C. Holland

  • A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle

    Adam de la Zerda;Moritz F. Kircher;Moritz F. Kircher;Jesse V. Jokerst;Cristina L. Zavaleta

Frequent Co-Authors

Jason T. Huse
Jason T. Huse The University of Texas MD Anderson Cancer Center
Cameron Brennan
Cameron Brennan Memorial Sloan Kettering Cancer Center
Ingo K. Mellinghoff
Ingo K. Mellinghoff Memorial Sloan Kettering Cancer Center
Lisa M. DeAngelis
Lisa M. DeAngelis Memorial Sloan Kettering Cancer Center
Franziska Michor
Franziska Michor Harvard University
Gregory N. Fuller
Gregory N. Fuller The University of Texas MD Anderson Cancer Center
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Brian D. Ross
Brian D. Ross University of Michigan–Ann Arbor
Michael Weller
Michael Weller University of Zurich
Andrey Korshunov
Andrey Korshunov German Cancer Research Center

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