The scientist’s investigation covers issues in Cancer research, Glioma, Bioinformatics, Mutation and Pathology. His biological study spans a wide range of topics, including Carcinogenesis, Cancer, Immunology, microRNA and PI3K/AKT/mTOR pathway. His work in the fields of Glioma, such as Astrocytoma, overlaps with other areas such as Macrophage colony-stimulating factor.
The study incorporates disciplines such as Immunohistochemistry, Gene expression profiling, Genomics, Exome and Disease in addition to Bioinformatics. His studies deal with areas such as AKT1, Histone H3, Epigenetics and Somatic cell as well as Mutation. Keith L. Ligon focuses mostly in the field of Pathology, narrowing it down to topics relating to Oligodendrocyte and, in certain cases, Embryonic stem cell and Gene expression.
His primary areas of study are Cancer research, Glioma, Internal medicine, Pathology and Oncology. The Cancer research study combines topics in areas such as Cell and Carcinogenesis, Cancer, Gene, Mutation. His Glioma research is multidisciplinary, incorporating elements of Phenotype, IDH1 and Bioinformatics.
Keith L. Ligon has included themes like Surgery and Glioblastoma in his Internal medicine study. His research integrates issues of Exome sequencing, Magnetic resonance imaging, Oligodendroglioma and PTEN in his study of Pathology. His Oncology research includes themes of Bevacizumab and Clinical endpoint.
Cancer research, Oncology, Internal medicine, Glioma and Glioblastoma are his primary areas of study. His studies in Cancer research integrate themes in fields like Mutation, Cell, Cancer and Gene knockdown. His Cell research incorporates themes from Cellular differentiation, RNA, Cancer stem cell, Transcriptome and Ependymoma.
His research investigates the connection between Cancer and topics such as Temozolomide that intersect with issues in Precision medicine and DNA mismatch repair. His work deals with themes such as O-6-methylguanine-DNA methyltransferase, Phases of clinical research, Lymphocyte and Immunotherapy, which intersect with Oncology. He interconnects Mutant, PTEN and Pathology in the investigation of issues within Glioma.
Keith L. Ligon focuses on Cancer research, Oncology, Internal medicine, Computational biology and RNA. His Cancer research research focuses on Glioma in particular. The concepts of his Glioma study are interwoven with issues in Gene expression, PTEN, Single-cell analysis, Receptor and Buparlisib.
His Oncology research includes elements of Immune checkpoint, Corticosteroid, Myeloid and Lymphocyte. His work on Dexamethasone, Blockade, Immunotherapy and Biopsy as part of general Internal medicine study is frequently linked to Context, bridging the gap between disciplines. As a member of one scientific family, Keith L. Ligon mostly works in the field of Computational biology, focusing on Cellular differentiation and, on occasion, Cell.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Malignant astrocytic glioma: genetics, biology, and paths to treatment.
Frank B. Furnari;Tim Fenton;Robert M. Bachoo;Akitake Mukasa.
Genes & Development (2007)
Coactivation of Receptor Tyrosine Kinases Affects the Response of Tumor Cells to Targeted Therapies
Jayne M. Stommel;Alec C. Kimmelman;Haoqiang Ying;Roustem Nabioullin.
p16INK4a induces an age-dependent decline in islet regenerative potential.
Janakiraman Krishnamurthy;Matthew R. Ramsey;Keith L. Ligon;Chad Torrice.
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
Cyril Neftel;Julie Laffy;Mariella G. Filbin;Toshiro Hara.
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.
Robert M Bachoo;Elizabeth A Maher;Keith L Ligon;Norman E Sharpless.
Cancer Cell (2002)
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
Hongwu Zheng;Haoqiang Ying;Haiyan Yan;Alec C. Kimmelman.
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
Derin B. Keskin;Annabelle J. Anandappa;Jing Sun;Itay Tirosh.
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
Priscilla K. Brastianos;Scott L. Carter;Scott L. Carter;Sandro Santagata;Sandro Santagata;Daniel P. Cahill.
Cancer Discovery (2015)
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.
Yoon Jae Cho;Aviad Tsherniak;Pablo Tamayo;Sandro Santagata.
Journal of Clinical Oncology (2011)
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
David T W Jones;Barbara Hutter;Natalie Jäger;Andrey Korshunov;Andrey Korshunov.
Nature Genetics (2013)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: