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Akira Shimizu

Akira Shimizu

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
16772
World Ranking
7403
National Ranking
500

Overview

Akira Shimizu is affiliated with Kyoto University in Japan and has an extensive publication record primarily focused on medicine, with particular expertise in nephrology. Their research spans several subfields, including surgery, pulmonary and respiratory medicine, molecular biology, and immunology.

The scientist's work addresses a variety of topics, notably in renal diseases and glomerulopathies, chronic kidney disease and diabetes, vasculitis and related conditions, amyloidosis diagnosis and treatment outcomes, pediatric urology and nephrology studies, organ transplantation techniques and outcomes, and quantum many-body systems.

Frequent collaborators contributing to their research include Akiko Mii, Mika Terasaki, Kazuhiro Takeuchi, Takashi Yokoo, and Shinobu Kunugi.

Shimizu's research has been published extensively in the following venues:

  • Clinical and Experimental Nephrology
  • Journal of the American Society of Nephrology
  • CEN Case Reports
  • Kidney International Reports
  • Internal Medicine

Recent notable papers include:

  • Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice (2020) - Journal of the American Society of Nephrology
  • Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties (2020) - Nature Communications
  • Adjuvant S-1 plus endocrine therapy for oestrogen receptor-positive, HER2-negative, primary breast cancer: a multicentre, open-label, randomised, controlled, phase 3 trial (2020) - The Lancet Oncology
  • Consistent survival in consecutive cases of life-supporting porcine kidney xenotransplantation using 10GE source pigs (2024) - Nature Communications
  • Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig-to-baboon xenotransplantation (2021) - Xenotransplantation

Best Publications

  • Safety and Antitumor Activity of Anti–PD-1 Antibody, Nivolumab, in Patients With Platinum-Resistant Ovarian Cancer

    Junzo Hamanishi;Masaki Mandai;Takafumi Ikeda;Manabu Minami

  • Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience.

    Kenji Kuwaki;Yau Lin Tseng;Frank J.M.F. Dor;Akira Shimizu

  • Molecular cloning of cDNA encoding human interleukin-2 receptor

    Toshio Nikaido;Akira Shimizu;Norio Ishida;Hisataka Sabe

  • Lymph Node Fibroblastic Reticular Cells Construct the Stromal Reticulum via Contact with Lymphocytes

    Tomoya Katakai;Takahiro Hara;Manabu Sugai;Hiroyuki Gonda

  • Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice

    Masao Murakami;Takeshi Tsubata;Masaya Okamoto;Akira Shimizu

  • Transcription-coupled events associating with immunoglobulin switch region chromatin.

    Yukiko Nambu;Manabu Sugai;Hiroyuki Gonda;Chung-Gi Lee

  • Organization of the constant-region gene family of the mouse immunoglobulin heavy chain

    Akira Shimizu;Naoki Takahashi;Yoshio Yaoita;Tasuku Honjo

  • Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis.

    Tobias Sjöblom;Akira Shimizu;Kevin P. O’Brien;Kristian Pietras

  • Organizer-Like Reticular Stromal Cell Layer Common to Adult Secondary Lymphoid Organs

    Tomoya Katakai;Hidenori Suto;Manabu Sugai;Hiroyuki Gonda

  • A transgenic model of autoimmune hemolytic anemia.

    M. Okamoto;M. Murakami;A. Shimizu;S. Ozaki

  • The Balance Between Pax5 and Id2 Activities Is the Key to AID Gene Expression

    Hiroyuki Gonda;Manabu Sugai;Yukiko Nambu;Tomoya Katakai

  • Circular DNA is excised by immunoglobulin class switch recombination.

    Takuji Iwasato;Akira Shimizu;Tasuku Honjo;Hideo Yamagishi

  • A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells

    Tomoya Katakai;Takahiro Hara;Jong-Hwan Lee;Hiroyuki Gonda

  • Pharmacokinetics, safety, and endocrine and appetite effects of ghrelin administration in young healthy subjects

    Takashi Akamizu;Kazuhiko Takaya;Taiga Irako;Hiroshi Hosoda

  • Immunoglobulin class switching.

    Akira Shimizu;Tasuku Honjo

  • Roles of p-ERM and Rho–ROCK signaling in lymphocyte polarity and uropod formation

    Jong-Hwan Lee;Tomoya Katakai;Takahiro Hara;Hiroyuki Gonda

  • Origin of human T-lymphotrophic virus I-positive T cell lines in adult T cell leukemia. Analysis of T cell receptor gene rearrangement.

    M Maeda;A Shimizu;K Ikuta;H Okamoto

  • The IL-7 receptor controls the accessibility of the TCRγ locus by Stat5 and histone acetylation

    Sang Kyu Ye;Yasutoshi Agata;Hai Chon Lee;Hisanori Kurooka

  • Mitochondrial function provides instructive signals for activation-induced B-cell fates.

    Kyoung Jin Jang;Hiroto Mano;Koji Aoki;Tatsunari Hayashi

  • Essential role of Id2 in negative regulation of IgE class switching

    Manabu Sugai;Hiroyuki Gonda;Takashi Kusunoki;Tomoya Katakai

Frequent Co-Authors

Tasuku Honjo
Tasuku Honjo Kyoto University
David H. Sachs
David H. Sachs Columbia University
Yoshifumi Yokota
Yoshifumi Yokota University of Fukui
Yuichi Yamamura
Yuichi Yamamura Osaka University
Robert B. Colvin
Robert B. Colvin Harvard University
Motomi Osato
Motomi Osato National University of Singapore
Satoshi Morita
Satoshi Morita Kyoto University
Masakazu Toi
Masakazu Toi Kyoto University
Hisataka Sabe
Hisataka Sabe Hokkaido University
K. Hicks
K. Hicks Ohio University

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