World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
132
Citations
81287
World Ranking
2283
National Ranking
1290

Overview

Scott J. Rodig is affiliated with Harvard University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a specific focus on oncology and related biomedical disciplines.

The scientist has a substantial publication record in oncology, with notable subfields of study including Oncology, Molecular Biology, Immunology, Pulmonary and Respiratory Medicine, and Cancer Research.

Main topics of their work reflect these interests and include:

  • Cancer Immunotherapy and Biomarkers
  • Cancer Genomics and Diagnostics
  • CAR-T cell therapy research
  • Single-cell and spatial transcriptomics
  • Lung Cancer Treatments and Mutations
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses

Scott J. Rodig's frequent co-authors are Kathleen L. Pfaff, Mark M. Awad, Joao V. Alessi, Jason L. Weirather, and Biagio Ricciuti, reflecting collaborative work within these research domains.

Their recent papers include the following:

  • "Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma," 2021, Nature Medicine
  • "Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems," 2021, Science
  • "Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels," 2022, JAMA Oncology
  • "Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer," 2020, Nature Communications
  • "Axicabtagene Ciloleucel in the Non-Trial Setting: Outcomes and Correlates of Response, Resistance, and Toxicity," 2020, Journal of Clinical Oncology

The scientist has published extensively in multiple venues, with the most frequent being:

  • Journal of Clinical Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Blood
  • Cold Spring Harbor Protocols

Scott J. Rodig's research contributions focus on the molecular and immunological underpinnings of cancer, including therapeutic approaches such as CAR-T cell therapy and immune checkpoint blockade. Their work integrates clinical insights with molecular genomics and spatial transcriptomics techniques.

Best Publications

  • PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's Lymphoma

    Stephen M. Ansell;Alexander M. Lesokhin;Alexander M. Lesokhin;Ivan Borrello;Ahmad Halwani

  • An immunogenic personal neoantigen vaccine for patients with melanoma

    Patrick A. Ott;Zhuting Hu;Derin B. Keskin;Derin B. Keskin;Sachet A. Shukla;Sachet A. Shukla

  • Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK

    Alice T. Shaw;Beow Y. Yeap;Mari Mino-Kenudson;Subba R. Digumarthy

  • Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

    Marco A Meraz;Marco A Meraz;J.Michael White;Kathleen C.F Sheehan;Erika A Bach

  • Comprehensive analyses of tumor immunity: implications for cancer immunotherapy

    Bo Li;Eric Severson;Eric Severson;Jean Christophe Pignon;Haoquan Zhao

  • Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade.

    Brian C. Miller;Debattama R. Sen;Debattama R. Sen;Rose Al Abosy;Rose Al Abosy;Kevin Bi;Kevin Bi

  • Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

    Bjoern Chapuy;Chip Stewart;Andrew J Dunford;Jaegil Kim

  • Adaptive immunity maintains occult cancer in an equilibrium state

    Catherine M. Koebel;William Vermi;William Vermi;Jeremy B. Swann;Jeremy B. Swann;Nadeen Zerafa

  • Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.

    Shohei Koyama;Esra A. Akbay;Yvonne Y. Li;Grit S. Herter-Sprie

  • Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

    Michael R. Green;Stefano Monti;Scott J. Rodig;Przemyslaw Juszczynski

  • MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

    Steven P. Treon;Lian Xu;Guang Yang;Yangsheng Zhou

  • Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

    Derin B. Keskin;Annabelle J. Anandappa;Jing Sun;Itay Tirosh

  • Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors

    Esra A. Akbay;Esra A. Akbay;Shohei Koyama;Julian Carretero;Abigail Altabef;Abigail Altabef

  • Nivolumab in patients with relapsed or refractory hematologic malignancy: Preliminary results of a phase ib study

    Alexander M. Lesokhin;Alexander M. Lesokhin;Stephen M. Ansell;Philippe Armand;Emma C. Scott

  • Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses

    Scott J Rodig;Marco A Meraz;J.Michael White;Pat A Lampe

  • Nivolumab for classical Hodgkin's lymphoma after failure of both autologous stem-cell transplantation and brentuximab vedotin: a multicentre, multicohort, single-arm phase 2 trial

    Anas Younes;Armando Santoro;Margaret Shipp;Pier Luigi Zinzani

  • Ibrutinib in Previously Treated Waldenström’s Macroglobulinemia

    Steven P. Treon;Christina K. Tripsas;Kirsten Meid;Diane Warren

  • Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor.

    James E. Butrynski;David R. D’Adamo;Jason L. Hornick;Paola Dal Cin

  • PD-L1 EXPRESSION IS CHARACTERISTIC OF A SUBSET OF AGGRESSIVE B-CELL LYMPHOMAS AND VIRUS-ASSOCIATED MALIGNANCIES

    Benjamin J. Chen;Bjoern Chapuy;Jing Ouyang;Heather H. Sun

  • Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells

    Kian Peng Koh;Akiko Yabuuchi;Sridhar Rao;Yun Huang

Frequent Co-Authors

Margaret A. Shipp
Margaret A. Shipp Harvard University
Donna Neuberg
Donna Neuberg Harvard University
Philippe Armand
Philippe Armand Harvard University
Gordon J. Freeman
Gordon J. Freeman Harvard University
F. Stephen Hodi
F. Stephen Hodi Harvard University
Jeffery L. Kutok
Jeffery L. Kutok Epizyme (United States)
Gad Getz
Gad Getz Broad Institute
Geoffrey I. Shapiro
Geoffrey I. Shapiro Harvard University
Andrew L. Kung
Andrew L. Kung Memorial Sloan Kettering Cancer Center
Catherine J. Wu
Catherine J. Wu Harvard University

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