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Biology and Biochemistry

D-Index
52
Citations
12609
World Ranking
16532
National Ranking
6844

Overview

Paul Yaswen is affiliated with the Lawrence Berkeley National Laboratory in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology and cancer-related studies. Their work intersects important scientific topics including metabolism, diabetes, cancer, and the molecular mechanisms underlying these conditions.

Yaswen has contributed to various scientific publications with a focus on cancer research and associated molecular pathways. Notable recent papers include:

  • Overexpression of CD36 in mammary fibroblasts suppresses colony growth in breast cancer cell lines (2020, Biochemical and Biophysical Research Communications)
  • Protein Ligands in the Secretome of CD36+ Fibroblasts Induce Growth Suppression in a Subset of Breast Cancer Cell Lines (2021, Cancers)
  • Age-Associated Gene Expression in Normal Breast Tissue Mirrors Qualitative Age-at-Incidence Patterns for Breast Cancer (2020, UNC Libraries)

The scientist's research addresses several intricate topics, including Kruppel-like factors, fibroblast growth factor research, and TGF-β signaling pathways in diseases. Another emerging area in their portfolio is the application of artificial intelligence in cancer detection, combining computational methods with molecular biology.

Frequent colleagues in their research network include Kosar Jabbari, Garrett Winkelmaier, Cody Andersen, Qingsu Cheng, and Bahram Parvin, with multiple collaborations reflecting ongoing interdisciplinary scientific efforts.

Paul Yaswen has published in notable scientific venues such as Cancers, Biochemical and Biophysical Research Communications, and UNC Libraries. The diversity of publication platforms illustrates the breadth of their research scope, encompassing both bench science and computational approaches.

Their main fields of study cover:

  • Biochemistry, Genetics and Molecular Biology

The subfields where Yaswen is active include:

  • Molecular Biology
  • Cancer Research
  • Artificial Intelligence

The main topics addressed in Yaswen's research are:

  • Metabolism, Diabetes, and Cancer
  • Kruppel-like factors research
  • Fibroblast Growth Factor Research
  • Cancer, Lipids, and Metabolism
  • TGF-β signaling in diseases
  • AI in cancer detection

Best Publications

  • Reversal of human cellular senescence: roles of the p53 and p16 pathways

    Christian M. Beauséjour;Ana Krtolica;Francesco Galimi;Francesco Galimi;Masashi Narita

  • A versatile viral system for expression and depletion of proteins in mammalian cells.

    Eric Campeau;Victoria E. Ruhl;Francis Rodier;Francis Rodier;Corey Lewis Smith

  • Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells.

    Devon A. Lawson;Nirav R. Bhakta;Kai Kessenbrock;Kai Kessenbrock;Karin D. Prummel

  • ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium

    Kim Vy Nguyen-Ngoc;Kevin J. Cheung;Audrey Brenot;Eliah R. Shamir

  • In situ analyses of genome instability in breast cancer

    Koei Chin;Carlos Ortiz de Solorzano;David Knowles;Arthur Jones

  • MYC Pathway Activation in Triple-Negative Breast Cancer Is Synthetic Lethal With CDK Inhibition

    Dai Horiuchi;Leonard Kusdra;Noelle E. Huskey;Sanjay Chandriani;Sanjay Chandriani

  • Positional cloning of ZNF217 and NABC1: Genes amplified at 20q13.2 and overexpressed in breast carcinoma

    Colin Collins;Johanna M. Rommens;David Kowbel;Tony Godfrey

  • Designing a broad-spectrum integrative approach for cancer prevention and treatment

    Keith I. Block;Charlotte Gyllenhaal;Leroy Lowe;Amedeo Amedei

  • TANK2, a New TRF1-associated Poly(ADP-ribose) Polymerase, Causes Rapid Induction of Cell Death upon Overexpression

    Patrick G. Kaminker;Sahn Ho Kim;Rebecca D. Taylor;Yeganeh Zebarjadian

  • ELF magnetic fields, breast cancer, and melatonin: 60 Hz fields block melatonin's oncostatic action on ER+ breast cancer cell proliferation

    R.P. Liburdy;T.R. Sloma;R. Sokolic;P. Yaswen

  • Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells.

    C Sandhu;J Garbe;N Bhattacharya;J Daksis

  • Activation of NF-κB/Rel occurs early during neoplastic transformation of mammary cells

    Dong W. Kim;Mika A. Sovak;Gregory Zanieski;Genevieve Nonet

  • Keratins as markers that distinguish normal and tumor-derived mammary epithelial cells

    Douglas K. Trask;Vimla Band;Deborah A. Zajchowski;Paul Yaswen

  • Experimental evidence for 60 Hz magnetic fields operating through the signal transduction cascade: Effects on calcium influx and c-MYC mRNA induction

    R.P. Liburdy;D.E. Callahan;J. Harland;E. Dunham

  • Oncogene-Induced Senescence Pathways Weave an Intricate Tapestry

    Paul Yaswen;Judith Campisi;Judith Campisi

  • The ZNF217 Gene Amplified in Breast Cancers Promotes Immortalization of Human Mammary Epithelial Cells

    Genevieve H. Nonet;Martha R. Stampfer;Koei Chin;Joe W. Gray

  • Expression of c-Ki-ras, c-Ha-ras, and c-myc in specific cell types during hepatocarcinogenesis.

    P Yaswen;M Goyette;P R Shank;N Fausto

  • Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells.

    Martha R. Stampfer;James Garbe;Gerri Levine;Serge Lichtsteiner

  • Effects of Sequence of Thioated Oligonucleotides on Cultured Human Mammary Epithelial Cells

    Paul Yaswen;Martha R. Stampfer;Krishna Ghosh;Jack S. Cohen

  • Cancer and aging: the importance of telomeres in genome maintenance.

    Francis Rodier;Sahn Ho Kim;Tarlochan Nijjar;Paul Yaswen

Frequent Co-Authors

Martha R. Stampfer
Martha R. Stampfer Lawrence Berkeley National Laboratory
Judith Campisi
Judith Campisi Buck Institute for Research on Aging
Joe W. Gray
Joe W. Gray Oregon Health & Science University
Zena Werb
Zena Werb University of California, San Francisco
Andrei Goga
Andrei Goga University of California, San Francisco
Mina J. Bissell
Mina J. Bissell Lawrence Berkeley National Laboratory
Nelson Fausto
Nelson Fausto University of Washington
Christina Yau
Christina Yau University of California, San Francisco
Colin Collins
Colin Collins University of British Columbia
Michael T. McManus
Michael T. McManus University of California, San Francisco

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