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Immunology

D-Index
92
Citations
57305
World Ranking
987
National Ranking
538

Medicine

D-Index
92
Citations
57324
World Ranking
11065
National Ranking
5693

Overview

Catherine J. Wu is affiliated with Harvard University in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a focus on oncology, immunology, molecular biology, genetics, and hematology.

The researcher has contributed extensively to topics including CAR-T cell therapy research, cancer immunotherapy and biomarkers, chronic lymphocytic leukemia research, cancer genomics and diagnostics, immune cell function and interaction, single-cell and spatial transcriptomics, and immunotherapy and immune responses.

Some of the recent papers by Catherine J. Wu include:

  • Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma, 2020, Nature Medicine
  • A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors, 2020, Nature Medicine
  • Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals downregulation of retained introns, 2020, Nature Communications
  • Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma, 2021, Nature
  • Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma, 2021, Nature Medicine

They frequently collaborate with researchers including Donna Neuberg, Kenneth J. Livak, Robert J. Soiffer, Jerome Ritz, and Gad Getz, reflecting a broad network within their specialized fields.

The venues that commonly publish their work are:

  • Blood
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood Advances
  • Journal of Clinical Oncology

Best Publications

  • Mutational heterogeneity in cancer and the search for new cancer-associated genes

    Michael S. Lawrence;Petar Stojanov;Petar Stojanov;Paz Polak;Paz Polak;Paz Polak;Gregory V. Kryukov;Gregory V. Kryukov;Gregory V. Kryukov

  • Molecular and genetic properties of tumors associated with local immune cytolytic activity.

    Michael S. Rooney;Sachet A. Shukla;Catherine J. Wu;Gad Getz

  • Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

    Nicholas McGranahan;Nicholas McGranahan;Andrew J. S. Furness;Rachel Rosenthal;Sofie Ramskov

  • Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

    Eliezer M. Van Allen;Eliezer M. Van Allen;Diana Miao;Diana Miao;Bastian Schilling;Sachet A. Shukla;Sachet A. Shukla

  • An immunogenic personal neoantigen vaccine for patients with melanoma

    Patrick A. Ott;Zhuting Hu;Derin B. Keskin;Derin B. Keskin;Sachet A. Shukla;Sachet A. Shukla

  • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

    A. Gordon Robertson;Jaegil Kim;Hikmat Al-Ahmadie;Joaquim Bellmunt

  • Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

    Dan A. Landau;Scott L. Carter;Petar Stojanov;Petar Stojanov;Aaron McKenna

  • Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

    Derin B. Keskin;Annabelle J. Anandappa;Jing Sun;Itay Tirosh

  • SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

    Lili Wang;Michael S. Lawrence;Youzhong Wan;Petar Stojanov

  • Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

    Joshua D Campbell;Anton Alexandrov;Jaegil Kim;Jeremiah Wala

  • Towards personalized, tumour-specific, therapeutic vaccines for cancer

    Zhuting Hu;Patrick A. Ott;Patrick A. Ott;Catherine J. Wu

  • Mutations driving CLL and their evolution in progression and relapse.

    Dan A. Landau;Eugen Tausch;Amaro N. Taylor-Weiner;Chip Stewart

  • Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

    Marios Giannakis;Marios Giannakis;Marios Giannakis;Xinmeng Jasmine Mu;Xinmeng Jasmine Mu;Xinmeng Jasmine Mu;Sachet A. Shukla;Sachet A. Shukla;Zhi Rong Qian

  • Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

    David A. Braun;David A. Braun;Yue Hou;Ziad Bakouny;Miriam Ficial;Miriam Ficial

  • A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

    Michal Slyper;Caroline B. M. Porter;Orr Ashenberg;Julia Waldman

  • Comprehensive analysis of cancer-associated somatic mutations in class I HLA genes

    Sachet A Shukla;Sachet A Shukla;Sachet A Shukla;Michael S Rooney;Michael S Rooney;Mohini Rajasagi;Grace Tiao

  • Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer.

    Kyle C. Strickland;Brooke E Howitt;Sachet A Shukla;Scott J. Rodig

  • Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1

    Brooke Elizabeth Howitt;Sachet Shukla;Lynette Marie Sholl;Lauren Lee Ritterhouse

  • Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction.

    Jennifer G. Abelin;Derin B. Keskin;Siranush Sarkizova;Christina R. Hartigan

  • Chronic lymphocytic leukaemia.

    Thomas J. Kipps;Freda K. Stevenson;Catherine J. Wu;Carlo M. Croce

  • Ipilimumab for Patients with Relapse after Allogeneic Transplantation

    Matthew S. Davids;Haesook T. Kim;Pavan Bachireddy;Caitlin Costello

Frequent Co-Authors

Donna Neuberg
Donna Neuberg Harvard University
Jerome Ritz
Jerome Ritz Harvard University
Gad Getz
Gad Getz Broad Institute
Sachet A. Shukla
Sachet A. Shukla The University of Texas MD Anderson Cancer Center
Nir Hacohen
Nir Hacohen Harvard University
Robert J. Soiffer
Robert J. Soiffer Harvard University
Jennifer R. Brown
Jennifer R. Brown Harvard University
Edwin P. Alyea
Edwin P. Alyea Harvard University
Eric S. Lander
Eric S. Lander Broad Institute
Joseph H. Antin
Joseph H. Antin Dana-Farber Cancer Institute

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