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Biology and Biochemistry

D-Index
69
Citations
35330
World Ranking
7219
National Ranking
3311

Overview

Azra H. Ligon is affiliated with Brigham and Women's Hospital in the United States. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Genetics, Neurology, Molecular Biology, Epidemiology, and Cancer Research.

Their main topics of research include:

  • Glioma Diagnosis and Treatment
  • Meningioma and schwannoma management
  • Neuroblastoma Research and Treatments
  • Cancer Genomics and Diagnostics
  • Radiomics and Machine Learning in Medical Imaging
  • Neurofibromatosis and Schwannoma Cases
  • Brain Metastases and Treatment

Azra H. Ligon has contributed to multiple scientific papers, including notable recent publications such as:

  • Mechanisms and therapeutic implications of hypermutation in gliomas (2020), published in Nature
  • A Novel SS18-SSX Fusion-specific Antibody for the Diagnosis of Synovial Sarcoma (2020), published in The American Journal of Surgical Pathology
  • A molecularly integrated grade for meningioma (2021), published in Neuro-Oncology
  • A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study (2021), published in Neuro-Oncology
  • Molecular and clinicopathologic features of gliomas harboring NTRK fusions (2020), published in Acta Neuropathologica Communications

Frequent co-authors working alongside Azra H. Ligon include:

  • Keith L. Ligon
  • Rameen Beroukhim
  • Wenya Linda Bi
  • Sandro Santagata
  • Patrick Y. Wen

Their work is regularly published in several key venues such as:

  • Neuro-Oncology
  • The American Journal of Surgical Pathology
  • Clinical Cancer Research
  • Modern Pathology
  • WFNOS 2022 Abstract Book

Best Publications

  • The landscape of somatic copy-number alteration across human cancers

    Rameen Beroukhim;Craig H. Mermel;Craig H. Mermel;Dale Porter;Guo Wei

  • Identification of a candidate tumour suppressor gene, MMAC1 , at chromosome 10q23.3 that is mutated in multiple advanced cancers

    P. A. Steck;M. A. Pershouse;S. A. Jasser;W. K. A. Yung

  • PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma

    Stephen M. Ansell;Alexander M. Lesokhin;Alexander M. Lesokhin;Ivan Borrello;Ahmad Halwani

  • Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

    Jason W. Locasale;Alexandra R. Grassian;Tamar Melman;Costas A. Lyssiotis

  • Recurrent BRAF mutations in Langerhans cell histiocytosis

    Gayane Badalian-Very;Gayane Badalian-Very;Jo-Anne Vergilio;Jo-Anne Vergilio;Barbara A. Degar;Barbara A. Degar;Laura E. MacConaill

  • Nivolumab in patients with relapsed or refractory hematologic malignancy: Preliminary results of a phase ib study

    Alexander M. Lesokhin;Alexander M. Lesokhin;Stephen M. Ansell;Philippe Armand;Emma C. Scott

  • Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial

    Anas Younes;Armando Santoro;Margaret Shipp;Pier Luigi Zinzani

  • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.

    Yoon Jae Cho;Aviad Tsherniak;Pablo Tamayo;Sandro Santagata

  • CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

    Ron Firestein;Adam Bass;So Young Kim;Ian Frederick Dunn

  • PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome

    Margaretha G.M. Roemer;Ranjana H. Advani;Azra H. Ligon;Yasodha Natkunam

  • Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

    Ulrich Schüller;Vivi M. Heine;Vivi M. Heine;Junhao Mao;Alvin T. Kho

  • Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma

    Derek Y. Chiang;Augusto Villanueva;Yujin Hoshida;Yujin Hoshida;Judit Peix

  • Mechanisms and therapeutic implications of hypermutation in gliomas.

    Mehdi Touat;Mehdi Touat;Mehdi Touat;Yvonne Y. Li;Yvonne Y. Li;Adam N. Boynton;Adam N. Boynton;Liam F. Spurr;Liam F. Spurr

  • Targetable genetic features of primary testicular and primary central nervous system lymphomas

    Bjoern Chapuy;Margaretha G. M. Roemer;Margaretha G. M. Roemer;Chip Stewart;Yuxiang Tan

  • Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

    Adam M. Fontebasso;Simon Papillon-Cavanagh;Jeremy Schwartzentruber;Hamid Nikbakht

  • Clinical Activity of mTOR Inhibition With Sirolimus in Malignant Perivascular Epithelioid Cell Tumors: Targeting the Pathogenic Activation of mTORC1 in Tumors

    Andrew J. Wagner;Izabela Malinowska-Kolodziej;Jeffrey A. Morgan;Wei Qin

  • Validation of OncoPanel: A Targeted Next-Generation Sequencing Assay for the Detection of Somatic Variants in Cancer.

    Elizabeth P. Garcia;Alissa Minkovsky;Yonghui Jia;Matthew D. Ducar

  • Institutional implementation of clinical tumor profiling on an unselected cancer population

    Lynette M. Sholl;Khanh Do;Priyanka Shivdasani;Ethan Cerami

  • Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial.

    Jason Fangusaro;Arzu Onar-Thomas;Tina Young Poussaint;Shengjie Wu

  • Integration of cytogenetic landmarks into the draft sequence of the human genome

    V. G. Cheung;N. Nowak;W. Jang;I. R. Kirsch

Frequent Co-Authors

Keith L. Ligon
Keith L. Ligon Harvard University
Rameen Beroukhim
Rameen Beroukhim Harvard University
Sandro Santagata
Sandro Santagata Brigham and Women's Hospital
Cynthia C. Morton
Cynthia C. Morton Brigham and Women's Hospital
Patrick Y. Wen
Patrick Y. Wen Harvard University
Scott J. Rodig
Scott J. Rodig Harvard University
Matthew Meyerson
Matthew Meyerson Harvard University
Neal I. Lindeman
Neal I. Lindeman Brigham and Women's Hospital
Massimo Loda
Massimo Loda Cornell University
Margaret A. Shipp
Margaret A. Shipp Harvard University

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